Featured Research

from universities, journals, and other organizations

International Space Station Research To Study Treatments For Liver Ailments

Date:
January 18, 2002
Source:
National Aeronautics And Space Administration
Summary:
NASA has signed an agreement with StelSys LLC, Baltimore, to fly experiments on the International Space Station that will compare human liver-cell function in space with that on Earth. This research could aid in StelSys' development of treatment for people in need of liver transplants.

NASA has signed an agreement with StelSys LLC, Baltimore, to fly experiments on the International Space Station that will compare human liver-cell function in space with that on Earth. This research could aid in StelSys' development of treatment for people in need of liver transplants.

Related Articles


The research primarily will evaluate how human liver cells process medicine in space and will add to further ground-based research. Space Shuttle Discovery will deliver the research equipment on mission STS- 111 scheduled for launch in May 2002.

"This will be an excellent start for commercial use of space technology," said Dr. Neal Pellis, Chief, Biological Systems Office, at NASA's Johnson Space Center in Houston. "We hope this is the first of many." The agreement to fly experiments in space comes just one year after a groundbreaking licensing agreement between NASA and StelSys intended to explore a new frontier in biotechnology. The agreement focuses on the development of commercial medical products and services using NASA's Bioreactor technology in four areas, including development of a liver-assist device and a method for producing liver-cell biomolecules and metabolites.

"Space is the gold-standard environment for this cutting-edge cell research. Only in space, a true microgravity environment, will we be able to isolate and study each of the individual factors impacting cell function. This will allow us to refine and then optimize ground-based Bioreactor research," said Dr. Fisk Johnson, president of Wisconsin-based Fisk Ventures and co-founder of StelSys.

Utilizing the Bioreactor technology over the past year, StelSys scientists have discovered a unique procedure to accomplish long-term culturing of liver cells, which allows the cells to maintain liver-specific functions for at least a week, compared to only a day using traditional methods. In addition, they have developed a prototype of a novel "bioartificial" liver.

NASA invented the rotating Bioreactor as a way to study the impact of microgravity on cellular growth on Earth and in space. Traditional cell-growth research often produces single-cell, pancake-like cultures which quickly lose normal cell function. The Bioreactor works by gently spinning a fluid medium filled with cells. The spinning motion neutralizes most of gravity's effects, creating a near-weightless environment that allows cells to grow more freely, in a three-dimensional manner.

"StelSys is committed to research with real-world benefit to people. Our recent discoveries could lead to better, earlier drug-candidate screening, which would speed up drug development by pharmaceutical companies, and importantly, to a longer life for the 25,000 people every year waiting for a life-saving liver transplant," said Dr. Paul Silber, president of StelSys. This research is being conducted under an agreement with NASA's Office of Biological and Physical Research, Washington. The office is responsible for basic and applied research using the low-gravity environment of space.

StelSys LLC is a biotechnology research company formed to develop and commercialize real-world applications of the NASA Bioreactor technology. The company maintains a core team of researchers with expertise in cell biology and chemical engineering.

Additional information concerning this research is available via the Internet at:

http://spaceresearch.nasa.gov/


Story Source:

The above story is based on materials provided by National Aeronautics And Space Administration. Note: Materials may be edited for content and length.


Cite This Page:

National Aeronautics And Space Administration. "International Space Station Research To Study Treatments For Liver Ailments." ScienceDaily. ScienceDaily, 18 January 2002. <www.sciencedaily.com/releases/2002/01/020118075705.htm>.
National Aeronautics And Space Administration. (2002, January 18). International Space Station Research To Study Treatments For Liver Ailments. ScienceDaily. Retrieved October 30, 2014 from www.sciencedaily.com/releases/2002/01/020118075705.htm
National Aeronautics And Space Administration. "International Space Station Research To Study Treatments For Liver Ailments." ScienceDaily. www.sciencedaily.com/releases/2002/01/020118075705.htm (accessed October 30, 2014).

Share This



More Health & Medicine News

Thursday, October 30, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Mind-Controlled Prosthetic Arm Restores Amputee Dexterity

Mind-Controlled Prosthetic Arm Restores Amputee Dexterity

Reuters - Innovations Video Online (Oct. 29, 2014) A Swedish amputee who became the first person to ever receive a brain controlled prosthetic arm is able to manipulate and handle delicate objects with an unprecedented level of dexterity. The device is connected directly to his bone, nerves and muscles, giving him the ability to control it with his thoughts. Matthew Stock reports. Video provided by Reuters
Powered by NewsLook.com
Google To Use Nanoparticles, Wearables To Detect Disease

Google To Use Nanoparticles, Wearables To Detect Disease

Newsy (Oct. 29, 2014) Google X wants to improve modern medicine with nanoparticles and a wearable device. It's all an attempt to tackle disease detection and prevention. Video provided by Newsy
Powered by NewsLook.com
Can Drinking Milk Lead To Early Death?

Can Drinking Milk Lead To Early Death?

Newsy (Oct. 29, 2014) Researchers in Sweden released a study showing heavy milk drinkers face an increased mortality risk from a variety of causes. Video provided by Newsy
Powered by NewsLook.com
Obama: The US Will Not 'run and Hide' From Ebola

Obama: The US Will Not 'run and Hide' From Ebola

AP (Oct. 29, 2014) Surrounded by health care workers in the White House East Room, President Barack Obama said the U.S. will likely see additional Ebola cases in the weeks ahead. But he said the nation can't seal itself off in the fight against the disease. (Oct. 29) Video provided by AP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins