Featured Research

from universities, journals, and other organizations

Race Influences Outcome Of Liver Transplants, According To Hopkins Study

Date:
January 25, 2002
Source:
Johns Hopkins Medical Institutions
Summary:
African Americans and Asians have a worse outcome than white Americans and Hispanics after liver transplantation, both in terms of graft rejection and survival, according to a new Hopkins-led study reported in the Jan. 26 issue of The Lancet.

African Americans and Asians have a worse outcome than white Americans and Hispanics after liver transplantation, both in terms of graft rejection and survival, according to a new Hopkins-led study reported in the Jan. 26 issue of The Lancet.

Related Articles


Scientists analyzed data on age, sex, race, blood group, and cause of death of donors and recipients from the United Network of Organ Sharing (UNOS) registry for all liver transplants done between 1988 and 1996 in the United States.

"Our results show that outcomes two years after surgery were considerably lower for African Americans and Asians than for white Americans," says Paul Thuluvath, M.D., associate professor of medicine and medical director of liver transplantation in the Division of Gastroenterology and Hepatology at Hopkins and lead author of the paper.

While the low outcomes for Asians are influenced by the number of patients with hepatitis B, the cause for low survival in African Americans remains unclear. What is clear, says Thuluvath, is that more studies need to be done to determine why African Americans are faring less well than other races.

"Until then, the reasons for poor survival in African Americans will remain speculative," says Thuluvath.

The scientists report that two-year graft survival for African Americans (601 of 884, 68 percent) and Asians (266 of 416, 64 percent) was significantly lower than white Americans (8703 of 11,762, 74 percent) and Hispanics (878 or 1220, 72 percent). Likewise, two-year survival was significantly lower for African Americans (74 percent) and Asians (69 percent) than for white Americans (83 percent) and Hispanics (79 percent).

"In terms of risk, African Americans are 34 percent more likely to die from liver transplant than white Americans," says Thuluvath. "And Asians had an increased risk profile of 25% compared with white Americans."

Thuluvath and colleagues are now investigating claims that poor survival in African Americans is due to such socioeconomic factors as poor compliance with postoperative care, and lack of insurance benefits. Preliminary data on 500 liver transplant patients treated at Hopkins suggest that socioeconomic factors are not at fault, and Thuluvath is analyzing more than 30,000 liver transplant cases in the United Network of Organ Sharing to determine the extent to which socioeconomic factors can be implicated.

Other authors are Sateesh Nair, M.D., and Joseph Eustace, M.D., of Johns Hopkins.


Story Source:

The above story is based on materials provided by Johns Hopkins Medical Institutions. Note: Materials may be edited for content and length.


Cite This Page:

Johns Hopkins Medical Institutions. "Race Influences Outcome Of Liver Transplants, According To Hopkins Study." ScienceDaily. ScienceDaily, 25 January 2002. <www.sciencedaily.com/releases/2002/01/020125073659.htm>.
Johns Hopkins Medical Institutions. (2002, January 25). Race Influences Outcome Of Liver Transplants, According To Hopkins Study. ScienceDaily. Retrieved October 25, 2014 from www.sciencedaily.com/releases/2002/01/020125073659.htm
Johns Hopkins Medical Institutions. "Race Influences Outcome Of Liver Transplants, According To Hopkins Study." ScienceDaily. www.sciencedaily.com/releases/2002/01/020125073659.htm (accessed October 25, 2014).

Share This



More Health & Medicine News

Saturday, October 25, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Texas Nurse Nina Pham Cured of Ebola

Texas Nurse Nina Pham Cured of Ebola

AFP (Oct. 25, 2014) — An American nurse who contracted Ebola while caring for a Liberian patient in Texas has been declared free of the virus and will leave the hospital. Duration: 01:01 Video provided by AFP
Powered by NewsLook.com
IKEA Desk Converts From Standing to Sitting With One Button

IKEA Desk Converts From Standing to Sitting With One Button

Buzz60 (Oct. 24, 2014) — IKEA is out with a new convertible desk that can convert from a sitting desk to a standing one with just the push of a button. Jen Markham explains. Video provided by Buzz60
Powered by NewsLook.com
Ebola Protective Suits Being Made in China

Ebola Protective Suits Being Made in China

AFP (Oct. 24, 2014) — A factory in China is busy making Ebola protective suits for healthcare workers and others fighting the spread of the virus. Duration: 00:38 Video provided by AFP
Powered by NewsLook.com
WHO: Millions of Ebola Vaccine Doses by 2015

WHO: Millions of Ebola Vaccine Doses by 2015

AP (Oct. 24, 2014) — The World Health Organization said on Friday that millions of doses of two experimental Ebola vaccines could be ready for use in 2015 and five more experimental vaccines would start being tested in March. (Oct. 24) Video provided by AP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:

Strange & Offbeat Stories

 

Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins