A new study from Karolinska Institutet in Stockholm shows that hundreds of genes in the thigh muscle are activated in regular cycle training. The study also reveals that great differences in training response may be due to the ability in some people to activate their genes much more forcefully. The study is published May 2 in FASEB Journal.
It is common knowledge that it is very dangerous to be inactive and that regular physical activity brings health, improves quality of life and extends life span. How these positive effects are created in the body is not known. Influences on gene activity in the heart, vessels and muscles are probably immensely important.
In this study, the first of its kind, Drs James Timmons, Carl J Sundberg and co-workers show that hundreds of genes are activated by regular cycle training for six weeks in young healthy men. Some of these genes are most likely linked to diabetes and cardiovascular disease. These training study findings can therefore be important for the development of new treatment strategies for such diseases.
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