Featured Research

from universities, journals, and other organizations

Exercise Training In Ordinary People Affects The Activity Of 500 Genes

Date:
May 2, 2005
Source:
Karolinska Institutet
Summary:
A new study from Karolinska Institutet in Stockholm shows that hundreds of genes in the thigh muscle are activated in regular cycle training. The study also reveals that great differences in training response may be due to the ability in some people to activate their genes much more forcefully.

A new study from Karolinska Institutet in Stockholm shows that hundreds of genes in the thigh muscle are activated in regular cycle training. The study also reveals that great differences in training response may be due to the ability in some people to activate their genes much more forcefully. The study is published May 2 in FASEB Journal.

Related Articles


It is common knowledge that it is very dangerous to be inactive and that regular physical activity brings health, improves quality of life and extends life span. How these positive effects are created in the body is not known. Influences on gene activity in the heart, vessels and muscles are probably immensely important.

In this study, the first of its kind, Drs James Timmons, Carl J Sundberg and co-workers show that hundreds of genes are activated by regular cycle training for six weeks in young healthy men. Some of these genes are most likely linked to diabetes and cardiovascular disease. These training study findings can therefore be important for the development of new treatment strategies for such diseases.


Some people respond more easily to training than others. It is not known what explains this. The results from the training study show that those individuals that improved their performance most also activated several genes in the muscles markedly more. This has not been shown before.

Finally, the researchers made a comparison between the effects of endurance training and the situation in patients with Duchenne’s muscle dystrophy, a muscle wasting disease. Most of the muscle genes previously claimed to be specific for Duchenne were also activated with endurance training. Maybe the musculature in Duchenne patients strive to adapt in part similar to what happens in training. The results from this study will help to clarify which genes are uniquely affected in Duchenne.

Story Source:

The above story is based on materials provided by Karolinska Institutet. Note: Materials may be edited for content and length.


Cite This Page:

Karolinska Institutet. "Exercise Training In Ordinary People Affects The Activity Of 500 Genes." ScienceDaily. ScienceDaily, 2 May 2005. <www.sciencedaily.com/releases/2005/05/050502190527.htm>.
Karolinska Institutet. (2005, May 2). Exercise Training In Ordinary People Affects The Activity Of 500 Genes. ScienceDaily. Retrieved March 6, 2015 from www.sciencedaily.com/releases/2005/05/050502190527.htm
Karolinska Institutet. "Exercise Training In Ordinary People Affects The Activity Of 500 Genes." ScienceDaily. www.sciencedaily.com/releases/2005/05/050502190527.htm (accessed March 6, 2015).

Share This


More From ScienceDaily



More Health & Medicine News

Friday, March 6, 2015

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Just A Half-Hour Of Lost Sleep Could Lead To Weight Gain

Just A Half-Hour Of Lost Sleep Could Lead To Weight Gain

Newsy (Mar. 6, 2015) A new study found losing just half an hour of sleep could make you gain weight. Video provided by Newsy
Powered by NewsLook.com
Suicide Rates Up For Young Women In U.S.

Suicide Rates Up For Young Women In U.S.

Newsy (Mar. 6, 2015) According to a report from the CDC, suicide rates among young women increased from 1994 to 2012 while rates among young men have decreased. Video provided by Newsy
Powered by NewsLook.com
Bupa Eyes India Healthcare Opportunities

Bupa Eyes India Healthcare Opportunities

Reuters - Business Video Online (Mar. 5, 2015) Bupa is hoping to expand in India&apos;s fast-growing health insurance market, once a rule change on foreign investment is implemented. The British private healthcare group&apos;s CEO tells Grace Pascoe why it&apos;s so keen on the new opportunity. Video provided by Reuters
Powered by NewsLook.com
Liberia Releases Last Ebola Patient, But Threat Remains

Liberia Releases Last Ebola Patient, But Threat Remains

Newsy (Mar. 5, 2015) Liberia&apos;s last Ebola patient has been released, and the country hasn&apos;t recorded a new case in a week. However, fears of another outbreak still exist. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins