Featured Research

from universities, journals, and other organizations

UT Southwestern Researchers Study Benefit Of Exercise, Medication On Depression

Date:
February 5, 2004
Source:
University Of Texas Southwestern Medical Center At Dallas
Summary:
Exercise is known to help relieve stress, boost spirits and fight symptoms of depression. But can a regular exercise routine combined with targeted medications actually cure major depressive disorder?

DALLAS – Feb. 2, 2004 – Exercise is known to help relieve stress, boost spirits and fight symptoms of depression. But can a regular exercise routine combined with targeted medications actually cure major depressive disorder?

UT Southwestern researchers, partnering with The Cooper Institute in Dallas, hope to find an answer by studying how individuals treated with certain antidepressant medications respond to supervised exercise.

The study – funded by a $2.4 million, four-year grant from the National Institute for Mental Health (NIMH) – focuses on individuals taking selective serotonin re-uptake inhibitors, (SSRIs), who also participate in a 24-week exercise program. SSRIs are the most prescribed medications for depression and include such drugs as Prozac, Zoloft, Paxil and Celexa.

"The majority of people who start on an SSRI feel better after they begin treatment, but they still don't feel completely well or as good as they did before they became depressed," said Dr. Madhukar Trivedi, associate professor of psychiatry and head of the depression and anxiety disorders program at UT Southwestern. "While their symptoms are reduced, they seldom get to full remission."

Preliminary results indicate positive responses from patients, said Dr. Trivedi, who received the NIMH grant after being awarded a $100,000 grant from the National Alliance for Research on Schizophrenia and Depression earlier in 2003, which allowed him to gather pilot data for the study.

"Exercise may have a synergistic or additive effect combined with anti-depressant medication, which could provide significant benefits over singular treatment methods," he said. "There also is some suggestion that exercise can change neurotransmitter levels, like those of serotonin, in the brain. These changes in neurochemicals have been reported to help improve symptoms of depression. Plus, we already know that exercise can have a positive effect on a person's overall health and well-being.

"The goal of this study is to determine if exercise can help augment the SSRI treatment to the point of reducing all the symptoms of depression."

UT Southwestern currently is enrolling study participants between the ages of 18 and 65 who have been taking an SSRI for eight to 12 weeks and are continuing to experience symptoms of depression. Interested persons should call 214-648-0173. Eligible participants will begin an exercise program at The Cooper Institute, located at 12230 Preston Road, as well as being trained on how to exercise at home.


Story Source:

The above story is based on materials provided by University Of Texas Southwestern Medical Center At Dallas. Note: Materials may be edited for content and length.


Cite This Page:

University Of Texas Southwestern Medical Center At Dallas. "UT Southwestern Researchers Study Benefit Of Exercise, Medication On Depression." ScienceDaily. ScienceDaily, 5 February 2004. <www.sciencedaily.com/releases/2004/02/040203233706.htm>.
University Of Texas Southwestern Medical Center At Dallas. (2004, February 5). UT Southwestern Researchers Study Benefit Of Exercise, Medication On Depression. ScienceDaily. Retrieved April 16, 2014 from www.sciencedaily.com/releases/2004/02/040203233706.htm
University Of Texas Southwestern Medical Center At Dallas. "UT Southwestern Researchers Study Benefit Of Exercise, Medication On Depression." ScienceDaily. www.sciencedaily.com/releases/2004/02/040203233706.htm (accessed April 16, 2014).

Share This



More Health & Medicine News

Wednesday, April 16, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Ebola Outbreak Now Linked To 121 Deaths

Ebola Outbreak Now Linked To 121 Deaths

Newsy (Apr. 15, 2014) The ebola virus outbreak in West Africa is now linked to 121 deaths. Health officials fear the virus will continue to spread in urban areas. Video provided by Newsy
Powered by NewsLook.com
Cognitive Function: Is It All Downhill From Age 24?

Cognitive Function: Is It All Downhill From Age 24?

Newsy (Apr. 15, 2014) A new study out of Canada says cognitive motor performance begins deteriorating around age 24. Video provided by Newsy
Powered by NewsLook.com
How Mt. Everest Helped Scientists Research Diabetes

How Mt. Everest Helped Scientists Research Diabetes

Newsy (Apr. 15, 2014) British researchers were able to use Mount Everest's low altitudes to study insulin resistance. They hope to find ways to treat diabetes. Video provided by Newsy
Powered by NewsLook.com
Carpenter's Injury Leads To Hundreds Of 3-D-Printed Hands

Carpenter's Injury Leads To Hundreds Of 3-D-Printed Hands

Newsy (Apr. 14, 2014) Richard van As lost all fingers on his right hand in a woodworking accident. Now, he's used the incident to create a prosthetic to help hundreds. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins