Featured Research

from universities, journals, and other organizations

Biocapsule Can Provide Steady Insulin Supply; Potential Breakthrough For Diabetes Patients

Date:
October 31, 2001
Source:
National Science Foundation
Summary:
Pushing the frontiers of drug delivery technology, a biomedical engineer at the University of Illinois at Chicago has developed an implantable capsule that releases a steady supply of insulin to the bloodstream of people with diabetes.

Pushing the frontiers of drug delivery technology, a biomedical engineer at the University of Illinois at Chicago has developed an implantable capsule that releases a steady supply of insulin to the bloodstream of people with diabetes. The biocapsule, developed by Tejal Desai with support from the National Science Foundation (NSF), features two innovations designed to overcome previous obstacles. A biological process allows the capsule to continuously produce insulin, rather than using up a limited supply. The capsule is made of a material designed to overcome the problem of implant rejection.

"The capsule essentially acts as a bioreactor; it contains insulin-secreting cells that borrow nutrients from the body to keep producing insulin indefinitely," Desai said. "As long as the body produces glucose, the cells will respond with insulin."

Desai has also broken new ground by developing a successfully implantable micro-scale device. Tiny devices made with microchip technology have been researched extensively for implantable medical applications, but biocompatibility has been a continuing problem.

To prevent the capsule from being attacked and destroyed by the immune system, Desai developed a silicon membrane covered with tiny uniform pores, each seven nanometers across. The membrane acts as a "microfilter," allowing the secretion of insulin from the capsule but blocking the entrance of antibodies.

The membrane is fabricated with photolithographic techniques commonly used for silicon microchips.

Desai reported the results of short-term testing of the capsule, and the prospects for other micro-devices for drug delivery, today at a meeting of the American Vacuum Society in San Francisco, California. The results will be published in the November issue of IEEE Transactions in Biomedical Engineering.

The next steps are testing the capsule for long-term usage and evaluating the ideal dosage level.


Story Source:

The above story is based on materials provided by National Science Foundation. Note: Materials may be edited for content and length.


Cite This Page:

National Science Foundation. "Biocapsule Can Provide Steady Insulin Supply; Potential Breakthrough For Diabetes Patients." ScienceDaily. ScienceDaily, 31 October 2001. <www.sciencedaily.com/releases/2001/10/011030225614.htm>.
National Science Foundation. (2001, October 31). Biocapsule Can Provide Steady Insulin Supply; Potential Breakthrough For Diabetes Patients. ScienceDaily. Retrieved September 2, 2014 from www.sciencedaily.com/releases/2001/10/011030225614.htm
National Science Foundation. "Biocapsule Can Provide Steady Insulin Supply; Potential Breakthrough For Diabetes Patients." ScienceDaily. www.sciencedaily.com/releases/2001/10/011030225614.htm (accessed September 2, 2014).

Share This




More Health & Medicine News

Tuesday, September 2, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

U.N. Says Ebola Travel Restrictions Will Cause Food Shortage

U.N. Says Ebola Travel Restrictions Will Cause Food Shortage

Newsy (Sep. 2, 2014) The U.N. says the problem is two-fold — quarantine zones and travel restrictions are limiting the movement of both people and food. Video provided by Newsy
Powered by NewsLook.com
Get on Your Bike! London Cycling Popularity Soars Despite Danger

Get on Your Bike! London Cycling Popularity Soars Despite Danger

AFP (Sep. 1, 2014) Wedged between buses, lorries and cars, cycling in London isn't for the faint hearted. Nevertheless the number of people choosing to bike in the British capital has doubled over the past 15 years. Duration: 02:27 Video provided by AFP
Powered by NewsLook.com
Can You Train Your Brain To Eat Healthy?

Can You Train Your Brain To Eat Healthy?

Newsy (Sep. 1, 2014) New research says if you condition yourself to eat healthy foods, eventually you'll crave them instead of junk food. Video provided by Newsy
Powered by NewsLook.com
We've Got Mites Living In Our Faces And So Do You

We've Got Mites Living In Our Faces And So Do You

Newsy (Aug. 30, 2014) A new study suggests 100 percent of adult humans (those over 18 years of age) have Demodex mites living in their faces. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins