Featured Research

from universities, journals, and other organizations

Cells From Adult Bone Marrow Can Be Converted Into Brain Stem Cells For Transplantation

Date:
May 3, 2004
Source:
American Academy Of Neurology
Summary:
New research shows that cells taken from adult human bone marrow can be converted into brain stem cells that meet the criteria for transplantation into the brain.

SAN FRANCISCO – Hope for people with Parkinson's disease, Alzheimer's disease, stroke and other neurodegenerative diseases may ultimately come from their own bodies. Research that will be presented at the American Academy of Neurology 56th Annual Meeting in San Francisco, Calif., April 24 – May 1, 2004, shows that cells taken from adult human bone marrow can be converted into brain stem cells that meet the criteria for transplantation into the brain.

Related Articles


"It's exciting to think that some day a person with Alzheimer's disease could use their own bone marrow to create brain cells that could potentially restore their functioning and make up for cells that were lost," said study author and neurologist Alexander Storch, MD, of the University of Ulm in Ulm, Germany.

Use of the cells from adult human bone marrow, called stromal cells, eliminates the ethical and logistical issues that arise with the use of cells from fetal tissue, Storch said. And use of cells from bone marrow that would be converted and transplanted into the same person's brain eliminates ethical issues and immune-system problems that can arise when the body rejects cells from an outside source.

For the study, the researchers took the adult human bone marrow stromal cells and cultured them with growth factors.

Other benefits of this process are that the cells can be converted quickly – within a few weeks – and a small amount of bone marrow can produce a large amount of converted cells, Storch said.

More research is needed before the converted cells can be tested in humans. Animal studies are under way to explore the regenerative potential of the converted cells in animal models of acute and chronic neurodegenerative disorders, such as stroke and Parkinson's disease. The researchers also need to determine the best way to administer the cells into the brain.

###The study was supported by the Interdisciplinary Center for Clinical Research, Ulm, the Polish-German Cooperation in Neuroscience Program, and the Landesstiftung Baden-Wόrttemberg.

The American Academy of Neurology, an association of more than 18,000 neurologists and neuroscience professionals, is dedicated to improving patient care through education and research. A neurologist is a doctor with specialized training in diagnosing, treating and managing disorders of the brain and nervous system such as stroke, Alzheimer's disease, epilepsy, Parkinson's disease, autism and multiple sclerosis.

For more information about the American Academy of Neurology, visit its website at http://www.aan.com/press/.


Story Source:

The above story is based on materials provided by American Academy Of Neurology. Note: Materials may be edited for content and length.


Cite This Page:

American Academy Of Neurology. "Cells From Adult Bone Marrow Can Be Converted Into Brain Stem Cells For Transplantation." ScienceDaily. ScienceDaily, 3 May 2004. <www.sciencedaily.com/releases/2004/05/040503055935.htm>.
American Academy Of Neurology. (2004, May 3). Cells From Adult Bone Marrow Can Be Converted Into Brain Stem Cells For Transplantation. ScienceDaily. Retrieved April 25, 2015 from www.sciencedaily.com/releases/2004/05/040503055935.htm
American Academy Of Neurology. "Cells From Adult Bone Marrow Can Be Converted Into Brain Stem Cells For Transplantation." ScienceDaily. www.sciencedaily.com/releases/2004/05/040503055935.htm (accessed April 25, 2015).

Share This


More From ScienceDaily



More Health & Medicine News

Saturday, April 25, 2015

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

85 Killed in Niger by Meningitis Since Start of Year

85 Killed in Niger by Meningitis Since Start of Year

AFP (Apr. 24, 2015) — A meningitis outbreak in Niger has killed 85 people since the start of the year prompting authorities to close schools in the capital Niamey until Monday. Video provided by AFP
Powered by NewsLook.com
C-Section Births a Trend in Brazil

C-Section Births a Trend in Brazil

AFP (Apr. 24, 2015) — More than half of Brazil&apos;s babies are born via cesarean section, as mothers and doctors opt for a faster and less painful experience despite the health risks. Duration: 02:02 Video provided by AFP
Powered by NewsLook.com
Anti-Malaria Jab Hope

Anti-Malaria Jab Hope

Reuters - News Video Online (Apr. 24, 2015) — The world&apos;s first anti-malaria vaccine could get the go-ahead for use in Africa from October if approved by international regulators. Paul Chapman reports. Video provided by Reuters
Powered by NewsLook.com
3D Food Printing: The Meal of the Future?

3D Food Printing: The Meal of the Future?

AP (Apr. 23, 2015) — Developers of 3D food printing hope the culinary technology will revolutionize the way we cook and eat. (April 23) Video provided by AP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:

Strange & Offbeat Stories

 

Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins