Featured Research

from universities, journals, and other organizations

In-Home Pesticide Exposure Increases Parkinson’s Risk

Date:
May 9, 2000
Source:
American Academy Of Neurology
Summary:
Pesticide use and exposure in the home and garden increase the risk of developing Parkinson’s disease, according to a study of almost 500 people newly diagnosed with the disease. Researchers announced their findings at a presentation at the American Academy of Neurology’s 52nd annual meeting in San Diego, CA, April 29 – May 6, 2000.

SAN DIEGO, CA – Pesticide use and exposure in the home and garden increase the risk of developing Parkinson’s disease, according to a study of almost 500 people newly diagnosed with the disease. Researchers announced their findings at a presentation at the American Academy of Neurology’s 52nd annual meeting in San Diego, CA, April 29 – May 6, 2000.

Related Articles


"This study is the largest yet of newly diagnosed individuals with Parkinson's disease and it is the first study to show a significant association between home pesticide use and the risk of developing

Parkinson's disease," said study lead author Lorene Nelson, PhD, a neuroepidemiologist at Stanford University School of Medicine. The preliminary results from this study mirror what is already known about the increased risk of Parkinson's disease associated with occupational exposure to pesticides.

The researchers questioned 496 people who had been diagnosed with Parkinson's disease about past use of pesticides. Each patient was asked if they had used or been exposed to insecticides in the home or garden, herbicides or weed killers in the garden, or fungicides to control mold or mildew in the home or garden. Researchers asked detailed questions about past pesticide use including first exposures and frequency of pesticide contact.

The Parkinson’s patients’ lifetime histories were then compared to 541 people without the disease. Researchers found that people who had been exposed to pesticides were approximately two times more likely to develop Parkinson's disease than people not exposed to pesticides.

In-home exposure to insecticides carried the highest risk of developing the disease. Parkinson’s patients were more than twice as likely to have been exposed to insecticides in the home than those without the disease. Past exposure to herbicides was also associated with the disease, whereas exposure to insecticides in the garden and fungicides were not found to be risk factors.

Damage to nerve cells in a part of the brain called the substantia nigra leads to the movement difficulties characteristic of Parkinson's disease. Therefore, people exposed to chemicals that have a particular affinity for this region of the brain may be at particular risk for developing the disease.

"Certain chemicals that an individual is exposed to in the environment may cause selective death of brain cells or neurons," stated Nelson. "If we could understand why these neurons are being killed in certain circumstances, we can then try and prevent it."

But Nelson cautioned that more studies are needed before any conclusive statements can be made about the causes of Parkinson's disease, including any genetic influence on a person's probability of developing the disease.

Nelson also stressed that the results of the study must be interpreted with caution. "No specific guidelines regarding avoidance of pesticides can be given at this time but, in general, this is an area of public health importance that needs to be pursued," said Nelson.

Parkinson’s disease is a slowly progressive, neurodegenerative disease that affects more than 500,000 people in the United States. Parkinson’s causes the loss of dopamine, a chemical in the brain, which results in muscle stiffness and rigidity, slowness in movement and tremor of the arms and legs.

The National Institutes of Health provided funding for the study.

The American Academy of Neurology, an association of more than 16,500 neurologists and neuroscience professionals, is dedicated to improving patient care through education and research. For more information about the American Academy of Neurology, visit its Web site at http://www.aan.com. For online neurological health and wellness information, visit NeuroVista at http://www.aan.com/neurovista.


Story Source:

The above story is based on materials provided by American Academy Of Neurology. Note: Materials may be edited for content and length.


Cite This Page:

American Academy Of Neurology. "In-Home Pesticide Exposure Increases Parkinson’s Risk." ScienceDaily. ScienceDaily, 9 May 2000. <www.sciencedaily.com/releases/2000/05/000508082430.htm>.
American Academy Of Neurology. (2000, May 9). In-Home Pesticide Exposure Increases Parkinson’s Risk. ScienceDaily. Retrieved October 25, 2014 from www.sciencedaily.com/releases/2000/05/000508082430.htm
American Academy Of Neurology. "In-Home Pesticide Exposure Increases Parkinson’s Risk." ScienceDaily. www.sciencedaily.com/releases/2000/05/000508082430.htm (accessed October 25, 2014).

Share This



More Health & Medicine News

Saturday, October 25, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Texas Nurse Nina Pham Cured of Ebola

Texas Nurse Nina Pham Cured of Ebola

AFP (Oct. 25, 2014) — An American nurse who contracted Ebola while caring for a Liberian patient in Texas has been declared free of the virus and will leave the hospital. Duration: 01:01 Video provided by AFP
Powered by NewsLook.com
IKEA Desk Converts From Standing to Sitting With One Button

IKEA Desk Converts From Standing to Sitting With One Button

Buzz60 (Oct. 24, 2014) — IKEA is out with a new convertible desk that can convert from a sitting desk to a standing one with just the push of a button. Jen Markham explains. Video provided by Buzz60
Powered by NewsLook.com
Ebola Protective Suits Being Made in China

Ebola Protective Suits Being Made in China

AFP (Oct. 24, 2014) — A factory in China is busy making Ebola protective suits for healthcare workers and others fighting the spread of the virus. Duration: 00:38 Video provided by AFP
Powered by NewsLook.com
WHO: Millions of Ebola Vaccine Doses by 2015

WHO: Millions of Ebola Vaccine Doses by 2015

AP (Oct. 24, 2014) — The World Health Organization said on Friday that millions of doses of two experimental Ebola vaccines could be ready for use in 2015 and five more experimental vaccines would start being tested in March. (Oct. 24) Video provided by AP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:

Strange & Offbeat Stories

 

Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins