Featured Research

from universities, journals, and other organizations

Jefferson Researchers Find Drug May Give Some Cardiac Protection 24 Hours After Heart Attack

Date:
November 20, 2005
Source:
Thomas Jefferson University Hospital
Summary:
A drug has been shown to provide some protection to the heart from injury even if given as much as 24 hours after a heart attack, Jefferson Medical College researchers report. Darbepoietin, a long-acting cousin of erythropoietin (EPO), offered significant protection to heart tissue from injury from ischemia, and even helped improve cardiac function.

A drug has been shown to provide some protection to the heart from injury even if given as much as 24 hours after a heart attack, Jefferson Medical College researchers report.

Walter Koch, Ph.D., director of the Center for Translational Medicine in the Department of Medicine at Jefferson Medical College of Thomas Jefferson University in Philadelphia, and his co-workers knew that the drug Darbepoietin alpha would protect the ischemic heart. Darbepoietin is a long-acting cousin of erythropoietin (EPO), which has been shown to offer some protection to the heart from injury from ischemia, or a lack of oxygen. In previous studies, Dr. Koch had given EPO at the time of simulated heart attack in an another animal model, and found it protected the animals.

But in further studies, Dr. Koch gave Darbepoietin to animals at the time of ischemia and heart attack, one to two hours after, and 24 hours later. In each case, the scientists saw that the drug offered significant protection to heart tissue, and even helped improve cardiac function.

Dr. Koch believes the results “may be quickly translated into clinical trials.” He and his team present their findings on November 16, 2005 at the American Heart Association’s Scientific Sessions 2005 in Dallas.


Story Source:

The above story is based on materials provided by Thomas Jefferson University Hospital. Note: Materials may be edited for content and length.


Cite This Page:

Thomas Jefferson University Hospital. "Jefferson Researchers Find Drug May Give Some Cardiac Protection 24 Hours After Heart Attack." ScienceDaily. ScienceDaily, 20 November 2005. <www.sciencedaily.com/releases/2005/11/051120121557.htm>.
Thomas Jefferson University Hospital. (2005, November 20). Jefferson Researchers Find Drug May Give Some Cardiac Protection 24 Hours After Heart Attack. ScienceDaily. Retrieved August 21, 2014 from www.sciencedaily.com/releases/2005/11/051120121557.htm
Thomas Jefferson University Hospital. "Jefferson Researchers Find Drug May Give Some Cardiac Protection 24 Hours After Heart Attack." ScienceDaily. www.sciencedaily.com/releases/2005/11/051120121557.htm (accessed August 21, 2014).

Share This




More Health & Medicine News

Thursday, August 21, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Drug Used To Treat 'Ebola's Cousin' Shows Promise

Drug Used To Treat 'Ebola's Cousin' Shows Promise

Newsy (Aug. 21, 2014) An experimental drug used to treat Marburg virus in rhesus monkeys could give new insight into a similar treatment for Ebola. Video provided by Newsy
Powered by NewsLook.com
Cadavers, a Teen, and a Medical School Dream

Cadavers, a Teen, and a Medical School Dream

AP (Aug. 21, 2014) Contains graphic content. He's only 17. But Johntrell Bowles has wanted to be a doctor from a young age, despite the odds against him. He was recently the youngest participant in a cadaver program at the Indiana University NW medical school. (Aug. 21) Video provided by AP
Powered by NewsLook.com
American Ebola Patients Released: What Cured Them?

American Ebola Patients Released: What Cured Them?

Newsy (Aug. 21, 2014) It's unclear whether the American Ebola patients' recoveries can be attributed to an experimental drug or early detection and good medical care. Video provided by Newsy
Powered by NewsLook.com
Lost Brain Cells To Blame For Sleep Problems Among Seniors

Lost Brain Cells To Blame For Sleep Problems Among Seniors

Newsy (Aug. 21, 2014) According to a new study, elderly people might have trouble sleeping because of the loss of a certain group of neurons in the brain. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins