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Gene Therapy To Treat Haemophilia; Cure Achieved In Dogs -- Are Humans Next?

Date:
August 12, 2005
Source:
Research Australia
Summary:
A leading researcher from Philadelphia USA, Professor Katherine High, is examining the obstacles to successful gene therapy in human patients with haemophilia.

Progress in gene therapy to treat haemophilia has been impressive inthe past few years. Gene therapy has been used to successfully treathaemophilia in dogs. A leading researcher from Philadelphia USA,Professor Katherine High, is examining the obstacles to successful genetherapy in human patients with haemophilia. She hopes that the problemsmay be overcome in the next five years to develop a successful genetransfer approach for sufferers of haemophilia.

"It has taken approximately 5 to 8 years to move from a cure forhaemophilia in mice to a cure in dogs. This has been achieved bymultiple gene transfer strategies. Clinical studies have identifiedwhich aspects of gene transfer therapy in dogs are directly applicablein humans and have identified potential problems, such as mode ofdelivery, which must be overcome before applying this approach inhumans," said High.

Professor High will review these exciting findings and thesteps to achieving a successful outcome in humans at the XXth Congressof the International Society on Thrombosis & Haemostasis in Sydneytoday.


Story Source:

The above story is based on materials provided by Research Australia. Note: Materials may be edited for content and length.


Cite This Page:

Research Australia. "Gene Therapy To Treat Haemophilia; Cure Achieved In Dogs -- Are Humans Next?." ScienceDaily. ScienceDaily, 12 August 2005. <www.sciencedaily.com/releases/2005/08/050811104518.htm>.
Research Australia. (2005, August 12). Gene Therapy To Treat Haemophilia; Cure Achieved In Dogs -- Are Humans Next?. ScienceDaily. Retrieved September 16, 2014 from www.sciencedaily.com/releases/2005/08/050811104518.htm
Research Australia. "Gene Therapy To Treat Haemophilia; Cure Achieved In Dogs -- Are Humans Next?." ScienceDaily. www.sciencedaily.com/releases/2005/08/050811104518.htm (accessed September 16, 2014).

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