Featured Research

from universities, journals, and other organizations

Yale Study Shows 25 Percent Of Obese Children Are At High Risk For Developing Diabetes

Date:
March 19, 2002
Source:
Yale University
Summary:
Twenty five percent of obese children and 21 percent of obese adolescents tested by Yale researchers were glucose intolerant and at high risk for developing diabetes, according to an article published Thursday in the New England Journal of Medicine.

New Haven, Conn. – Twenty five percent of obese children and 21 percent of obese adolescents tested by Yale researchers were glucose intolerant and at high risk for developing diabetes, according to an article published Thursday in the New England Journal of Medicine.

Related Articles


Sonia Caprio, associate professor of endocrinology and pediatrics at Yale School of Medicine and senior author of the article, said the study was in response to the epidemic of childhood obesity in the United States, along with an accompanying increase in the prevalence of type 2 diabetes among children and adolescents.

Type One diabetes is usually first diagnosed in young children. Type 2, or, adult onset diabetes, often does not manifest itself until a person is middle aged or elderly.

"Most of these children are at high risk for type 2 diabetes," Caprio said. "And, if they develop diabetes before the age of 20, they face a lifetime of being at very high risk for complications from diabetes."

A glucose tolerance test evaluates the body’s capacity to metabolize glucose, based upon the ability of the liver to absorb and store excess glucose as glycogen.

Caprio and her co-researchers looked at a multi-ethnic group of 167 severely obese children and adolescents. All underwent a two-hour oral glucose tolerance test during which glucose, insulin and C-peptide levels were measured.

The glucose intolerance was as prevalent among Caucasians as it was among African American and Hispanic children, who traditionally have higher rates of diabetes. The condition also was more prevalent among girls than boys.

Impaired glucose tolerance was detected in 25 percent of the children four to 10 years of age, and 21 percent of the adolescents 11 to 18 years of age. Silent type 2 diabetes, which means the persons are not aware they are diabetic, was identified in four of the adolescents. Two were Hispanic and two were African American. In addition, three of the children during the four-year course of the study progressed from glucose intolerance to diabetes.

Fourteen of the girls had polycystic ovary syndrome, which causes symptoms such as menstrual irregularities, hirsutism due to high androgen levels, and, over time, infertility, as well as cysts on their ovaries. The syndrome also is associated with darkening and thickening of the skin around the neck and under the arms.

Possible long term complications from diabetes include premature artherosclerosis, often affecting the legs and leading to ulcers of the feet; early coronary artery disease; kidney disorders; eye disorders, sometimes leading to blindness, and nerve problems.

Co-authors included Ranjana Sinha, M.D., Gene Fisch, Barbara Teague, R.N., William Tamborlane, M.D., Bruna Banyas, R.N., Karin Allen, R.N., Mary Savoye, Vera Rieger, M.D., Sara Taksali, Gina Barbetta, Robert Sherwin, M.D., and Sonia Caprio, M.D.

The study was funded by the National Institute of Child Health and Human Development of the National Institutes of Health and the National Center for Research Resources (NCRR). The NCRR awarded grants to Yale for two General Clinical Research Centers that host adult and child studies. NCRR funding provides NIH-supported investigators with access to specialized basic and clinical research facilities, technologies, instrumentation, biomaterials, animal models, genetic stocks, and more.


Story Source:

The above story is based on materials provided by Yale University. Note: Materials may be edited for content and length.


Cite This Page:

Yale University. "Yale Study Shows 25 Percent Of Obese Children Are At High Risk For Developing Diabetes." ScienceDaily. ScienceDaily, 19 March 2002. <www.sciencedaily.com/releases/2002/03/020314080503.htm>.
Yale University. (2002, March 19). Yale Study Shows 25 Percent Of Obese Children Are At High Risk For Developing Diabetes. ScienceDaily. Retrieved December 18, 2014 from www.sciencedaily.com/releases/2002/03/020314080503.htm
Yale University. "Yale Study Shows 25 Percent Of Obese Children Are At High Risk For Developing Diabetes." ScienceDaily. www.sciencedaily.com/releases/2002/03/020314080503.htm (accessed December 18, 2014).

Share This


More From ScienceDaily



More Health & Medicine News

Thursday, December 18, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Kids Die While Under Protective Services

Kids Die While Under Protective Services

AP (Dec. 18, 2014) As part of a six-month investigation of child maltreatment deaths, the AP found that hundreds of deaths from horrific abuse and neglect could have been prevented. AP's Haven Daley reports. (Dec. 18) Video provided by AP
Powered by NewsLook.com
UN: Up to One Million Facing Hunger in Ebola-Hit Countries

UN: Up to One Million Facing Hunger in Ebola-Hit Countries

AFP (Dec. 17, 2014) Border closures, quarantines and crop losses in West African nations battling the Ebola virus could lead to as many as one million people going hungry, UN food agencies said on Wednesday. Duration: 00:52 Video provided by AFP
Powered by NewsLook.com
When You Lose Weight, This Is Where The Fat Goes

When You Lose Weight, This Is Where The Fat Goes

Newsy (Dec. 17, 2014) Can fat disappear into thin air? New research finds that during weight loss, over 80 percent of a person's fat molecules escape through the lungs. Video provided by Newsy
Powered by NewsLook.com
Why Your Boss Should Let You Sleep In

Why Your Boss Should Let You Sleep In

Newsy (Dec. 17, 2014) According to research out of the University of Pennsylvania, waking up for work is the biggest factor that causes Americans to lose sleep. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins