Featured Research

from universities, journals, and other organizations

Annual Vaccination Against Influenza Associated With Decreased Risk Of Death In Elderly

Date:
November 10, 2004
Source:
Journal Of The American Medical Association
Summary:
A study from the Netherlands suggests that elderly persons who receive a yearly influenza vaccination have reduced risk of death from all causes, according to a study in the November 3 issue of JAMA.

A study from the Netherlands suggests that elderly persons who receive a yearly influenza vaccination have reduced risk of death from all causes, according to a study in the November 3 issue of JAMA.

"Influenza-associated morbidity and mortality increase with age, especially for individuals with high-risk conditions," the authors provide as background information in the article. "The effectiveness of vaccination has been reported to decrease in high-risk persons. Annual influenza revaccination has been proposed as a strategy to increase vaccination effectiveness."

In this study, A.C.G. Voordouw, M.D., from Erasmus Medical Center, Rotterdam, The Netherlands, and colleagues, analyzed data from 1996 through 2002 from electronic patient records that were part of the Integrated Primary Care Information Project of Medical Informatics at the Erasmus Medical Center. The study included 26,071 persons aged 65 years or older. During the total study period, the population studied received 62,476 influenza vaccinations. The annual vaccination coverage ranged from 64 percent in 1996 to 74 percent in 1999. Influenza epidemics during the study period were of mild to moderate severity with the 2000 – 2001 season showing no clear epidemic activity.

During the study followup period, 3,485 patients died. "Overall, a first vaccination was associated with a nonsignificant annual reduction of mortality (death) risk of 10 percent, while revaccination was associated with a reduced mortality risk of 24 percent," the authors report. "Compared with a first vaccination, revaccination was associated with a reduced annual mortality risk of 15 percent. During the epidemic periods this reduction was 28 percent." The authors also found that an interruption of the annual vaccinations series was associated with a 25 percent increase in mortality risk, whereas restarting vaccination after an interruption resulted in a mortality risk reduction similar to that observed following revaccination. The authors note that "in the total population one death was prevented for every 302 vaccinations, or 1 for every 195 revaccinations."

"In summary, our study shows that annual revaccination against influenza in a population of community-dwelling elderly persons is associated with a reduction of mortality risk. This study supports the recommendation for yearly influenza vaccination for elderly individuals, not only for those with comorbid illness but also in those without comorbidity and in patients 80 years or older. Because influenza vaccination is inexpensive and safe, clinicians should recommend annual influenza revaccination for such patients."

###

(JAMA. 2004;292:2089-2095. Available post-embargo at JAMA.com)

Editor's Note: This study was supported by an unconditional grant from the Netherlands Organisation for Health Research and Development. The grant was obtained following review of a submitted protocol to evaluate the effectiveness of the influenza vaccination program in Dutch elderly citizens. [Co-author] Dr. D. J. Smith was supported by a European Union grant.


Story Source:

The above story is based on materials provided by Journal Of The American Medical Association. Note: Materials may be edited for content and length.


Cite This Page:

Journal Of The American Medical Association. "Annual Vaccination Against Influenza Associated With Decreased Risk Of Death In Elderly." ScienceDaily. ScienceDaily, 10 November 2004. <www.sciencedaily.com/releases/2004/11/041104003056.htm>.
Journal Of The American Medical Association. (2004, November 10). Annual Vaccination Against Influenza Associated With Decreased Risk Of Death In Elderly. ScienceDaily. Retrieved October 22, 2014 from www.sciencedaily.com/releases/2004/11/041104003056.htm
Journal Of The American Medical Association. "Annual Vaccination Against Influenza Associated With Decreased Risk Of Death In Elderly." ScienceDaily. www.sciencedaily.com/releases/2004/11/041104003056.htm (accessed October 22, 2014).

Share This



More Health & Medicine News

Wednesday, October 22, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

CDC Revamps Ebola Guidelines After Criticism

CDC Revamps Ebola Guidelines After Criticism

Newsy (Oct. 21, 2014) The Centers for Disease Control and Prevention have issued new protocols for healthcare workers interacting with Ebola patients. Video provided by Newsy
Powered by NewsLook.com
WHO: Ebola Vaccine Trials to Start a in January

WHO: Ebola Vaccine Trials to Start a in January

AP (Oct. 21, 2014) Tens of thousands of doses of experimental Ebola vaccines could be available for "real-world" testing in West Africa as soon as January as long as they are deemed safe in soon to start trials, the World Health Organization said Tuesday. (Oct. 21) Video provided by AP
Powered by NewsLook.com
First-Of-Its-Kind Treatment Gives Man Ability To Walk Again

First-Of-Its-Kind Treatment Gives Man Ability To Walk Again

Newsy (Oct. 21, 2014) A medical team has for the first time given a man the ability to walk again after transplanting cells from his brain onto his severed spinal cord. Video provided by Newsy
Powered by NewsLook.com
CDC Issues New Ebola Guidelines for Health Workers

CDC Issues New Ebola Guidelines for Health Workers

Reuters - US Online Video (Oct. 21, 2014) The U.S. Centers for Disease Control and Prevention has set up new guidelines for health workers taking care of patients infected with Ebola. Linda So reports. Video provided by Reuters
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins