Featured Research

from universities, journals, and other organizations

Oral Contraceptives Associated With Reduced Risk Of Multiple Sclerosis

Date:
September 29, 2005
Source:
JAMA and Archives Journals
Summary:
Over a three-year period, the risk of developing multiple sclerosis (MS) was reduced in women taking oral contraceptives, according to a study in the September issue of Archives of Neurology, one of the JAMA/Archives journals.

CHICAGO – Over a three-year period, the risk of developingmultiple sclerosis (MS) was reduced in women taking oralcontraceptives, according to a study in the September issue of Archivesof Neurology, one of the JAMA/Archives journals.

In previousstudies, estrogen delayed the onset and eased the course of a MS-likedisease in animals, suggesting that oral contraceptives, which containestrogen, and pregnancy and the postpartum period afterward, bothstates associated with profound hormonal changes, may alter theclinical course or affect the risk of developing the disease, accordingto background information in the article.

Αlvaro Alonso, M.D.,Ph.D., of the Harvard School of Public Health, Boston, and colleaguescompared 106 women who had a new diagnosis of MS between January 1,1993 and December 31, 2000 with 1,001 matched women without MS ascontrols. Individuals included in the analysis were drawn from aresearch database that includes medical and pharmacy records for threemillion Britons.

"The incidence of MS in OC [oral contraceptives]users was 40 percent lower than in nonusers," the authors report."Women had a higher risk of developing first symptoms of MS in the sixmonths following a pregnancy and a non-significant lower risk duringpregnancy, compared with those with no pregnancy. … This is consistentwith studies on the effect of pregnancy in patients with MS and theimmunological changes associated with pregnancy."

"Recent OC useand, possibly, current pregnancy are associated with a lower risk ofdeveloping MS," the authors conclude. "On the contrary, the postpartumperiod confers a higher risk of MS onset. Our findings suggest thathigh levels of exogenous [from outside the body] estrogens from OC useand of endogenous [from the body] estrogens during pregnancy may delaythe first clinical attack of MS."

###

(Arch Neurol. 2005; 62:1362-1365. Available pre-embargo to the media at www.jamamedia.org.)

Editor'sNote: This study was supported by a grant from the National MultipleSclerosis Society, New York, N.Y. Dr. Alonso was supported by aFulbright Program fellowship, New York.


Story Source:

The above story is based on materials provided by JAMA and Archives Journals. Note: Materials may be edited for content and length.


Cite This Page:

JAMA and Archives Journals. "Oral Contraceptives Associated With Reduced Risk Of Multiple Sclerosis." ScienceDaily. ScienceDaily, 29 September 2005. <www.sciencedaily.com/releases/2005/09/050929202016.htm>.
JAMA and Archives Journals. (2005, September 29). Oral Contraceptives Associated With Reduced Risk Of Multiple Sclerosis. ScienceDaily. Retrieved September 17, 2014 from www.sciencedaily.com/releases/2005/09/050929202016.htm
JAMA and Archives Journals. "Oral Contraceptives Associated With Reduced Risk Of Multiple Sclerosis." ScienceDaily. www.sciencedaily.com/releases/2005/09/050929202016.htm (accessed September 17, 2014).

Share This



More Health & Medicine News

Wednesday, September 17, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

President To Send 3,000 Military Personnel To Fight Ebola

President To Send 3,000 Military Personnel To Fight Ebola

Newsy (Sep. 16, 2014) — President Obama is expected to send 3,000 troops to West Africa as part of the effort to contain Ebola's spread. Video provided by Newsy
Powered by NewsLook.com
Obama Orders Military Response to Ebola

Obama Orders Military Response to Ebola

AP (Sep. 16, 2014) — Calling the Ebola outbreak in West Africa a potential threat to global security, President Barack Obama is ordering 3,000 U.S. military personnel to the stricken region amid worries that the outbreak is spiraling out of control. (Sept. 16) Video provided by AP
Powered by NewsLook.com
UN: 20,000 Could Be Infected With Ebola by Year End

UN: 20,000 Could Be Infected With Ebola by Year End

AFP (Sep. 16, 2014) — Nearly $1.0 billion dollars is needed to fight the Ebola outbreak raging in west Africa, the United Nations say, warning that 20,000 could be infected by year end. Duration: 00:40 Video provided by AFP
Powered by NewsLook.com
Obama: Ebola Outbreak Threat to Global Security

Obama: Ebola Outbreak Threat to Global Security

AP (Sep. 16, 2014) — President Obama is ordering U.S. military personnel to West Africa to deal with the Ebola outbreak, which is he calls a potential threat to global security. (Sept. 16) Video provided by AP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

    Environment News

      Technology News



      Save/Print:
      Share:  

      Free Subscriptions


      Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

      Get Social & Mobile


      Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

      Have Feedback?


      Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
      Mobile iPhone Android Web
      Follow Facebook Twitter Google+
      Subscribe RSS Feeds Email Newsletters
      Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins