Featured Research

from universities, journals, and other organizations

ACE Inhibitor Reduces The Risk Of Kidney Failure In Hypertensives

Date:
June 14, 2001
Source:
NIH/National Institute Of Diabetes And Digestive And Kidney Diseases
Summary:
People with kidney disease from high blood pressure have a better chance of reducing the risk of kidney failure if they take an angiotensin-converting enzyme (ACE) inhibitor, according to a National Institutes of Health study in the Journal of the American Medical Association on June 6.

People with kidney disease from high blood pressure have a better chance of reducing the risk of kidney failure if they take an angiotensin-converting enzyme (ACE) inhibitor, according to a National Institutes of Health study in the Journal of the American Medical Association on June 6.

Related Articles


The African American Study of Kidney Disease and Hypertension (AASK) found that the ACE inhibitor ramipril (Altaceฎ) slowed kidney disease by 36 percent and slashed the risk of kidney failure and death by 48 percent in patients who had at least a gram of protein in the urine. The drug was compared to the dihydropyridine calcium channel blocker amlodipine (CCB, Norvascฎ). Results were not related to blood pressure control, which was comparable between study groups.

ACE inhibitors have been the preferred treatment for kidney disease of diabetes since 1994, and now AASK doctors are recommending it for kidney disease of hypertension, especially for people who also have protein in the urine. While CCBs help many patients, particularly African Americans, control blood pressure and reduce the risk of stroke and heart disease, patients may need an ACE inhibitor to protect the kidneys.

AASK stopped using the CCB as a main-line treatment in September 2000 on the advice of a data and safety monitoring board. AASK investigators will continue to compare the ACE inhibitor and the beta blocker metoprolol (Toprol XLฎ) and two blood pressure goals until the fall of 2001, when the study will end.

African Americans make up 13.9 percent of the U.S. population but 29.8 percent of people treated for kidney failure. Hardest hit are blacks ages 25 to 44, who are 20 times more vulnerable to hypertensive kidney failure. Better management of high blood pressure has led to fewer strokes and heart disease, but kidney failure is increasing. In 1998, nearly 398,000 people were treated for kidney failure in the United States, costing an average $43,000 per person for a total of $16.7 billion.


Story Source:

The above story is based on materials provided by NIH/National Institute Of Diabetes And Digestive And Kidney Diseases. Note: Materials may be edited for content and length.


Cite This Page:

NIH/National Institute Of Diabetes And Digestive And Kidney Diseases. "ACE Inhibitor Reduces The Risk Of Kidney Failure In Hypertensives." ScienceDaily. ScienceDaily, 14 June 2001. <www.sciencedaily.com/releases/2001/06/010611071006.htm>.
NIH/National Institute Of Diabetes And Digestive And Kidney Diseases. (2001, June 14). ACE Inhibitor Reduces The Risk Of Kidney Failure In Hypertensives. ScienceDaily. Retrieved December 20, 2014 from www.sciencedaily.com/releases/2001/06/010611071006.htm
NIH/National Institute Of Diabetes And Digestive And Kidney Diseases. "ACE Inhibitor Reduces The Risk Of Kidney Failure In Hypertensives." ScienceDaily. www.sciencedaily.com/releases/2001/06/010611071006.htm (accessed December 20, 2014).

Share This


More From ScienceDaily



More Health & Medicine News

Saturday, December 20, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

The Best Tips to Curb Holiday Carbs

The Best Tips to Curb Holiday Carbs

Buzz60 (Dec. 19, 2014) — It's hard to resist those delicious but fattening carbs we all crave during the winter months, but there are some ways to stay satisfied without consuming the extra calories. Vanessa Freeman (@VanessaFreeTV) has the details. Video provided by Buzz60
Powered by NewsLook.com
Sierra Leone Bikers Spread the Message to Fight Ebola

Sierra Leone Bikers Spread the Message to Fight Ebola

AFP (Dec. 19, 2014) — More than 100 motorcyclists hit the road to spread awareness messages about Ebola. Nearly 7,000 people have now died from the virus, almost all of them in west Africa, according to the World Health Organization. Video provided by AFP
Powered by NewsLook.com
Researchers Test Colombian Village With High Alzheimer's Rates

Researchers Test Colombian Village With High Alzheimer's Rates

AFP (Dec. 19, 2014) — In Yarumal, a village in N. Colombia, Alzheimer's has ravaged a disproportionately large number of families. A genetic "curse" that may pave the way for research on how to treat the disease that claims a new victim every four seconds. Duration: 02:42 Video provided by AFP
Powered by NewsLook.com
The Best Protein-Filled Foods to Energize You for the New Year

The Best Protein-Filled Foods to Energize You for the New Year

Buzz60 (Dec. 19, 2014) — The new year is coming and nothing will energize you more for 2015 than protein-filled foods. Fitness and nutrition expert John Basedow (@JohnBasedow) gives his favorite high protein foods that will help you build muscle, lose fat and have endless energy. Video provided by Buzz60
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:

Strange & Offbeat Stories

 

Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins