Featured Research

from universities, journals, and other organizations

Fentanyl Patch Safe And Effective Alternative To Oral Opioids For Pediatric Pain Patients

Date:
November 14, 2005
Source:
John Wiley & Sons, Inc.
Summary:
A new study says using a transdermal patch to deliver the opioid fentanyl is an effective way to control pain in children. Results indicate that the fentanyl patch is safe for children aged 2 to 16 years.

A new study says using a transdermal patch to deliver the opioid fentanyl is an effective way to control pain in children. Results from an international study published in the December 15, 2005 issue of CANCER (http://www.interscience.wiley.com/cancer-newsroom), a peer-reviewed journal of the American Cancer Society, indicate that the fentanyl patch is safe for children aged 2 to 16 years.

Opioids, such as morphine and its derivatives, have been shown to clearly reduce pain and improve quality of life in adults. However, little is known about the pain experience and the safety and efficacy of this class of analgesics in children. Until recently, children were thought to feel pain to a lesser degree and have a higher risk of addiction than adults. Newer information indicates that not only do children experience severe pain and are no more at risk for addiction than adults, but they are also at greater risk for psychological disturbances that have immediate and long-term developmental impact. However, children may not readily accept the methods of delivery of most opioids -- that is, injection or pill.

Julia C. Finkel, M.D. of the Children's National Medical Center in Washington, D.C. and international colleagues examined 173 children from ages 2 to 16 years, many of whom were cancer patients and who had a history of chronic severe pain and prior oral opioid use. They were transitioned to the fentanyl patch adjusted to equal the concentration of previous oral doses and followed for 15 days.

The researchers found that subjective pain and quality of life improved significantly. By Day 16 the average daily pain intensity score decreased. Many patients elected to continue in the study for three months. After one month, quality of life scores improved. At the end of three months, average play performance scores also showed significant improvement. There were no more adverse experiences than reported in adults and no adverse experiences specific for the pediatric population.

The authors write: "Results from global measurements of pain treatment, safety and quality of life indicate that transdermal fentanyl is an acceptable alternative to oral opioid therapy in children." An opioid patch, such as fentanyl, "is especially useful for good pain management in children with life-threatening conditions in which oral or injectable routes of drug delivery are difficult to administer or add further distress."

###

Article: "Transdermal Fentanyl in the Management of Children with Chronic Severe Pain: Results from an International Study," Julia C. Finkel, Allen Finley, Christine Greco, Steve J. Weisman, Lonnie Zeltzer, CANCER; Published Online: November 14, 2005 (DOI: 10.1002/cncr.21497); Print Issue Date: December 15, 2005.


Story Source:

The above story is based on materials provided by John Wiley & Sons, Inc.. Note: Materials may be edited for content and length.


Cite This Page:

John Wiley & Sons, Inc.. "Fentanyl Patch Safe And Effective Alternative To Oral Opioids For Pediatric Pain Patients." ScienceDaily. ScienceDaily, 14 November 2005. <www.sciencedaily.com/releases/2005/11/051114215750.htm>.
John Wiley & Sons, Inc.. (2005, November 14). Fentanyl Patch Safe And Effective Alternative To Oral Opioids For Pediatric Pain Patients. ScienceDaily. Retrieved October 23, 2014 from www.sciencedaily.com/releases/2005/11/051114215750.htm
John Wiley & Sons, Inc.. "Fentanyl Patch Safe And Effective Alternative To Oral Opioids For Pediatric Pain Patients." ScienceDaily. www.sciencedaily.com/releases/2005/11/051114215750.htm (accessed October 23, 2014).

Share This



More Health & Medicine News

Thursday, October 23, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Orthodontist Mom Jennifer Salzer on the Best Time for Braces

Orthodontist Mom Jennifer Salzer on the Best Time for Braces

Working Mother (Oct. 22, 2014) Is your child ready? Video provided by Working Mother
Powered by NewsLook.com
U.S. Issues Ebola Travel Restrictions, Are Visa Bans Next?

U.S. Issues Ebola Travel Restrictions, Are Visa Bans Next?

Newsy (Oct. 22, 2014) Now that the U.S. is restricting travel from West Africa, some are dropping questions about a travel ban and instead asking about visa bans. Video provided by Newsy
Powered by NewsLook.com
US to Track Everyone Coming from Ebola Nations

US to Track Everyone Coming from Ebola Nations

AP (Oct. 22, 2014) Stepping up their vigilance against Ebola, federal authorities said Wednesday that everyone traveling into the US from Ebola-stricken nations will be monitored for symptoms for 21 days. (Oct. 22) Video provided by AP
Powered by NewsLook.com
Doctors Help Paralysed Man Walk Again, Patient in Disbelief

Doctors Help Paralysed Man Walk Again, Patient in Disbelief

AFP (Oct. 22, 2014) Polish doctors describe how they helped a paralysed man walk again, with the patient in disbelief at the return of sensation to his legs. Duration: 1:04 Video provided by AFP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins