Featured Research

from universities, journals, and other organizations

Oral Contraceptives Associated With Reduced Risk Of Multiple Sclerosis

Date:
September 29, 2005
Source:
JAMA and Archives Journals
Summary:
Over a three-year period, the risk of developing multiple sclerosis (MS) was reduced in women taking oral contraceptives, according to a study in the September issue of Archives of Neurology, one of the JAMA/Archives journals.

CHICAGO – Over a three-year period, the risk of developing multiple sclerosis (MS) was reduced in women taking oral contraceptives, according to a study in the September issue of Archives of Neurology, one of the JAMA/Archives journals.

In previous studies, estrogen delayed the onset and eased the course of a MS-like disease in animals, suggesting that oral contraceptives, which contain estrogen, and pregnancy and the postpartum period afterward, both states associated with profound hormonal changes, may alter the clinical course or affect the risk of developing the disease, according to background information in the article.

Αlvaro Alonso, M.D., Ph.D., of the Harvard School of Public Health, Boston, and colleagues compared 106 women who had a new diagnosis of MS between January 1, 1993 and December 31, 2000 with 1,001 matched women without MS as controls. Individuals included in the analysis were drawn from a research database that includes medical and pharmacy records for three million Britons.

"The incidence of MS in OC [oral contraceptives] users was 40 percent lower than in nonusers," the authors report. "Women had a higher risk of developing first symptoms of MS in the six months following a pregnancy and a non-significant lower risk during pregnancy, compared with those with no pregnancy. … This is consistent with studies on the effect of pregnancy in patients with MS and the immunological changes associated with pregnancy."

"Recent OC use and, possibly, current pregnancy are associated with a lower risk of developing MS," the authors conclude. "On the contrary, the postpartum period confers a higher risk of MS onset. Our findings suggest that high levels of exogenous [from outside the body] estrogens from OC use and of endogenous [from the body] estrogens during pregnancy may delay the first clinical attack of MS."

###

(Arch Neurol. 2005; 62:1362-1365. Available pre-embargo to the media at www.jamamedia.org.)

Editor's Note: This study was supported by a grant from the National Multiple Sclerosis Society, New York, N.Y. Dr. Alonso was supported by a Fulbright Program fellowship, New York.


Story Source:

The above story is based on materials provided by JAMA and Archives Journals. Note: Materials may be edited for content and length.


Cite This Page:

JAMA and Archives Journals. "Oral Contraceptives Associated With Reduced Risk Of Multiple Sclerosis." ScienceDaily. ScienceDaily, 29 September 2005. <www.sciencedaily.com/releases/2005/09/050929202016.htm>.
JAMA and Archives Journals. (2005, September 29). Oral Contraceptives Associated With Reduced Risk Of Multiple Sclerosis. ScienceDaily. Retrieved April 24, 2014 from www.sciencedaily.com/releases/2005/09/050929202016.htm
JAMA and Archives Journals. "Oral Contraceptives Associated With Reduced Risk Of Multiple Sclerosis." ScienceDaily. www.sciencedaily.com/releases/2005/09/050929202016.htm (accessed April 24, 2014).

Share This



More Health & Medicine News

Thursday, April 24, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Big Pharma Braces for M&A Wave

Big Pharma Braces for M&A Wave

Reuters - Business Video Online (Apr. 22, 2014) — Big pharma on the move as Novartis boss, Joe Jimenez, tells Reuters about plans to transform his company via an asset exchange with GSK, and Astra Zeneca shares surge on speculation that Pfizer is looking for a takeover. Joanna Partridge reports. Video provided by Reuters
Powered by NewsLook.com
Study Says Most Crime Not Linked To Mental Illness

Study Says Most Crime Not Linked To Mental Illness

Newsy (Apr. 22, 2014) — A new study finds most crimes committed by people with mental illness are not caused by symptoms of their illness or disorder. Video provided by Newsy
Powered by NewsLook.com
Hagel Gets Preview of New High-Tech Projects

Hagel Gets Preview of New High-Tech Projects

AP (Apr. 22, 2014) — Defense Secretary Chuck Hagel is given hands-on demonstrations Tuesday of some of the newest research from DARPA _ the military's Defense Advanced Research Projects Agency program. (April 22) Video provided by AP
Powered by NewsLook.com
How Smaller Plates And Cutlery Could Make You Feel Fuller

How Smaller Plates And Cutlery Could Make You Feel Fuller

Newsy (Apr. 22, 2014) — NBC's "Today" conducted an experiment to see if changing the size of plates and utensils affects the amount individuals eat. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins