Featured Research

from universities, journals, and other organizations

U Of MN Researchers Discover Novel Way Estrogen Affects The Brain

Date:
May 21, 2005
Source:
University of Minnesota
Summary:
University of Minnesota researchers have demonstrated for the first time how estrogen affects learning and memory. They found that estrogen can activate particular glutamate receptors within the hippocampus, the brain region responsible for many aspects of learning and memory.

University of Minnesota researchers have demonstrated how estrogen affects learning and memory. They found that estrogen can activate particular glutamate receptors within the hippocampus, the brain region responsible for many aspects of learning and memory. Glutamate is the primary excitatory neurotransmitter in the brain, allowing for fast communication between neurons. By examining hippocampal neurons from rats, researchers also observed that estrogen only activated the processes related to learning and memory in the brains of female rats and not males. While it has been well documented that estrogen influences other behaviors beyond reproduction, including learning and memory, the mechanism has remained elusive. The findings of this research are in this week's Journal of Neuroscience.

"We believe this is an important first step in understanding not just how estrogen affects learning and memory, but also a variety of non-reproductive behaviors," says Paul Mermelstein, Ph.D., assistant professor of neuroscience at the University of Minnesota and lead researcher. "Estrogen activation of glutamate receptors within other brain regions could also potentially account for the well-documented actions of this hormone on female motor control and pain sensation."

Marissa Boulware, a University of Minnesota neuroscience graduate student who performed the studies states, "Every day post-menopausal women face the dilemma of taking estrogens to improve their cognitive abilities, knowing it may pose a potential heath risk. By better understanding how estrogen acts upon our brain, one day we may develop novel therapies using non-steroidal drugs to mimic the specific actions of estrogen on processes related to learning and memory, affording the cognitive benefits of estrogen without any detrimental side effects."

The research was funded by the National Institutes of Health.


Story Source:

The above story is based on materials provided by University of Minnesota. Note: Materials may be edited for content and length.


Cite This Page:

University of Minnesota. "U Of MN Researchers Discover Novel Way Estrogen Affects The Brain." ScienceDaily. ScienceDaily, 21 May 2005. <www.sciencedaily.com/releases/2005/05/050521124436.htm>.
University of Minnesota. (2005, May 21). U Of MN Researchers Discover Novel Way Estrogen Affects The Brain. ScienceDaily. Retrieved September 2, 2014 from www.sciencedaily.com/releases/2005/05/050521124436.htm
University of Minnesota. "U Of MN Researchers Discover Novel Way Estrogen Affects The Brain." ScienceDaily. www.sciencedaily.com/releases/2005/05/050521124436.htm (accessed September 2, 2014).

Share This




More Health & Medicine News

Tuesday, September 2, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Snack Attack: Study Says Action Movies Make You Snack More

Snack Attack: Study Says Action Movies Make You Snack More

Newsy (Sep. 2, 2014) You're more likely to gain weight while watching action flicks than you are watching other types of programming, says a new study published in JAMA. Video provided by Newsy
Powered by NewsLook.com
U.N. Says Ebola Travel Restrictions Will Cause Food Shortage

U.N. Says Ebola Travel Restrictions Will Cause Food Shortage

Newsy (Sep. 2, 2014) The U.N. says the problem is two-fold — quarantine zones and travel restrictions are limiting the movement of both people and food. Video provided by Newsy
Powered by NewsLook.com
Doctors Fear They're Losing Battle Against Ebola

Doctors Fear They're Losing Battle Against Ebola

AP (Sep. 2, 2014) As a third American missionary is confirmed to have contracted Ebola in Liberia, doctors on the ground in West Africa fear they're losing the battle against the outbreak. (Sept. 2) Video provided by AP
Powered by NewsLook.com
Tech Giants Bet on 3D Headsets for Gaming, Healthcare

Tech Giants Bet on 3D Headsets for Gaming, Healthcare

AFP (Sep. 2, 2014) When Facebook acquired the virtual reality hardware developer Oculus VR in March for $2 billion, CEO Mark Zuckerberg hailed the firm's technology as "a new communication platform." Duration: 02:24 Video provided by AFP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins