Featured Research

from universities, journals, and other organizations

Enzyme Finding Sheds Light On How Memories Are Made And What Goes Wrong In Brain Disorders

Date:
March 2, 2007
Source:
University of Bristol
Summary:
The function of an enzyme in the brain -- strongly linked to a number of major brain diseases such as Alzheimer's, schizophrenia and bipolar disorder -- has been identified for the first time by researchers at the University of Bristol, UK.

The function of an enzyme in the brain -- strongly linked to a number of major brain diseases such as Alzheimer's, schizophrenia and bi-polar disorder -- has been identified for the first time by researchers at the University of Bristol, UK.

These findings, published today in Neuron, will help in the understanding of how memories are laid down and what goes wrong in these disorders.

The research showed how controlling the activity of glycogen synthase kinase-3 (GSK3) might prevent a memory being erased by improving the strength of connections between neurons in the brain, thus allowing better consolidation of new information.

Professor Collingridge from the University of Bristol said: "While GSK3 has previously been implicated in major neurological disorders, until now its role in normal neuronal function has been largely unknown. Our new understanding will help pharmaceutical companies develop drugs to inhibit it when things go wrong."

Professor Graham Collingridge and his team, with colleagues from the University of British Columbia, revealed that the activity of GSK3 facilitates a form of 'cross-talk' between the two major forms of synaptic plasticity in the brain.

Synaptic plasticity is the strength of a connection between neurons and forms the basis of learning and memory.


Story Source:

The above story is based on materials provided by University of Bristol. Note: Materials may be edited for content and length.


Cite This Page:

University of Bristol. "Enzyme Finding Sheds Light On How Memories Are Made And What Goes Wrong In Brain Disorders." ScienceDaily. ScienceDaily, 2 March 2007. <www.sciencedaily.com/releases/2007/02/070228123316.htm>.
University of Bristol. (2007, March 2). Enzyme Finding Sheds Light On How Memories Are Made And What Goes Wrong In Brain Disorders. ScienceDaily. Retrieved October 2, 2014 from www.sciencedaily.com/releases/2007/02/070228123316.htm
University of Bristol. "Enzyme Finding Sheds Light On How Memories Are Made And What Goes Wrong In Brain Disorders." ScienceDaily. www.sciencedaily.com/releases/2007/02/070228123316.htm (accessed October 2, 2014).

Share This



More Mind & Brain News

Thursday, October 2, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Pregnancy Spacing Could Have Big Impact On Autism Risks

Pregnancy Spacing Could Have Big Impact On Autism Risks

Newsy (Oct. 1, 2014) A new study says children born less than one year and more than five years after a sibling can have an increased risk for autism. Video provided by Newsy
Powered by NewsLook.com
Stopping School Violence

Stopping School Violence

Ivanhoe (Oct. 1, 2014) A trauma doctor steps out of the hospital and into the classroom to teach kids how to calmly solve conflicts, avoiding a trip to the ER. Video provided by Ivanhoe
Powered by NewsLook.com
Pineal Cysts: Debilitating Pain

Pineal Cysts: Debilitating Pain

Ivanhoe (Oct. 1, 2014) A tiny cyst in the brain that can cause debilitating symptoms like chronic headaches and insomnia, and the doctor who performs the delicate surgery to remove them. Video provided by Ivanhoe
Powered by NewsLook.com
Burning Away Brain Tumors

Burning Away Brain Tumors

Ivanhoe (Oct. 1, 2014) Doctors are 'cooking' brain tumors. Hear how this new laser-heat procedure cuts down on recovery time. Video provided by Ivanhoe
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins