Featured Research

from universities, journals, and other organizations

The World's Most Powerful NMR Spectrometer

Date:
June 26, 2001
Source:
Scripps Research Institute
Summary:
The most powerful, high-resolution nuclear magnet resonance (NMR) spectrometer ever constructed was delivered today to The Scripps Research Institute (TSRI). According to Peter Wright, Ph.D., Chairman, Department of Molecular Biology, the new NMR, referred to by the frequency at which it operates, 900 MHz, will become the centerpiece of one of the world's most prominent collections of NMR instruments.

The most powerful, high-resolution nuclear magnet resonance (NMR) spectrometer ever constructed was delivered today to The Scripps Research Institute (TSRI). According to Peter Wright, Ph.D., Chairman, Department of Molecular Biology, the new NMR, referred to by the frequency at which it operates, 900 MHz, will become the centerpiece of one of the world's most prominent collections of NMR instruments.

Wright commented, "It's fantastic. The capabilities of this instrument take us to a new level."

The instrument is the first of its kind and has been several years in the making by its German manufacturer, Bruker Instruments, Inc.

TSRI is a leader in high-powered NMR instrumentation, with 10 instruments at or above 500 MHz. Wright continued, "It's a very big deal to have the first major instrument of this type in this city. It reinforces our position at the leading edge of molecular and structural biology."

NMR spectroscopy is a diagnostic tool for chemistry and biology; additionally, it forms the basis for the technique of magnetic resonance imaging (MRI) in medicine. In a research context, NMR provides atomic coordinates of a wide range of biologically important molecules in solution. This information enables scientists to determine the structure-function relationships of molecules that lie at the heart of understanding fundamental biological processes.

Determining the three-dimensional structures of proteins and nucleic acids provides important insights into the basic questions about how living organisms function and change, and how particular alterations can lead to human disease. Structural biology is seen by scientists as particularly important in today's research environment: while the genomes of humans and several other organisms have been solved, the structures of most of the proteins which the tens of thousands of genes encode remain a mystery.

In an NMR experiment, a sample in a long tube is inserted into the magnet, which consists of several superconducting coils surrounded by an outer dewar containing liquid helium. Atomic nuclei of molecules inside the tube give detectable responses to a radio frequency signal emitted by the inner coil at varying "resonance" frequencies.

A typical experiment involves scanning a range of frequencies and recording the responses of the atoms in the sample. These responses are influenced by the shape of the molecule in which the atoms reside – by their proximity to other atoms in the molecule. An NMR spectrum is unique for a particular molecule, and the structure of a molecule can be determined from its spectrum.


Story Source:

The above story is based on materials provided by Scripps Research Institute. Note: Materials may be edited for content and length.


Cite This Page:

Scripps Research Institute. "The World's Most Powerful NMR Spectrometer." ScienceDaily. ScienceDaily, 26 June 2001. <www.sciencedaily.com/releases/2001/06/010611072959.htm>.
Scripps Research Institute. (2001, June 26). The World's Most Powerful NMR Spectrometer. ScienceDaily. Retrieved August 2, 2014 from www.sciencedaily.com/releases/2001/06/010611072959.htm
Scripps Research Institute. "The World's Most Powerful NMR Spectrometer." ScienceDaily. www.sciencedaily.com/releases/2001/06/010611072959.htm (accessed August 2, 2014).

Share This




More Health & Medicine News

Saturday, August 2, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Texas Quintuplets Head Home

Texas Quintuplets Head Home

Reuters - US Online Video (Aug. 1, 2014) After four months in the hospital, the first quintuplets to be born at Baylor University Medical Center head home. Linda So reports. Video provided by Reuters
Powered by NewsLook.com
Ebola Patient Coming to U.S. for Treatment

Ebola Patient Coming to U.S. for Treatment

Reuters - US Online Video (Aug. 1, 2014) A U.S. aid worker infected with Ebola while working in West Africa will be treated in a high security ward at Emory University in Atlanta. Linda So reports. Video provided by Reuters
Powered by NewsLook.com
Ebola Vaccine Might Be Coming, But Where's It Been?

Ebola Vaccine Might Be Coming, But Where's It Been?

Newsy (Aug. 1, 2014) Health officials are working to fast-track a vaccine — the West-African Ebola outbreak has killed more than 700. But why didn't we already have one? Video provided by Newsy
Powered by NewsLook.com
Study Links Certain Birth Control Pills To Breast Cancer

Study Links Certain Birth Control Pills To Breast Cancer

Newsy (Aug. 1, 2014) Previous studies have made the link between birth control and breast cancer, but the latest makes the link to high-estrogen oral contraceptives. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins