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Muscular Dystrophy Mouse Model Yields Potential Growth Factor Treatment

Date:
May 23, 2002
Source:
NIH/National Institute Of Arthritis And Musculoskeletal And Skin Diseases
Summary:
An altered mouse model of Duchenne muscular dystrophy, developed to have high levels of insulin-like growth factor I (IGF-I), has shown increases in muscle mass of at least 40 percent and other changes that could herald a possible treatment for secondary symptoms of the disease in humans. The new mouse, developed with support from the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) and the Muscular Dystrophy Association, has also resulted in reduced amounts of muscle-replacing fibrous tissue and enhanced biological pathways associated with muscle regeneration.

An altered mouse model of Duchenne muscular dystrophy, developed to have high levels of insulin-like growth factor I (IGF-I), has shown increases in muscle mass of at least 40 percent and other changes that could herald a possible treatment for secondary symptoms of the disease in humans. The new mouse, developed with support from the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) and the Muscular Dystrophy Association, has also resulted in reduced amounts of muscle-replacing fibrous tissue and enhanced biological pathways associated with muscle regeneration.


Story Source:

The above story is based on materials provided by NIH/National Institute Of Arthritis And Musculoskeletal And Skin Diseases. Note: Materials may be edited for content and length.


Cite This Page:

NIH/National Institute Of Arthritis And Musculoskeletal And Skin Diseases. "Muscular Dystrophy Mouse Model Yields Potential Growth Factor Treatment." ScienceDaily. ScienceDaily, 23 May 2002. <www.sciencedaily.com/releases/2002/05/020523075505.htm>.
NIH/National Institute Of Arthritis And Musculoskeletal And Skin Diseases. (2002, May 23). Muscular Dystrophy Mouse Model Yields Potential Growth Factor Treatment. ScienceDaily. Retrieved April 21, 2014 from www.sciencedaily.com/releases/2002/05/020523075505.htm
NIH/National Institute Of Arthritis And Musculoskeletal And Skin Diseases. "Muscular Dystrophy Mouse Model Yields Potential Growth Factor Treatment." ScienceDaily. www.sciencedaily.com/releases/2002/05/020523075505.htm (accessed April 21, 2014).

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