Featured Research

from universities, journals, and other organizations

Ghost Authorship Of Industry Funded Drug Trials Is Common

Date:
January 16, 2007
Source:
Public Library of Science
Summary:
Ghost authorship is the failure to name, as an author, an individual who has made a substantial contribution to a scientific article. A study of 44 industry-initiated trials from Denmark in the 1990s found evidence of ghost authorship for 33 trials, which increased to 40 if a person qualifying for authorship was just acknowledged rather than being named as an author.

Ghost authorship is the failure to name, as an author, an individual who has made a substantial contribution to a scientific article. A study of 44 industry-initiated trials from Denmark in the 1990s found evidence of ghost authorship for 33 trials, which increased to 40 if a person qualifying for authorship was just acknowledged rather than being named as an author.

The researchers, led by Peter C. Gřtzsche from the Nordic Cochrane Centre, Copenhagen, Denmark, studied all published industry-initiated randomised trials approved in 1994--1995 by the Scientific-Ethical Committees for Copenhagen and Frederiksberg in Denmark. They compared the full trial protocols (which were written before the trial was begun) approved by these ethical committees with the primary scientific report which resulted from these trials, and which was published in a peer-reviewed journal.

Ghost authorship was defined as present if individuals who wrote the trial protocol, performed the statistical analyses, or wrote the manuscript, were not listed as authors of the publication, or as members of a study group or writing committee, or in an acknowledgment. Of the 44 trials included, 43 were initiated by one of 26 multinational pharmaceutical firms and one by a local company.

In 31 trials, the ghost authors identified were statisticians. Eight publications acknowledged the assistance of statisticians, and four acknowledged the assistance of medical writers. Conversely, although all published reports had clinicians as authors no trial protocol or publication stated explicitly that the study report or the manuscript was to be written or was written by the clinical investigators, and none of the protocols stated that clinical investigators were to be involved with data analysis. It was also unclear whether clinicians had contributed to the protocols.

This study is the first that has systematically examined the prevalence of ghost authorship using a cohort of protocols and corresponding publications. The authors conclude that "ghost authorship in industry-initiated randomised trials is very common, and we believe that this practice serves commercial purposes". They go on to urge that in order to reduce the prevalence of ghost authorship existing guidelines, such as those drawn up by the International Committee on Medical Journal Editors, World Association of Medical Editors and European Medical Writers Association are followed. This action could increase the chance that publications accurately, fairly, and comprehensively reflect the data collected from trials

A related perspective by Liz Wager, an independent editorial consultant, who has been involved in drawing up guidelines for medical writers, discusses the implication of these findings further.

Citation: Gřtzsche PC, Hróbjartsson A, Johansen HK, Haahr MT, Altman DG, et al. (2007) Ghost authorship in industry-initiated randomised trials. PLoS Med 4(1): e19. (http://dx.doi.org/10.1371/journal.pmed.0040019)


Story Source:

The above story is based on materials provided by Public Library of Science. Note: Materials may be edited for content and length.


Cite This Page:

Public Library of Science. "Ghost Authorship Of Industry Funded Drug Trials Is Common." ScienceDaily. ScienceDaily, 16 January 2007. <www.sciencedaily.com/releases/2007/01/070115215757.htm>.
Public Library of Science. (2007, January 16). Ghost Authorship Of Industry Funded Drug Trials Is Common. ScienceDaily. Retrieved July 31, 2014 from www.sciencedaily.com/releases/2007/01/070115215757.htm
Public Library of Science. "Ghost Authorship Of Industry Funded Drug Trials Is Common." ScienceDaily. www.sciencedaily.com/releases/2007/01/070115215757.htm (accessed July 31, 2014).

Share This




More Health & Medicine News

Thursday, July 31, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

House Republicans Vote to Sue Obama Over Healthcare Law

House Republicans Vote to Sue Obama Over Healthcare Law

Reuters - US Online Video (July 31, 2014) — The Republican-led House of Representatives votes to sue President Obama, accusing him of overstepping his executive authority in making changes to the Affordable Care Act. Mana Rabiee reports. Video provided by Reuters
Powered by NewsLook.com
Despite Health Questions, E-Cigs Are Beneficial: Study

Despite Health Questions, E-Cigs Are Beneficial: Study

Newsy (July 31, 2014) — Citing 81 previous studies, new research out of London suggests the benefits of smoking e-cigarettes instead of regular ones outweighs the risks. Video provided by Newsy
Powered by NewsLook.com
Dangerous Bacteria Kills One in Florida

Dangerous Bacteria Kills One in Florida

AP (July 31, 2014) — Sarasota County, Florida health officials have issued a warning against eating raw oysters and exposing open wounds to coastal and inland waters after a dangerous bacteria killed one person and made another sick. (July 31) Video provided by AP
Powered by NewsLook.com
Health Insurers' Profits Slide

Health Insurers' Profits Slide

Reuters - Business Video Online (July 30, 2014) — Obamacare-related costs were said to be behind the profit plunge at Wellpoint and Humana, but Wellpoint sees the new exchanges boosting its earnings for the full year. Fred Katayama reports. Video provided by Reuters
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



    Save/Print:
    Share:  

    Free Subscriptions


    Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

    Get Social & Mobile


    Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

    Have Feedback?


    Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
    Mobile iPhone Android Web
    Follow Facebook Twitter Google+
    Subscribe RSS Feeds Email Newsletters
    Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins