Featured Research

from universities, journals, and other organizations

Clinical Trials For "Cytobrush" Detection Technique Show Promise In Fight Against Oral Cancer

Date:
January 8, 2002
Source:
University Of Pennsylvania
Summary:
Dentists now have an easy-to-use, pain-free way to detect oral cancer at its earliest stages. Called the cytobrush biopsy, the technique underwent clinical trials at the University of Pennsylvania School of Dental Medicine that showed it to be a significant advance over previous cytology (PAP smear-type) tests.

PHILADELPHIA – Dentists now have an easy-to-use, pain-free way to detect oral cancer at its earliest stages. Called the cytobrush biopsy, the technique underwent clinical trials at the University of Pennsylvania School of Dental Medicine that showed it to be a significant advance over previous cytology (PAP smear-type) tests.

"Early detection is our most important weapon in our fight against oral cancer," said Martin S. Greenberg, DDS, professor and chairman of oral medicine at Penn and chief of oral medicine at Penn Medical Center. "The survival rate for this prevalent cancer is only 50 percent overall, but survival rates increase to greater than 80 percent if the cancer is found early."

With the cytobrush technique, developed by engineers and cytologists at Oral Scan Systems, a New York-based health devices company, a dentist who finds an area of concern runs a small round brush – similar to a mascara wand – over the suspicious lesion.

"The bristles are like those on a toothbrush," Greenberg said. "They can penetrate and get a better sampling of cells than the old scraping technique."

The sample is sent to a lab where it is scanned using advanced computer technology. Suspicious slides are tagged for further evaluation by a technician. The computer is so exacting, Greenberg said, that the false negative rate, which was as high as 30 percent using the scraping method, dropped to 0 percent in the clinical trials. Penn conducted clinical trials on the cytobrush for more than a year.

"Oral cancer is a nasty disease," Greenberg said. "The best way to avoid it is prevention; no smoking, no excessive alcohol and regular oral exams to detect early suspicious lesions."

Each year in the United States, 30,000 new cases of oral and oropharyngeal cancer are found and 8,500 people die from the disease. Survivors of advanced oral cancer, which is a major cause of death worldwide, have significant physical and psychological disability, he said.


Story Source:

The above story is based on materials provided by University Of Pennsylvania. Note: Materials may be edited for content and length.


Cite This Page:

University Of Pennsylvania. "Clinical Trials For "Cytobrush" Detection Technique Show Promise In Fight Against Oral Cancer." ScienceDaily. ScienceDaily, 8 January 2002. <www.sciencedaily.com/releases/2002/01/020107075232.htm>.
University Of Pennsylvania. (2002, January 8). Clinical Trials For "Cytobrush" Detection Technique Show Promise In Fight Against Oral Cancer. ScienceDaily. Retrieved September 22, 2014 from www.sciencedaily.com/releases/2002/01/020107075232.htm
University Of Pennsylvania. "Clinical Trials For "Cytobrush" Detection Technique Show Promise In Fight Against Oral Cancer." ScienceDaily. www.sciencedaily.com/releases/2002/01/020107075232.htm (accessed September 22, 2014).

Share This



More Health & Medicine News

Monday, September 22, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Liberia Pleads for Help to Fight Ebola

Liberia Pleads for Help to Fight Ebola

AP (Sep. 22, 2014) Liberia's finance minister is urging the international community to quickly follow through on pledges of cash to battle Ebola. Bodies are piling up in the capital Monrovia as the nation awaits more help. (Sept. 22) Video provided by AP
Powered by NewsLook.com
Ebola Doctor Says Border Controls Critical

Ebola Doctor Says Border Controls Critical

AP (Sep. 22, 2014) A Florida doctor who helped fight the expanding Ebola outbreak in West Africa says the disease can be stopped, but only if nations quickly step up their response and make border control a priority. (Sept. 22) Video provided by AP
Powered by NewsLook.com
Global Ebola Aid Increasing But Critics Say It's Late

Global Ebola Aid Increasing But Critics Say It's Late

Newsy (Sep. 21, 2014) More than 100 tons of medical supplies were sent to West Africa on Saturday, but aid workers say the global response is still sluggish. Video provided by Newsy
Powered by NewsLook.com
Sierra Leone in Lockdown to Control Ebola

Sierra Leone in Lockdown to Control Ebola

AP (Sep. 21, 2014) Sierra Leone residents remained in lockdown on Saturday as part of a massive effort to confine millions of people to their homes in a bid to stem the biggest Ebola outbreak in history. (Sept. 20) Video provided by AP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins