Featured Research

from universities, journals, and other organizations

Severely Mentally Ill Have Increased Risk Of Death From Cardiovascular Disease

Date:
February 7, 2007
Source:
JAMA and Archives Journals
Summary:
A large British study indicates that individuals with severe mental illnesses are significantly more likely to die from coronary heart disease and stroke, but not cancer, than those without mental illnesses, according to a report in the February issue of Archives of General Psychiatry, one of the JAMA/Archives journals.

A large British study indicates that individuals with severe mental illnesses are significantly more likely to die from coronary heart disease and stroke, but not cancer, than those without mental illnesses, according to a report in the February issue of Archives of General Psychiatry, one of the JAMA/Archives journals.

Physical health is a concern among those with severe mental illnesses, according to background information in the article. The adverse effects of antipsychotic medication, along with smoking, lifestyle factors and poverty, may contribute to physical illness in this population. However, estimates for rates of cancer and heart disease among the mentally ill have been conflicting.

David P.J. Osborn, Ph.D., and colleagues at the Royal Free and University College Medical School, London, selected 46,136 individuals with severe mental illness (including schizophrenia, schizoaffective disorder, bipolar disorder and delusional disorder) and 300,426 without mental illness from a nationally representative database in the United Kingdom. The researchers compared the two group's death rates from coronary heart disease, stroke and the seven most common types of cancer in the United Kingdom--respiratory, colorectal, breast, prostate, stomach, esophageal and pancreatic cancer. "We chose to study death rates rather than incidence rates, because mortality is the most robust outcome since it includes diagnoses made post-mortem," the authors write.

Over a follow-up period of at least six months, individuals of all ages were significantly more likely to die from coronary heart disease and stroke if they had a severe mental illness. Those with severe mental illness age 18 to 49 were 3.22 times as likely to die from heart disease and 2.53 times as likely to die from stroke; those age 50 to 75 were 1.86 times more likely to die from heart disease and 1.89 times more likely to die from stroke, and those older than 75 were 1.05 times as likely to die from heart disease and 1.34 times as likely to die from stroke.

The rates did not change significantly after the researchers adjusted for smoking rates and social deprivation, both of which contribute to the risk for heart disease. The use of antipsychotic medication, however, did have an effect. "People with severe mental illness who were not prescribed any antipsychotics were at increased risk of coronary heart disease and stroke than controls, whereas those prescribed such agents were at even greater risk," the authors write. "Those receiving the higher doses were at greatest risk for death from both coronary heart disease and stroke."

"With the exception of respiratory tumors, people with severe mental illness were not at increased risk of dying from the seven most common cancers in the United Kingdom," they continue. "However, our data did not confirm other evidence that they were protected from cancers."

Additional research is needed to help prevent cardiovascular disease and death among those with severe mental illness, the authors conclude. "Clinically, a holistic approach to the care of people with severe mental illness is still frequently overlooked," they write. "Such an approach requires monitoring for somatic conditions and demands effective communication between primary and secondary care to provide coherent physical health care."


Story Source:

The above story is based on materials provided by JAMA and Archives Journals. Note: Materials may be edited for content and length.


Cite This Page:

JAMA and Archives Journals. "Severely Mentally Ill Have Increased Risk Of Death From Cardiovascular Disease." ScienceDaily. ScienceDaily, 7 February 2007. <www.sciencedaily.com/releases/2007/02/070206095736.htm>.
JAMA and Archives Journals. (2007, February 7). Severely Mentally Ill Have Increased Risk Of Death From Cardiovascular Disease. ScienceDaily. Retrieved July 25, 2014 from www.sciencedaily.com/releases/2007/02/070206095736.htm
JAMA and Archives Journals. "Severely Mentally Ill Have Increased Risk Of Death From Cardiovascular Disease." ScienceDaily. www.sciencedaily.com/releases/2007/02/070206095736.htm (accessed July 25, 2014).

Share This




More Health & Medicine News

Friday, July 25, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Beatings and Addiction: Pakistan Drug 'clinic' Tortures Patients

Beatings and Addiction: Pakistan Drug 'clinic' Tortures Patients

AFP (July 24, 2014) A so-called drugs rehab 'clinic' is closed down in Pakistan after police find scores of ‘patients’ chained up alleging serial abuse. Duration 03:05 Video provided by AFP
Powered by NewsLook.com
Too Few Teens Receiving HPV Vaccination, CDC Says

Too Few Teens Receiving HPV Vaccination, CDC Says

Newsy (July 24, 2014) The Centers for Disease Control and Prevention is blaming doctors for the low number of children being vaccinated for HPV. Video provided by Newsy
Powered by NewsLook.com
New Painkiller Designed To Discourage Abuse: Will It Work?

New Painkiller Designed To Discourage Abuse: Will It Work?

Newsy (July 24, 2014) The FDA approved Targiniq ER on Wednesday, a painkiller designed to keep users from abusing it. Like any new medication, however, it has doubters. Video provided by Newsy
Powered by NewsLook.com
Doctor At Forefront Of Fighting Ebola Outbreak Gets Ebola

Doctor At Forefront Of Fighting Ebola Outbreak Gets Ebola

Newsy (July 24, 2014) Sheik Umar Khan has treated many of the people infected in the Ebola outbreak, and now he's become one of them. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

    Health News

      Environment News

        Technology News



          Save/Print:
          Share:

          Free Subscriptions


          Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

          Get Social & Mobile


          Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

          Have Feedback?


          Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
          Mobile: iPhone Android Web
          Follow: Facebook Twitter Google+
          Subscribe: RSS Feeds Email Newsletters
          Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins