Featured Research

from universities, journals, and other organizations

Obese Women With Early-stage Breast Cancer More Likely To Die Than Women Of Normal Weight

Date:
October 7, 2004
Source:
Fox Chase Cancer Center
Summary:
Women who are obese when they are diagnosed with early-stage breast cancer are at a greater risk of dying of their disease than women of normal weight. That is the result of a study conducted by researchers at the Fox Chase Cancer Center in Philadelphia.

Women who are obese when they are diagnosed with early-stage breast cancer are at a greater risk of dying of their disease than women of normal weight. That is the result of a study conducted by researchers at the Fox Chase Cancer Center in Philadelphia, Pa. and presented today at the 46th Annual Meeting of the American Society for Therapeutic Radiology and Oncology in Atlanta, Ga.

The study compared the outcome data of obese, overweight and normal-weight women with early-stage breast cancer treated with conservation surgery (lumpectomy) and radiation therapy.

"We have demonstrated a significant association between obesity and adverse breast cancer outcome in patients with early-stage breast cancer," explained Penny Anderson, M.D., a radiation oncologist at Fox Chase and lead investigator of the study. "Despite being diagnosed with early stage disease, which is more commonly cured, obese women more often developed metastatic disease and more often died."

The influence of obesity on breast cancer outcome has been uncertain, especially in early-stage breast cancer patients. Previous studies show that obesity is a risk factor for the development of breast cancer, but these prior studies have reported contradictory results regarding the influence of obesity on outcome in breast cancer patients.

For this study, researchers analyzed the data of 2,010 patients from 1978 to 2003 with stage I/II breast cancer who were treated with lumpectomy, lymph-node dissection and radiation therapy with or without chemotherapy. Patients were categorized into three groups according to their weight: normal (452 patients) overweight (857 patients) and obese (701).

"Our results show a statistically significant difference between obese women and the other groups," said Anderson.

The five-year rates for overall survival were 92 percent, 92 percent and 88 percent for the normal-weight, overweight and obese groups, respectively. Five-year rates of distant metastasis were 7 percent for women of normal weight, 6 percent for overweight women and 10 percent for the obese group.

"Because the prevalence of obesity increases with age, as does the risk of breast cancer, interventions that enhance weight control may have a substantial effect on breast cancer outcome," Anderson said.

###

Fox Chase Cancer Center was founded in 1904 in Philadelphia as the nation's first cancer hospital. In 1974, Fox Chase became one of the first institutions designated as a National Cancer Institute Comprehensive Cancer Center. Fox Chase conducts basic, clinical, population and translational research; programs of prevention, detection and treatment of cancer; and community outreach. For more information about Fox Chase activities, visit the Center's web site at http://www.fccc.edu or call 1-888-FOX CHASE.


Story Source:

The above story is based on materials provided by Fox Chase Cancer Center. Note: Materials may be edited for content and length.


Cite This Page:

Fox Chase Cancer Center. "Obese Women With Early-stage Breast Cancer More Likely To Die Than Women Of Normal Weight." ScienceDaily. ScienceDaily, 7 October 2004. <www.sciencedaily.com/releases/2004/10/041007085945.htm>.
Fox Chase Cancer Center. (2004, October 7). Obese Women With Early-stage Breast Cancer More Likely To Die Than Women Of Normal Weight. ScienceDaily. Retrieved September 16, 2014 from www.sciencedaily.com/releases/2004/10/041007085945.htm
Fox Chase Cancer Center. "Obese Women With Early-stage Breast Cancer More Likely To Die Than Women Of Normal Weight." ScienceDaily. www.sciencedaily.com/releases/2004/10/041007085945.htm (accessed September 16, 2014).

Share This



More Health & Medicine News

Tuesday, September 16, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

President To Send 3,000 Military Personnel To Fight Ebola

President To Send 3,000 Military Personnel To Fight Ebola

Newsy (Sep. 16, 2014) President Obama is expected to send 3,000 troops to West Africa as part of the effort to contain Ebola's spread. Video provided by Newsy
Powered by NewsLook.com
Man Floats for 31 Hours in Gulf Waters

Man Floats for 31 Hours in Gulf Waters

AP (Sep. 16, 2014) A Texas man is lucky to be alive after he and three others floated for more than a day in the Gulf of Mexico when their boat sank during a fishing trip. (Sept. 16) Video provided by AP
Powered by NewsLook.com
EU Ministers and Experts Meet to Discuss Ebola Reponse

EU Ministers and Experts Meet to Discuss Ebola Reponse

AFP (Sep. 15, 2014) The European Commission met on Monday to coordinate aid that the EU can offer to African countries affected by the Ebola outbreak. Duration: 00:58 Video provided by AFP
Powered by NewsLook.com
Despite The Risks, Antibiotics Still Overprescribed For Kids

Despite The Risks, Antibiotics Still Overprescribed For Kids

Newsy (Sep. 15, 2014) A new study finds children are prescribed antibiotics twice as often as is necessary. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

    Environment News

      Technology News



      Save/Print:
      Share:

      Free Subscriptions


      Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

      Get Social & Mobile


      Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

      Have Feedback?


      Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
      Mobile: iPhone Android Web
      Follow: Facebook Twitter Google+
      Subscribe: RSS Feeds Email Newsletters
      Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins