Featured Research

from universities, journals, and other organizations

Biocapsule Can Provide Steady Insulin Supply; Potential Breakthrough For Diabetes Patients

Date:
October 31, 2001
Source:
National Science Foundation
Summary:
Pushing the frontiers of drug delivery technology, a biomedical engineer at the University of Illinois at Chicago has developed an implantable capsule that releases a steady supply of insulin to the bloodstream of people with diabetes.

Pushing the frontiers of drug delivery technology, a biomedical engineer at the University of Illinois at Chicago has developed an implantable capsule that releases a steady supply of insulin to the bloodstream of people with diabetes. The biocapsule, developed by Tejal Desai with support from the National Science Foundation (NSF), features two innovations designed to overcome previous obstacles. A biological process allows the capsule to continuously produce insulin, rather than using up a limited supply. The capsule is made of a material designed to overcome the problem of implant rejection.

"The capsule essentially acts as a bioreactor; it contains insulin-secreting cells that borrow nutrients from the body to keep producing insulin indefinitely," Desai said. "As long as the body produces glucose, the cells will respond with insulin."

Desai has also broken new ground by developing a successfully implantable micro-scale device. Tiny devices made with microchip technology have been researched extensively for implantable medical applications, but biocompatibility has been a continuing problem.

To prevent the capsule from being attacked and destroyed by the immune system, Desai developed a silicon membrane covered with tiny uniform pores, each seven nanometers across. The membrane acts as a "microfilter," allowing the secretion of insulin from the capsule but blocking the entrance of antibodies.

The membrane is fabricated with photolithographic techniques commonly used for silicon microchips.

Desai reported the results of short-term testing of the capsule, and the prospects for other micro-devices for drug delivery, today at a meeting of the American Vacuum Society in San Francisco, California. The results will be published in the November issue of IEEE Transactions in Biomedical Engineering.

The next steps are testing the capsule for long-term usage and evaluating the ideal dosage level.


Story Source:

The above story is based on materials provided by National Science Foundation. Note: Materials may be edited for content and length.


Cite This Page:

National Science Foundation. "Biocapsule Can Provide Steady Insulin Supply; Potential Breakthrough For Diabetes Patients." ScienceDaily. ScienceDaily, 31 October 2001. <www.sciencedaily.com/releases/2001/10/011030225614.htm>.
National Science Foundation. (2001, October 31). Biocapsule Can Provide Steady Insulin Supply; Potential Breakthrough For Diabetes Patients. ScienceDaily. Retrieved July 23, 2014 from www.sciencedaily.com/releases/2001/10/011030225614.htm
National Science Foundation. "Biocapsule Can Provide Steady Insulin Supply; Potential Breakthrough For Diabetes Patients." ScienceDaily. www.sciencedaily.com/releases/2001/10/011030225614.htm (accessed July 23, 2014).

Share This




More Health & Medicine News

Wednesday, July 23, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Stone Fruit Listeria Scare Causes Sweeping Recall

Stone Fruit Listeria Scare Causes Sweeping Recall

Newsy (July 22, 2014) The Wawona Packing Company has issued a voluntary recall on the stone fruit it distributes due to a possible Listeria outbreak. Video provided by Newsy
Powered by NewsLook.com
Huge Schizophrenia Study Finds Dozens Of New Genetic Causes

Huge Schizophrenia Study Finds Dozens Of New Genetic Causes

Newsy (July 22, 2014) The 83 new genetic markers could open dozens of new avenues for schizophrenia treatment research. Video provided by Newsy
Powered by NewsLook.com
CDC Head Concerned About a Post-Antibiotic Era

CDC Head Concerned About a Post-Antibiotic Era

AP (July 22, 2014) Sounding alarms about the growing threat of antibiotic resistance, CDC Director Tom Frieden warned Tuesday if the global community does not confront the problem soon, the world will be living in a devastating post-antibiotic era. (July 22) Video provided by AP
Powered by NewsLook.com
Courts Conflicted Over Healthcare Law

Courts Conflicted Over Healthcare Law

AP (July 22, 2014) Two federal appeals courts issued conflicting rulings Tuesday on the legality of the federally-run healthcare exchange that operates in 36 states. (July 22) Video provided by AP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins