Featured Research

from universities, journals, and other organizations

Stem Cells May Help Heal Joint Injuries

Date:
February 6, 2007
Source:
University of Guelph
Summary:
As anyone who's ever injured a knee or elbow will tell you, recovery can be a long and painful process. Cartilage is an exceptionally slow-healing tissue, and, until now, the missing or damaged tissue is often irreplaceable. Researchers at the University of Guelph are hoping stem cells might provide the needed tissue replacements.

As anyone who’s ever injured a knee or elbow will tell you, recovery can be a long and painful process. Cartilage is an exceptionally slow-healing tissue, and, until now, the missing or damaged tissue is often irreplaceable. Researchers at the University of Guelph are hoping stem cells might provide the needed tissue replacements.

Related Articles


Biomedical sciences professor Dean Betts and doctoral candidate Thomas Koch are hoping to use stem cells to improve cartilage healing after joint injuries. They’re working with horses, where joint injuries are both common and costly, and say the research could be a model for helping human joint injuries.

“Equine joints are similar to human joints in aspects such as joint thickness and spontaneous athletic injuries, so the research may be transferable,” said Koch.

Much of the team’s research focuses on perfecting the technique for isolating, expanding and differentiating adult stem cells. They’re using blood from the umbilical cord of horses as a source of stem cells. Because most horses are observed when foaling, it’s relatively easy to collect the cord blood at that time.

Obtaining cord blood samples is non-invasive and much easier than obtaining stem cells from an embryo. Koch said there’s evidence that stem cells from cord blood are “younger” than bone marrow stem cells, which means they’re capable of more divisions, and creating more diverse tissue types. The younger stem cells may also be less prone to rejection when used to help heal cartilage in another body.

Because there are no other reports on isolating stem cells from equine cord blood, Betts and Koch are eager to gather as much information as possible. Already, they’ve succeeded in differentiating the cord blood stem cells into three different cell types including chondrocytes – the building blocks of cartilage.

Betts said the three-dimensional structure of cartilage and its attachment to the underlying bone is difficult to reproduce. Despite this, there have been encouraging results using osteochondral grafts – pieces of bone and cartilage grafted to the site of the injury. He hopes further research will reveal more ways to reconstruct the tissue either at the injury site, or as a graft that can be surgically implanted.


Story Source:

The above story is based on materials provided by University of Guelph. Note: Materials may be edited for content and length.


Cite This Page:

University of Guelph. "Stem Cells May Help Heal Joint Injuries." ScienceDaily. ScienceDaily, 6 February 2007. <www.sciencedaily.com/releases/2007/02/070205193746.htm>.
University of Guelph. (2007, February 6). Stem Cells May Help Heal Joint Injuries. ScienceDaily. Retrieved November 25, 2014 from www.sciencedaily.com/releases/2007/02/070205193746.htm
University of Guelph. "Stem Cells May Help Heal Joint Injuries." ScienceDaily. www.sciencedaily.com/releases/2007/02/070205193746.htm (accessed November 25, 2014).

Share This


More From ScienceDaily



More Health & Medicine News

Tuesday, November 25, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

From Popcorn To Vending Snacks: FDA Ups Calorie Count Rules

From Popcorn To Vending Snacks: FDA Ups Calorie Count Rules

Newsy (Nov. 25, 2014) The US FDA is announcing new calorie rules on Tuesday that will require everywhere from theaters to vending machines to include calorie counts. Video provided by Newsy
Powered by NewsLook.com
Daily Serving Of Yogurt Could Reduce Risk Of Type 2 Diabetes

Daily Serving Of Yogurt Could Reduce Risk Of Type 2 Diabetes

Newsy (Nov. 25, 2014) Need another reason to eat yogurt every day? Researchers now say it could reduce a person's risk of developing type 2 diabetes. Video provided by Newsy
Powered by NewsLook.com
Madagascar Working to Contain Plague Outbreak

Madagascar Working to Contain Plague Outbreak

AFP (Nov. 24, 2014) Madagascar said Monday it is trying to contain an outbreak of plague -- similar to the Black Death that swept Medieval Europe -- that has killed 40 people and is spreading to the capital Antananarivo. Duration: 00:42 Video provided by AFP
Powered by NewsLook.com
Are Female Bosses More Likely To Be Depressed?

Are Female Bosses More Likely To Be Depressed?

Newsy (Nov. 24, 2014) A new study links greater authority with increased depressive symptoms among women in the workplace. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins