Featured Research

from universities, journals, and other organizations

National Jewish Expert Says Bacteria By-Product Found In Household Dust May Protect Infants From Asthma Later In Life

Date:
May 12, 2000
Source:
National Jewish Medical And Research Center
Summary:
Cleanliness may be next to godliness, but National Jewish Medical and Research Center researchers say that a little dust and dirt in the home may help prevent asthma later in life.

DENVER -- Cleanliness may be next to godliness, but National Jewish Medical and Research Center researchers say that a little dust and dirt in the home may help prevent asthma later in life. Environmental endotoxin may have an allergy-protective effect in some infants whose homes have high levels of the bacteria by-product. “Endotoxin seems to drive the immune system to produce cytokines that inhibit certain processes in the body that may lead to asthma,” said Andy Liu, M.D., a National Jewish childhood asthma specialist and principal author of the article today’s issue of The Lancet.

Related Articles


Children not sensitized to common inhaled and food allergens had significantly higher endotoxin levels in their homes—more than twice as high—as children who were sensitive to the same allergens. Allergens can trigger an asthma attack for many of 17 million children and adults in the United States with the lung disease.

“Exposure to endotoxin may play a role in the prevention of allergen sensitization during infancy,” he said. However, if a child or adult already has asthma or allergies, the presence of endotoxin in the home can exacerbate the disease.

National Jewish researchers studied the homes of 61 infants, 9-24 months old, with at least three documented episodes of wheezing, which can be an early indicator of asthma. The infants were tested for sensitivity to dust mite, cat, dog, cockroach, mouse, milk, egg and soy.

Of the 61 asthma-prone infants, 51 tested negative to these inhaled and food allergens. In the homes of children with negative allergen skin tests, the concentration of endotoxin was the highest.

“Children who are allergen-sensitive have less environmental endotoxin in their homes,” Dr. Liu said. “The amount of environmental endotoxin seems to correlate with immune system development.”

Endotoxin levels were determined by checking house dust collected from the living room, kitchen and bedroom floors, a couch and the child’s bed. Endotoxin is part of the cell wall of common bacteria. When bacteria die, the cell wall collapses and endotoxin is released into the environment, finding its way into the air and dust. Bacteria that produce endotoxin are found in soil, and the feces of human and animals, including household pets.

Because asthma rates are very low in many agriculture-based countries and farming communities—compared to metropolitan areas—researchers believe that early exposure to environmental endotoxin may provide protection against developing asthma later in life.

“These findings suggest that one common thread in these communities, where allergies and asthma are uncommon, may be early childhood exposure to environmental endotoxin. This may be an important clue in the development of effective and safe asthma prevention,” Dr. Liu said. For more information about asthma and endotoxin, call LUNG LINE, (800) 222-LUNG, or e-mail, lungline@njc.org.


Story Source:

The above story is based on materials provided by National Jewish Medical And Research Center. Note: Materials may be edited for content and length.


Cite This Page:

National Jewish Medical And Research Center. "National Jewish Expert Says Bacteria By-Product Found In Household Dust May Protect Infants From Asthma Later In Life." ScienceDaily. ScienceDaily, 12 May 2000. <www.sciencedaily.com/releases/2000/05/000509111626.htm>.
National Jewish Medical And Research Center. (2000, May 12). National Jewish Expert Says Bacteria By-Product Found In Household Dust May Protect Infants From Asthma Later In Life. ScienceDaily. Retrieved October 31, 2014 from www.sciencedaily.com/releases/2000/05/000509111626.htm
National Jewish Medical And Research Center. "National Jewish Expert Says Bacteria By-Product Found In Household Dust May Protect Infants From Asthma Later In Life." ScienceDaily. www.sciencedaily.com/releases/2000/05/000509111626.htm (accessed October 31, 2014).

Share This



More Health & Medicine News

Friday, October 31, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Melafind: Spotting Melanoma Without a Biopsy

Melafind: Spotting Melanoma Without a Biopsy

Ivanhoe (Oct. 31, 2014) The MelaFind device is a pain-free way to check suspicious moles for melanoma, without the need for a biopsy. Video provided by Ivanhoe
Powered by NewsLook.com
Battling Multiple Myeloma

Battling Multiple Myeloma

Ivanhoe (Oct. 31, 2014) The answer isn’t always found in new drugs – repurposing an ‘old’ drug that could mean better multiple myeloma treatment, and hope. Video provided by Ivanhoe
Powered by NewsLook.com
Chronic Inflammation and Prostate Cancer

Chronic Inflammation and Prostate Cancer

Ivanhoe (Oct. 31, 2014) New information that is linking chronic inflammation in the prostate and prostate cancer, which may help doctors and patients prevent cancer in the future. Video provided by Ivanhoe
Powered by NewsLook.com
Sickle Cell: Stopping Kids’ Silent Strokes

Sickle Cell: Stopping Kids’ Silent Strokes

Ivanhoe (Oct. 31, 2014) Blood transfusions are proving crucial to young sickle cell patients by helping prevent strokes, even when there is no outward sign of brain injury. Video provided by Ivanhoe
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins