Featured Research

from universities, journals, and other organizations

New Islet Cell Transplant May Avoid Surgically Induced Diabetes

Date:
December 24, 2001
Source:
University Of Illinois At Chicago
Summary:
A 36-year-old Chicago man is recovering from a partial pancreatectomy followed by an auto-islet cell transplant at the University of Illinois Medical Center at Chicago. The innovative dual procedure was performed in an effort to alleviate the patient's severe, painful pancreatitis while preserving his ability to secrete insulin and avoid surgically induced diabetes.

A 36-year-old Chicago man is recovering from a partial pancreatectomy followed by an auto-islet cell transplant at the University of Illinois Medical Center at Chicago. The innovative dual procedure was performed in an effort to alleviate the patient's severe, painful pancreatitis while preserving his ability to secrete insulin and avoid surgically induced diabetes.

Related Articles


Surgeons first removed most of the diseased pancreas, leaving behind a small portion of the organ, which may continue to produce enough insulin to support the patient's need to metabolize sugar. However, approximately 30 percent of patients who undergo this surgery develop diabetes. To greatly reduce this risk, a second procedure called auto-islet cell transplantation was carried out using the patient's own pancreatic islet cells.

This combined procedure has been performed in fewer than 50 patients in the United States. A second procedure of this kind is scheduled this week at the University of Illinois Medical Center.

"After a partial pancreatectomy, you never know if the patient will develop diabetes until you find out the hard way," said Dr. Enrico Benedetti, associate professor of surgery at the University of Illinois at Chicago and chief of transplantation at the medical center. "By retaining a small portion of his pancreas, and offering the patient an auto-islet transplant, his chances of developing diabetes are minimal."

After removing approximately 80 percent of the patient's pancreas, physicians prepared the gland by breaking it down with an enzyme that isolates the insulin-producing islet cells. The islet cells were then injected through a catheter into a vein in the patient's liver, where they will graft and function similarly to the removed pancreas. Following a successful transplant, the cells will produce enough insulin to prevent the patient from developing diabetes.

Earlier this year, the medical center opened one of the world's most advanced laboratories for isolating and transplanting the insulin-producing cells of the pancreas in an effort to cure type 1 diabetes, the most severe form of the disease.

"We were able to procure a very large number of high quality islet cells for a successful graft," said Dr. Cristiana Rastellini, director of cell transplant and assistant professor of surgery and immunology at UIC. "I expect that these islets will function very well."

Rastellini is one of the country's leading experts in pancreatic islet cell transplantation.

According to the Society for Surgery of the Alimentary Tract, chronic pancreatitis has an incidence of 5-10 per 100,000 in the United States.

"The patient is doing well," said Dr. Scott Helton, chief of general surgery at UIC who performed the pancreatic resection. "Following his discharge from the hospital, he will be seen in our outpatient clinic, and at that time we will evaluate whether he has insulin independence."

For more information on UIC, visit http://www.uic.edu


Story Source:

The above story is based on materials provided by University Of Illinois At Chicago. Note: Materials may be edited for content and length.


Cite This Page:

University Of Illinois At Chicago. "New Islet Cell Transplant May Avoid Surgically Induced Diabetes." ScienceDaily. ScienceDaily, 24 December 2001. <www.sciencedaily.com/releases/2001/12/011224082903.htm>.
University Of Illinois At Chicago. (2001, December 24). New Islet Cell Transplant May Avoid Surgically Induced Diabetes. ScienceDaily. Retrieved October 24, 2014 from www.sciencedaily.com/releases/2001/12/011224082903.htm
University Of Illinois At Chicago. "New Islet Cell Transplant May Avoid Surgically Induced Diabetes." ScienceDaily. www.sciencedaily.com/releases/2001/12/011224082903.htm (accessed October 24, 2014).

Share This



More Health & Medicine News

Friday, October 24, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

IKEA Desk Converts From Standing to Sitting With One Button

IKEA Desk Converts From Standing to Sitting With One Button

Buzz60 (Oct. 24, 2014) IKEA is out with a new convertible desk that can convert from a sitting desk to a standing one with just the push of a button. Jen Markham explains. Video provided by Buzz60
Powered by NewsLook.com
Ebola Protective Suits Being Made in China

Ebola Protective Suits Being Made in China

AFP (Oct. 24, 2014) A factory in China is busy making Ebola protective suits for healthcare workers and others fighting the spread of the virus. Duration: 00:38 Video provided by AFP
Powered by NewsLook.com
WHO: Millions of Ebola Vaccine Doses by 2015

WHO: Millions of Ebola Vaccine Doses by 2015

AP (Oct. 24, 2014) The World Health Organization said on Friday that millions of doses of two experimental Ebola vaccines could be ready for use in 2015 and five more experimental vaccines would start being tested in March. (Oct. 24) Video provided by AP
Powered by NewsLook.com
Doctor in NYC Quarantined With Ebola

Doctor in NYC Quarantined With Ebola

AP (Oct. 24, 2014) An emergency room doctor who recently returned to the city after treating Ebola patients in West Africa has tested positive for the virus. He's quarantined in a hospital. (Oct. 24) Video provided by AP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins