Featured Research

from universities, journals, and other organizations

Hormone Therapy May Be Safer With Patch Than Pill

Date:
February 21, 2007
Source:
American Heart Association
Summary:
Transdermal estrogen, delivered by a patch or gel, is not associated with an increased risk of blood clots in veins, according to French researchers reporting in Circulation: Journal of the American Heart Association. The blood clots, called venous thromboembolism (VTE), are only a risk when taking estrogen by mouth.

Transdermal estrogen, delivered by a patch or gel, is not associated with an increased risk of blood clots in veins, according to French researchers reporting in Circulation: Journal of the American Heart Association. The blood clots, called venous thromboembolism (VTE), are only a risk when taking estrogen by mouth.

Data from this multicenter case-control study of VTE among postmenopausal women also suggest that micronised progesterone and pregnane derivatives (medroxyprogesterone acetate) appear safe with respect to thrombotic risk. However, norpregnane derivatives cause clots.

The researchers looked at data on 271 women with first-ever VTE, and compared them to 610 women without VTE. The women in the EStrogen and THromboEmbolism Risk (ESTHER) study, which involved women 45 to 70 years old and was conducted between 1999 and 2005 in France.

Compared with women not taking estrogen replacement, those who used oral estrogen had a 4.2 times higher risk of VTE, while women using transdermal estrogen had 0.9 times the risk. The researchers found no significant association of VTE with micronised progesterone and pregnane derivatives. By contrast, norpregnane derivatives were associated with a 4-fold-increased VTE risk.

"If confirmed," said the authors, "these findings could benefit women in the management of their menopausal symptoms."


Story Source:

The above story is based on materials provided by American Heart Association. Note: Materials may be edited for content and length.


Cite This Page:

American Heart Association. "Hormone Therapy May Be Safer With Patch Than Pill." ScienceDaily. ScienceDaily, 21 February 2007. <www.sciencedaily.com/releases/2007/02/070220014706.htm>.
American Heart Association. (2007, February 21). Hormone Therapy May Be Safer With Patch Than Pill. ScienceDaily. Retrieved September 18, 2014 from www.sciencedaily.com/releases/2007/02/070220014706.htm
American Heart Association. "Hormone Therapy May Be Safer With Patch Than Pill." ScienceDaily. www.sciencedaily.com/releases/2007/02/070220014706.htm (accessed September 18, 2014).

Share This



More Health & Medicine News

Thursday, September 18, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

The Cost of Ebola

The Cost of Ebola

Reuters - Business Video Online (Sep. 18, 2014) As Sierra Leone prepares for a three-day "lockdown" in its latest bid to stem the spread of Ebola, Ciara Lee looks at the financial implications of fighting the largest ever outbreak of the disease. Video provided by Reuters
Powered by NewsLook.com
What HealthKit Bug Means For Your iOS Fitness Apps

What HealthKit Bug Means For Your iOS Fitness Apps

Newsy (Sep. 18, 2014) Apple has delayed the launch of the HealthKit app platform, citing a bug. Video provided by Newsy
Powered by NewsLook.com
Residents Vaccinated as Haiti Fights Cholera Epidemic

Residents Vaccinated as Haiti Fights Cholera Epidemic

AFP (Sep. 18, 2014) Haitians receive the second dose of the vaccine against cholera as part of the UN's vaccination campaign. Duration: 00:34 Video provided by AFP
Powered by NewsLook.com
Artificial Sweetener Could Promote Diabetes

Artificial Sweetener Could Promote Diabetes

Newsy (Sep. 17, 2014) Doctors once thought artificial sweeteners lacked the health risks of sugar, but a new study says they can impact blood sugar levels the same way. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins