An article in today’s Federation of American Societies for Experimental Biology (FASEB) Journal (Chen, S; Wilkemeyer, M; Sulik, K; and Charness, M. Octanol antagonism of ethanol teratogenesis, FASEB J. 10.1096/fj00-08620fje and Volume 15, Number 9, July 2001) reports that the long-chain alcohol 1-octanol successfully blocks a mechanism leading to fetal alcohol syndrome (FAS). Viewed as paradoxical because it is the short-chain alcohol ethanol (beverage alcohol) that causes FAS, today’s finding nevertheless suggests a strategy for developing pharmaceutical interventions to prevent alcohol-related birth defects.
The above story is based on materials provided by NIH/National Institute On Alcohol Abuse And Alcoholism. Note: Materials may be edited for content and length.
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