Featured Research

from universities, journals, and other organizations

Cool Therapy Reduces Brain Injury And Death From Oxygen Loss In Newborns

Date:
October 13, 2005
Source:
Yale University
Summary:
Infants born with oxygen loss who are given an innovative therapy that lowers their entire body temperature by four degrees within the first six hours of life, have a better chance of survival and lower incidence of brain injury, according to a report in the October 13 issue of the New England Journal of Medicine.

Infants born with oxygen loss who are given an innovative therapy thatlowers their entire body temperature by four degrees within the firstsix hours of life, have a better chance of survival and lower incidenceof brain injury, according to a report in the October 13 issue of theNew England Journal of Medicine.

"We speculate that this therapy lowers the brain temperature as well asbody temperature and slows down the injury process caused by birthasphyxia, which results in loss of oxygen to the brain," said Yaleresearcher Richard A. Ehrenkranz, M.D., professor of pediatricneonatology and obstetrics and gynecology at Yale School of Medicineand Yale-New Haven Hospital. "Less injury means a better outcome andfewer cases of cerebral palsy and other complications."

Ehrenkranz co-authored the study with colleagues at 14 otherinstitutions in the National Institute of Child Health and HumanDevelopment Neonatal Research Network.

Hypoxic ischemic encephalopathy (HIE) occurs when an infant's brainfails to receive sufficient oxygen or blood before birth. The conditionmay occur hours before birth or during labor and delivery. It can becaused by complications such as compression or tearing of the placentaor the umbilical cord and rupture of the uterus. Many infants whosurvive HIE experience brain disability.

The team, led by Seetha Shankaran, M.D., at Wayne State Universitystudied the effect of hypothermia or reduced body temperature, infull-term infants with asphyxia and related complications at birth.Researchers randomly assigned 208 infants to either a control group ora whole-body cooling group where their body temperature was kept at92.3 degrees for 72 hours, then slowly re-warmed. Body temperatureswere lowered by placing babies on a blanket initially filled withcirculating 41-degree water. Both groups received standard newbornintensive care including monitoring of vital signs.

When the infants were examined to assess their outcome at 18 to 22months of age, 44 percent of those in the group treated withhypothermia developed a moderate to severe disability or had died, ascompared to 62 percent in the control group.

The Neonatal Research Network will also follow both groups of childrenuntil they reach age six or seven, to compare the incidence of healthproblems or learning difficulties.

###

Citation: New England Journal of Medicine 353; 15 (October 13, 2005)


Story Source:

The above story is based on materials provided by Yale University. Note: Materials may be edited for content and length.


Cite This Page:

Yale University. "Cool Therapy Reduces Brain Injury And Death From Oxygen Loss In Newborns." ScienceDaily. ScienceDaily, 13 October 2005. <www.sciencedaily.com/releases/2005/10/051013081625.htm>.
Yale University. (2005, October 13). Cool Therapy Reduces Brain Injury And Death From Oxygen Loss In Newborns. ScienceDaily. Retrieved September 22, 2014 from www.sciencedaily.com/releases/2005/10/051013081625.htm
Yale University. "Cool Therapy Reduces Brain Injury And Death From Oxygen Loss In Newborns." ScienceDaily. www.sciencedaily.com/releases/2005/10/051013081625.htm (accessed September 22, 2014).

Share This



More Health & Medicine News

Monday, September 22, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Sierra Leone in Lockdown to Control Ebola

Sierra Leone in Lockdown to Control Ebola

AP (Sep. 21, 2014) Sierra Leone residents remained in lockdown on Saturday as part of a massive effort to confine millions of people to their homes in a bid to stem the biggest Ebola outbreak in history. (Sept. 20) Video provided by AP
Powered by NewsLook.com
Sierra Leone's Nationwide Ebola Curfew Underway

Sierra Leone's Nationwide Ebola Curfew Underway

Newsy (Sep. 20, 2014) Sierra Leone is locked down as aid workers and volunteers look for new cases of Ebola. Video provided by Newsy
Powered by NewsLook.com
Changes Found In Brain After One Dose Of Antidepressants

Changes Found In Brain After One Dose Of Antidepressants

Newsy (Sep. 19, 2014) A study suggest antidepressants can kick in much sooner than previously thought. Video provided by Newsy
Powered by NewsLook.com
Could Grief Affect The Immune Systems Of Senior Citizens?

Could Grief Affect The Immune Systems Of Senior Citizens?

Newsy (Sep. 19, 2014) The study found elderly people are much more likely to become susceptible to infection than younger adults going though a similar situation. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins