Featured Research

from universities, journals, and other organizations

Gene Plays An Early Role In Development Of Colon Cancer

Date:
February 25, 2000
Source:
Cedars-Sinai Medical Center
Summary:
A team of Cedars-Sinai Research Institute investigators reports in the Feb. 26 issue of The Lancet the discovery that PTTG1, a novel transforming gene that incites the development and growth of pituitary tumors, is also expressed in colorectal tumors, pre-cancerous colorectal polyps, and abundantly in invasive colorectal cancer. The pituitary tumor transforming gene may prove to be a powerful tool for identifying the colon polyps most at risk for becoming malignant, and for distinguishing aggressive colorectal cancer. The discovery may lead to new therapeutic strategies as well. A commentary on the article also appears in the Lancet's Feb. 26 issue.

LOS ANGELES (EMBARGOED UNTIL FEB. 24, 2000 @ 6:30 p.m. EST) -- A gene that incites the development and growth of pituitary tumors is also expressed in colorectal tumors, pre-cancerous colorectal polyps, and, most abundantly, in invasive colorectal cancer, researchers at Cedars-Sinai Medical Center's Burns & Allen Research Institute report in this week’s The Lancet. "The novel transforming gene known as Pituitary Tumor Transforming Gene (PTTG1) may prove to be a powerful tool for identifying colon polyps most at risk for becoming malignant and for distinguishing aggressive colorectal cancer, the third leading cause of cancer death in the U.S." said Anthony P. Heaney, M.D., lead author of the Lancet paper.


Story Source:

The above story is based on materials provided by Cedars-Sinai Medical Center. Note: Materials may be edited for content and length.


Cite This Page:

Cedars-Sinai Medical Center. "Gene Plays An Early Role In Development Of Colon Cancer." ScienceDaily. ScienceDaily, 25 February 2000. <www.sciencedaily.com/releases/2000/02/000223020222.htm>.
Cedars-Sinai Medical Center. (2000, February 25). Gene Plays An Early Role In Development Of Colon Cancer. ScienceDaily. Retrieved April 20, 2014 from www.sciencedaily.com/releases/2000/02/000223020222.htm
Cedars-Sinai Medical Center. "Gene Plays An Early Role In Development Of Colon Cancer." ScienceDaily. www.sciencedaily.com/releases/2000/02/000223020222.htm (accessed April 20, 2014).

Share This



More Health & Medicine News

Sunday, April 20, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Nine-Month-Old Baby Can't Open His Mouth

Nine-Month-Old Baby Can't Open His Mouth

Newsy (Apr. 19, 2014) Nine-month-old Wyatt Scott was born with a rare disorder called congenital trismus, which prevents him from opening his mouth. Video provided by Newsy
Powered by NewsLook.com
'Holy Grail' Of Weight Loss? New Find Could Be It

'Holy Grail' Of Weight Loss? New Find Could Be It

Newsy (Apr. 18, 2014) In a potential breakthrough for future obesity treatments, scientists have used MRI scans to pinpoint brown fat in a living adult for the first time. Video provided by Newsy
Powered by NewsLook.com
Little Progress Made In Fighting Food Poisoning, CDC Says

Little Progress Made In Fighting Food Poisoning, CDC Says

Newsy (Apr. 18, 2014) A new report shows rates of two foodborne infections increased in the U.S. in recent years, while salmonella actually dropped 9 percent. Video provided by Newsy
Powered by NewsLook.com
Scientists Create Stem Cells From Adult Skin Cells

Scientists Create Stem Cells From Adult Skin Cells

Newsy (Apr. 17, 2014) The breakthrough could mean a cure for some serious diseases and even the possibility of human cloning, but it's all still a way off. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins