Featured Research

from universities, journals, and other organizations

The World's Most Powerful NMR Spectrometer

Date:
June 26, 2001
Source:
Scripps Research Institute
Summary:
The most powerful, high-resolution nuclear magnet resonance (NMR) spectrometer ever constructed was delivered today to The Scripps Research Institute (TSRI). According to Peter Wright, Ph.D., Chairman, Department of Molecular Biology, the new NMR, referred to by the frequency at which it operates, 900 MHz, will become the centerpiece of one of the world's most prominent collections of NMR instruments.

The most powerful, high-resolution nuclear magnet resonance (NMR) spectrometer ever constructed was delivered today to The Scripps Research Institute (TSRI). According to Peter Wright, Ph.D., Chairman, Department of Molecular Biology, the new NMR, referred to by the frequency at which it operates, 900 MHz, will become the centerpiece of one of the world's most prominent collections of NMR instruments.

Wright commented, "It's fantastic. The capabilities of this instrument take us to a new level."

The instrument is the first of its kind and has been several years in the making by its German manufacturer, Bruker Instruments, Inc.

TSRI is a leader in high-powered NMR instrumentation, with 10 instruments at or above 500 MHz. Wright continued, "It's a very big deal to have the first major instrument of this type in this city. It reinforces our position at the leading edge of molecular and structural biology."

NMR spectroscopy is a diagnostic tool for chemistry and biology; additionally, it forms the basis for the technique of magnetic resonance imaging (MRI) in medicine. In a research context, NMR provides atomic coordinates of a wide range of biologically important molecules in solution. This information enables scientists to determine the structure-function relationships of molecules that lie at the heart of understanding fundamental biological processes.

Determining the three-dimensional structures of proteins and nucleic acids provides important insights into the basic questions about how living organisms function and change, and how particular alterations can lead to human disease. Structural biology is seen by scientists as particularly important in today's research environment: while the genomes of humans and several other organisms have been solved, the structures of most of the proteins which the tens of thousands of genes encode remain a mystery.

In an NMR experiment, a sample in a long tube is inserted into the magnet, which consists of several superconducting coils surrounded by an outer dewar containing liquid helium. Atomic nuclei of molecules inside the tube give detectable responses to a radio frequency signal emitted by the inner coil at varying "resonance" frequencies.

A typical experiment involves scanning a range of frequencies and recording the responses of the atoms in the sample. These responses are influenced by the shape of the molecule in which the atoms reside – by their proximity to other atoms in the molecule. An NMR spectrum is unique for a particular molecule, and the structure of a molecule can be determined from its spectrum.


Story Source:

The above story is based on materials provided by Scripps Research Institute. Note: Materials may be edited for content and length.


Cite This Page:

Scripps Research Institute. "The World's Most Powerful NMR Spectrometer." ScienceDaily. ScienceDaily, 26 June 2001. <www.sciencedaily.com/releases/2001/06/010611072959.htm>.
Scripps Research Institute. (2001, June 26). The World's Most Powerful NMR Spectrometer. ScienceDaily. Retrieved August 20, 2014 from www.sciencedaily.com/releases/2001/06/010611072959.htm
Scripps Research Institute. "The World's Most Powerful NMR Spectrometer." ScienceDaily. www.sciencedaily.com/releases/2001/06/010611072959.htm (accessed August 20, 2014).

Share This




More Health & Medicine News

Wednesday, August 20, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Ebola-Hit Sierra Leone's Freetown a City on Edge

Ebola-Hit Sierra Leone's Freetown a City on Edge

AFP (Aug. 19, 2014) Residents of Sierra Leone's capital voice their fears as the Ebola virus sweeps through west Africa. Duration: 00:56 Video provided by AFP
Powered by NewsLook.com
101-Year-Old Working Man Has All The Advice You Need

101-Year-Old Working Man Has All The Advice You Need

Newsy (Aug. 19, 2014) Herman Goldman has worked at the same lighting store for almost 75 years. Find out his secrets to a happy, productive life. Video provided by Newsy
Powered by NewsLook.com
Researcher Testing on-Field Concussion Scanners

Researcher Testing on-Field Concussion Scanners

AP (Aug. 19, 2014) Four Texas high school football programs are trying out an experimental system designed to diagnose concussions on the field. The technology is in response to growing concern over head trauma in America's most watched sport. (Aug. 19) Video provided by AP
Powered by NewsLook.com
American Ebola Patient Apparently Improving, Outbreak Is Not

American Ebola Patient Apparently Improving, Outbreak Is Not

Newsy (Aug. 19, 2014) Nancy Writebol, an American missionary who contracted Ebola, is apparently getting better, according to her husband. The outbreak, however, is not. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins