Featured Research

from universities, journals, and other organizations

New, Less Invasive Repair Of Major Artery Defect

Date:
July 13, 1999
Source:
University Of North Carolina School Of Medicine
Summary:
Physicians at the University of North Carolina at Chapel Hill are testing a new, less invasive method for repairing abdominal aortic aneurysms, potentially dangerous defects of the body's major artery found often in the elderly.

CHAPEL HILL - Physicians at the University of North Carolina at Chapel Hill are testing a new, less invasive method for repairing abdominal aortic aneurysms, potentially dangerous defects of the body's major artery found often in the elderly.

If clinical trials continue to show promise, the newer repair method could offer an alternative to the standard major operation that requires opening the entire abdomen, a hospital stay of seven to 10 days and six weeks for recovery. In early experience with the newer procedure, patients were able to leave the hospital in about two days and were back to normal activity within two weeks, according to Dr. William Marston, assistant professor of surgery at UNC-CH School of Medicine.

"The standard surgery for abdominal aortic aneurysm is very good and has been used extensively over the last 25 years," Marston says. "On the downside, mortality rates are between two and four percent and may prove too risky for people with cardiac, pulmonary, or other disorders."

In the less invasive endovascular repair, an incision of about two inches is made in the groin, through which a thin artery graft supported by a metal framework, or stent, is threaded via a guide wire into the defective segment of aorta. The stented graft, when heated by normal body temperature, quickly expands to the width of a normal aorta. Positioned inside the ballooned-out aneurysm, the graft is anchored to healthy aorta above and below it.

"You must have normal aorta above and below the aneurysm to anchor the device so that the blood flows through the stented graft inside it. This prevents blood flow pressure from rupturing the thinned-out aneurysm," Marston explains.

According to the UNC vascular surgeon, he and Dr. Matthew Mauro, an interventional radiologist and professor of radiology, are principal investigators at one of selected sites conducting clinical trials evaluating the Vanguard prosthesis. This is one of several stented grafts undergoing studies in the U.S.

"To effectively treat the aneurysm, we have to know if these devices will exclude the aneurysm over the long run. So far, in almost two years, our UNC group has had success in aneurysm exclusion in 90% of patients, Marston says, adding that clinical reports from Europe of similar repairs have noted acceptable success for longer periods of time.

At UNC, a multi-specialty center has been developed to offer endovascular techniques combining the skills of surgical and interventional radiology experts. Marston points out that the unique skills these specialists bring to the procedure "have combined to produce optimal results."

"This is clearly a procedure that requires extensive training to develop the skills necessary to do it safely and to do it with the best outcomes for patients," he states. "At UNC, we've performed over 30 cases with successful results, an accomplishment matched by only a few centers nationally."

The procedure is performed in an operating suite especially modified to ensure that a standard operation can be performed if necessary, which has occurred in fewer that 5% of cases, notes Marston .

The UNC team will soon open another clinical trial for people with abdominal aortic aneurysms that require repair. "We will again have prostheses available for any patient who has an aneurysm that is anatomically correctable with the device," Marston says.

"It's definitely a technology that needs longer-term follow-up. We're following our patients very carefully and recommend they come back to us every six months for examination. But we believe that for some patients it clearly has the potential to reduce the risks of aneurysm repair."


Story Source:

The above story is based on materials provided by University Of North Carolina School Of Medicine. Note: Materials may be edited for content and length.


Cite This Page:

University Of North Carolina School Of Medicine. "New, Less Invasive Repair Of Major Artery Defect." ScienceDaily. ScienceDaily, 13 July 1999. <www.sciencedaily.com/releases/1999/07/990713074048.htm>.
University Of North Carolina School Of Medicine. (1999, July 13). New, Less Invasive Repair Of Major Artery Defect. ScienceDaily. Retrieved October 20, 2014 from www.sciencedaily.com/releases/1999/07/990713074048.htm
University Of North Carolina School Of Medicine. "New, Less Invasive Repair Of Major Artery Defect." ScienceDaily. www.sciencedaily.com/releases/1999/07/990713074048.htm (accessed October 20, 2014).

Share This



More Health & Medicine News

Monday, October 20, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Microneedle Patch Promises Painless Pricks

Microneedle Patch Promises Painless Pricks

Reuters - Innovations Video Online (Oct. 18, 2014) Researchers at The National University of Singapore have invented a new microneedle patch that could offer a faster and less painful delivery of drugs such as insulin and painkillers. Video provided by Reuters
Powered by NewsLook.com
Raw: Nurse Nina Pham Arrives in Maryland

Raw: Nurse Nina Pham Arrives in Maryland

AP (Oct. 17, 2014) The first nurse to be diagnosed with Ebola at a Dallas hospital walked down the stairs of an executive jet into an ambulance at an airport in Frederick, Maryland, on Thursday. Pham will be treated at the National Institutes of Health. (Oct. 16) Video provided by AP
Powered by NewsLook.com
Raw: Cruise Ship Returns to US Over Ebola Fears

Raw: Cruise Ship Returns to US Over Ebola Fears

AP (Oct. 17, 2014) A Caribbean cruise ship carrying a Dallas health care worker who is being monitored for signs of the Ebola virus is heading back to Texas, US, after being refused permission to dock in Cozumel, Mexico. (Oct. 17) Video provided by AP
Powered by NewsLook.com
Spanish Govt: Four Suspected Ebola Cases in Spain Test Negative

Spanish Govt: Four Suspected Ebola Cases in Spain Test Negative

AFP (Oct. 17, 2014) All four suspected Ebola cases admitted to hospitals in Spain on Thursday have tested negative for the deadly virus in a first round of tests, the government said Friday. Duration: 00:55 Video provided by AFP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins