Featured Research

from universities, journals, and other organizations

Scientists Explore How Complex Organs Develop From A Simple Bud

Date:
September 8, 2006
Source:
Blackwell Publishing Ltd.
Summary:
The current issue of Differentiation, guest-edited by Brigid Hogan, highlights several scientific investigations into the complex biological mechanism known as branching morphogenesis. Through a series of seven laboratory reviews, important insights governing this process during animal development are revealed. The articles analyze how branching morphogenesis occurs in different organ systems in the same species. They also compare the process between simple and complex organisms.

The current issue of Differentiation, guest-edited by Brigid Hogan, highlights several scientific investigations into the complex biological mechanism known as branching morphogenesis. Through a series of seven laboratory reviews, important insights governing this process during animal development are revealed. The articles analyze how branching morphogenesis occurs in different organ systems in the same species. They also compare the process between simple and complex organisms.

Related Articles


Key questions within the reviews --pertaining to the maintenance and repair of cells within adult branched organs, the role of cells only transiently associated with adult organs, and the extent to which defects in the growth and development of fetal stage organs can affect organ function after birth -- have important implications for human health.

Two of the reviews in the Journal delve into tubulogenesis – a process that is intimately tied to branching morphogenesis. Another contains research aimed at helping patients whose salivary glands have been injured by radiation therapy or autoimmune rejection. An investigation into the morphogenesis of the prostate gland and seminal vesicles is included, as well as an in-depth look at the genetic and cellular interactions critical to placental development. Research on this process in mouse kidneys generated a real-time tracking procedure which has significant implications for genetic manipulation.

Ultimately, scientists hope analysis of branching morphogenesis will lead to the design of a computer program that is able to virtually reconstruct the complete process of organogenesis –from simple bud to complex organ. The reviews in this special issue of Differentiation are written by top scientists offering fresh ideas and pertinent background information to readers interested in anything from molecular to cellular and developmental biology.

Differentiation is a multidisciplinary journal dealing with all problems relating to cell differentiation, development, cellular structure and function, and cancer. Differentiation of eukaryotes at the molecular level and the use of transgenic and targeted mutagenesis approaches to problems of differentiation are of particular interest to the journal. It publishes full-length articles containing original work in any of these areas, as well as reviews on topics of current interest in the field.


Story Source:

The above story is based on materials provided by Blackwell Publishing Ltd.. Note: Materials may be edited for content and length.


Cite This Page:

Blackwell Publishing Ltd.. "Scientists Explore How Complex Organs Develop From A Simple Bud." ScienceDaily. ScienceDaily, 8 September 2006. <www.sciencedaily.com/releases/2006/09/060908000804.htm>.
Blackwell Publishing Ltd.. (2006, September 8). Scientists Explore How Complex Organs Develop From A Simple Bud. ScienceDaily. Retrieved November 29, 2014 from www.sciencedaily.com/releases/2006/09/060908000804.htm
Blackwell Publishing Ltd.. "Scientists Explore How Complex Organs Develop From A Simple Bud." ScienceDaily. www.sciencedaily.com/releases/2006/09/060908000804.htm (accessed November 29, 2014).

Share This


More From ScienceDaily



More Plants & Animals News

Saturday, November 29, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Research on Bats Could Help Develop Drugs Against Ebola

Research on Bats Could Help Develop Drugs Against Ebola

AFP (Nov. 28, 2014) In Africa's only biosafety level 4 laboratory, scientists have been carrying out experiments on bats to understand how virus like Ebola are being transmitted, and how some of them resist to it. Duration: 01:18 Video provided by AFP
Powered by NewsLook.com
New Dinosaur Species Found in Museum Collection

New Dinosaur Species Found in Museum Collection

Reuters - Innovations Video Online (Nov. 27, 2014) A British palaeontologist has discovered a new species of dinosaur while studying fossils in a Canadian museum. Pentaceratops aquilonius was related to Triceratops and lived at the end of the Cretaceous Period, around 75 million years ago. Jim Drury has more. Video provided by Reuters
Powered by NewsLook.com
Tryptophan Isn't Making You Sleepy On Thanksgiving

Tryptophan Isn't Making You Sleepy On Thanksgiving

Newsy (Nov. 27, 2014) Tryptophan, a chemical found naturally in turkey meat, gets blamed for sleepiness after Thanksgiving meals. But science points to other culprits. Video provided by Newsy
Powered by NewsLook.com
Classic Hollywood Memorabilia Goes Under the Hammer

Classic Hollywood Memorabilia Goes Under the Hammer

Reuters - Entertainment Video Online (Nov. 26, 2014) The iconic piano from "Casablanca" and the Cowardly Lion suit from "The Wizard of Oz" fetch millions at auction. Sara Hemrajani reports. Video provided by Reuters
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Plants & Animals

Earth & Climate

Fossils & Ruins

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins