Featured Research

from universities, journals, and other organizations

Tomato Sauce May Reduce Prostate Cancer Risk

Date:
December 24, 2001
Source:
University Of Illinois At Chicago
Summary:
The adage "an apple a day keeps the doctor away" may be facing stiff competition from tomatoes. Recent research at the University of Illinois at Chicago suggests that lycopene, an antioxidant found in large amounts in tomatoes, may play a significant role in preventing and treating prostate cancer. The findings appear in the Dec. 19 issue of the Journal of the National Cancer Institute.

The adage "an apple a day keeps the doctor away" may be facing stiff competition from tomatoes.

Recent research at the University of Illinois at Chicago suggests that lycopene, an antioxidant found in large amounts in tomatoes, may play a significant role in preventing and treating prostate cancer. The findings appear in the Dec. 19 issue of the Journal of the National Cancer Institute.

Phyllis Bowen, associate professor of human nutrition, along with Dr. Longwen Chen, former research associate, and their UIC colleagues, studied a group of 32 prostate cancer patients who consumed one tomato sauce-based pasta dish daily for three weeks before their scheduled prostatectomies.

Levels of oxidative DNA damage and prostate specific antigen, or PSA (an enzyme that is an important marker for the diagnosis of prostate cancer), were measured before and after the pasta regimen. Previous studies suggest that human prostate tissue is particularly vulnerable to oxidative DNA damage, which occurs when oxygen molecules in the tissue attack the DNA, creating cellular instability. This instability can lead to the formation of malignant tumors.

A high level of lycopene was present in the prostate tissues after the intervention and surgery and oxidative DNA damage was reduced by 28 percent, a statistically significant finding. PSA levels were reduced by 17.5 percent, but the researchers said more studies are needed to determine whether lycopene is responsible for the PSA reduction.

Although other researchers have investigated lycopene in previous studies, this is the first study of its kind yielding statistically significant results with a whole food regimen versus lycopene supplements.

"We're encouraged by the results of this study," Bowen said. "The lower prostate oxidative DNA damage in men consuming tomato sauce suggests a role for tomato sauce and possibly for lycopene in the prevention and treatment of prostate cancer."

However, Bowen noted, this study had a small sample size. A larger study is in progress involving patients with and without diagnosed prostate cancer.

According to the American Cancer Society, prostate cancer is the second leading cause of cancer-related deaths in American men (lung cancer ranks first). At the start of this year, the society estimated that 198,000 men would be diagnosed with prostate cancer, with 31,500 deaths.

For more information about UIC, visit http://www.uic.edu


Story Source:

The above story is based on materials provided by University Of Illinois At Chicago. Note: Materials may be edited for content and length.


Cite This Page:

University Of Illinois At Chicago. "Tomato Sauce May Reduce Prostate Cancer Risk." ScienceDaily. ScienceDaily, 24 December 2001. <www.sciencedaily.com/releases/2001/12/011224083820.htm>.
University Of Illinois At Chicago. (2001, December 24). Tomato Sauce May Reduce Prostate Cancer Risk. ScienceDaily. Retrieved October 23, 2014 from www.sciencedaily.com/releases/2001/12/011224083820.htm
University Of Illinois At Chicago. "Tomato Sauce May Reduce Prostate Cancer Risk." ScienceDaily. www.sciencedaily.com/releases/2001/12/011224083820.htm (accessed October 23, 2014).

Share This



More Health & Medicine News

Thursday, October 23, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Orthodontist Mom Jennifer Salzer on the Best Time for Braces

Orthodontist Mom Jennifer Salzer on the Best Time for Braces

Working Mother (Oct. 22, 2014) Is your child ready? Video provided by Working Mother
Powered by NewsLook.com
U.S. Issues Ebola Travel Restrictions, Are Visa Bans Next?

U.S. Issues Ebola Travel Restrictions, Are Visa Bans Next?

Newsy (Oct. 22, 2014) Now that the U.S. is restricting travel from West Africa, some are dropping questions about a travel ban and instead asking about visa bans. Video provided by Newsy
Powered by NewsLook.com
US to Track Everyone Coming from Ebola Nations

US to Track Everyone Coming from Ebola Nations

AP (Oct. 22, 2014) Stepping up their vigilance against Ebola, federal authorities said Wednesday that everyone traveling into the US from Ebola-stricken nations will be monitored for symptoms for 21 days. (Oct. 22) Video provided by AP
Powered by NewsLook.com
Doctors Help Paralysed Man Walk Again, Patient in Disbelief

Doctors Help Paralysed Man Walk Again, Patient in Disbelief

AFP (Oct. 22, 2014) Polish doctors describe how they helped a paralysed man walk again, with the patient in disbelief at the return of sensation to his legs. Duration: 1:04 Video provided by AFP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins