Featured Research

from universities, journals, and other organizations

Hormone Therapy May Be Safer With Patch Than Pill

Date:
February 21, 2007
Source:
American Heart Association
Summary:
Transdermal estrogen, delivered by a patch or gel, is not associated with an increased risk of blood clots in veins, according to French researchers reporting in Circulation: Journal of the American Heart Association. The blood clots, called venous thromboembolism (VTE), are only a risk when taking estrogen by mouth.

Transdermal estrogen, delivered by a patch or gel, is not associated with an increased risk of blood clots in veins, according to French researchers reporting in Circulation: Journal of the American Heart Association. The blood clots, called venous thromboembolism (VTE), are only a risk when taking estrogen by mouth.

Data from this multicenter case-control study of VTE among postmenopausal women also suggest that micronised progesterone and pregnane derivatives (medroxyprogesterone acetate) appear safe with respect to thrombotic risk. However, norpregnane derivatives cause clots.

The researchers looked at data on 271 women with first-ever VTE, and compared them to 610 women without VTE. The women in the EStrogen and THromboEmbolism Risk (ESTHER) study, which involved women 45 to 70 years old and was conducted between 1999 and 2005 in France.

Compared with women not taking estrogen replacement, those who used oral estrogen had a 4.2 times higher risk of VTE, while women using transdermal estrogen had 0.9 times the risk. The researchers found no significant association of VTE with micronised progesterone and pregnane derivatives. By contrast, norpregnane derivatives were associated with a 4-fold-increased VTE risk.

"If confirmed," said the authors, "these findings could benefit women in the management of their menopausal symptoms."


Story Source:

The above story is based on materials provided by American Heart Association. Note: Materials may be edited for content and length.


Cite This Page:

American Heart Association. "Hormone Therapy May Be Safer With Patch Than Pill." ScienceDaily. ScienceDaily, 21 February 2007. <www.sciencedaily.com/releases/2007/02/070220014706.htm>.
American Heart Association. (2007, February 21). Hormone Therapy May Be Safer With Patch Than Pill. ScienceDaily. Retrieved July 24, 2014 from www.sciencedaily.com/releases/2007/02/070220014706.htm
American Heart Association. "Hormone Therapy May Be Safer With Patch Than Pill." ScienceDaily. www.sciencedaily.com/releases/2007/02/070220014706.htm (accessed July 24, 2014).

Share This




More Health & Medicine News

Thursday, July 24, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

New Painkiller Designed To Discourage Abuse: Will It Work?

New Painkiller Designed To Discourage Abuse: Will It Work?

Newsy (July 24, 2014) The FDA approved Targiniq ER on Wednesday, a painkiller designed to keep users from abusing it. Like any new medication, however, it has doubters. Video provided by Newsy
Powered by NewsLook.com
Doctor At Forefront Of Fighting Ebola Outbreak Gets Ebola

Doctor At Forefront Of Fighting Ebola Outbreak Gets Ebola

Newsy (July 24, 2014) Sheik Umar Khan has treated many of the people infected in the Ebola outbreak, and now he's become one of them. Video provided by Newsy
Powered by NewsLook.com
Condemned Man's US Execution Takes Nearly Two Hours

Condemned Man's US Execution Takes Nearly Two Hours

AFP (July 24, 2014) America's death penalty debate raged Thursday after it took nearly two hours for Arizona to execute a prisoner who lost a Supreme Court battle challenging the experimental lethal drug cocktail. Duration: 00:55 Video provided by AFP
Powered by NewsLook.com
China's Ageing Millions Look Forward to Bleak Future

China's Ageing Millions Look Forward to Bleak Future

AFP (July 24, 2014) China's elderly population is expanding so quickly that children struggle to look after them, pushing them to do something unexpected in Chinese society- move their parents into a nursing home. Duration: 02:07 Video provided by AFP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins