Featured Research

from universities, journals, and other organizations

Einstein Researchers Develop Blood Substitute That Shows Promise For Use In Emergency Situations

Date:
December 2, 2003
Source:
Albert Einstein College Of Medicine
Summary:
An artificial blood product developed by researchers at the Albert Einstein College of Medicine is showing great promise in ongoing clinical trials in Stockholm, Sweden - the first time that a blood substitute has ever been used successfully in humans.

An artificial blood product developed by researchers at the Albert Einstein College of Medicine is showing great promise in ongoing clinical trials in Stockholm, Sweden - the first time that a blood substitute has ever been used successfully in humans. The Einstein researchers - whose work is supported by $2.2 million in grants from the National Institutes of Health and the U.S. Army -- are also fine-tuning a powder version of the substitute that can be reconstituted for use as needed with the simple addition of water.

An October 23rd BBC News article describing the Stockholm trials quoted one enthusiastic researcher, Dr. Pierre LaFolie, chief physician at Karolinska Hospital in Sweden, "If this really works all the way, then mankind will have taken a big step forward."

The leader in developing the blood product is Dr. Seetharama Acharya, professor of medicine and of biophysics and physiology at Einstein. Using blood from donated supplies - whose shelf life for use in transfusions is generally limited to 42 days - Dr. Acharya developed the technology that makes the hemoglobin removed from "old" red blood cells suitable for use in transfusions.

"With our blood product, the issue of blood typing is removed," says Dr. Acharya. "Patients with any blood type can receive the artificial blood, which then transports oxygen through the body to help limit damage at a time when loss of blood can lead to death."

"When time is of the essence - on the battlefield, for example - being able to provide a blood transfusion without the need for typing can save critical seconds," said Dr. Joel Friedman, professor of biophysics and physiology at Einstein and principal investigator of the NIH-funded project. "The same could be said of an accident scene with multiple injuries or emergency surgeries. Our product offers a viable bridge during emergency situations for providing a blood product that complements the individual's own blood while transporting oxygen vital to the person's well-being."

Initial clinical trials are taking place at Sweden's Karolinska Hospital. The product being studied was produced by a pharmaceutical company that has licensed the technology for making the blood substitute from its Einstein inventors. Thus far, eight patients have been tested, with none demonstrating signs either of rejection or of any of the potential deleterious side effects, such as hypertension, that have been observed with many of the earlier candidates for use as blood substitutes.

The study also showed that this artificial blood transported even more oxygen throughout the body than real blood, which can help to limit tissue damage associated with oxygen deprivation.

"The implications for the use of a blood substitute like ours could be far-reaching," said Dr. Friedman. "We're very excited about the many potential uses for this product and, using the support from the NIH and U.S. Army, plan to fine-tune and perfect it through further testing that will ultimately lead to its use in real-life emergency situations."


Story Source:

The above story is based on materials provided by Albert Einstein College Of Medicine. Note: Materials may be edited for content and length.


Cite This Page:

Albert Einstein College Of Medicine. "Einstein Researchers Develop Blood Substitute That Shows Promise For Use In Emergency Situations." ScienceDaily. ScienceDaily, 2 December 2003. <www.sciencedaily.com/releases/2003/12/031202065239.htm>.
Albert Einstein College Of Medicine. (2003, December 2). Einstein Researchers Develop Blood Substitute That Shows Promise For Use In Emergency Situations. ScienceDaily. Retrieved October 1, 2014 from www.sciencedaily.com/releases/2003/12/031202065239.htm
Albert Einstein College Of Medicine. "Einstein Researchers Develop Blood Substitute That Shows Promise For Use In Emergency Situations." ScienceDaily. www.sciencedaily.com/releases/2003/12/031202065239.htm (accessed October 1, 2014).

Share This



More Health & Medicine News

Wednesday, October 1, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Pregnancy Spacing Could Have Big Impact On Autism Risks

Pregnancy Spacing Could Have Big Impact On Autism Risks

Newsy (Oct. 1, 2014) A new study says children born less than one year and more than five years after a sibling can have an increased risk for autism. Video provided by Newsy
Powered by NewsLook.com
Robotic Hair Restoration

Robotic Hair Restoration

Ivanhoe (Oct. 1, 2014) A new robotic procedure is changing the way we transplant hair. The ARTAS robot leaves no linear scarring and provides more natural results. Video provided by Ivanhoe
Powered by NewsLook.com
Insertable Cardiac Monitor

Insertable Cardiac Monitor

Ivanhoe (Oct. 1, 2014) A heart monitor the size of a paperclip that can save your life. The “Reveal Linq” allows a doctor to monitor patients with A-Fib on a continuous basis for up to 3 years! Video provided by Ivanhoe
Powered by NewsLook.com
Attacking Superbugs

Attacking Superbugs

Ivanhoe (Oct. 1, 2014) Two weapons hospitals can use to attack superbugs. Scientists in Ireland created a new gel resistant to superbugs, and a robot that can disinfect a room in minutes. Video provided by Ivanhoe
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins