Featured Research

from universities, journals, and other organizations

Enzyme Finding Sheds Light On How Memories Are Made And What Goes Wrong In Brain Disorders

Date:
March 2, 2007
Source:
University of Bristol
Summary:
The function of an enzyme in the brain -- strongly linked to a number of major brain diseases such as Alzheimer's, schizophrenia and bipolar disorder -- has been identified for the first time by researchers at the University of Bristol, UK.

The function of an enzyme in the brain -- strongly linked to a number of major brain diseases such as Alzheimer's, schizophrenia and bi-polar disorder -- has been identified for the first time by researchers at the University of Bristol, UK.

Related Articles


These findings, published today in Neuron, will help in the understanding of how memories are laid down and what goes wrong in these disorders.

The research showed how controlling the activity of glycogen synthase kinase-3 (GSK3) might prevent a memory being erased by improving the strength of connections between neurons in the brain, thus allowing better consolidation of new information.

Professor Collingridge from the University of Bristol said: "While GSK3 has previously been implicated in major neurological disorders, until now its role in normal neuronal function has been largely unknown. Our new understanding will help pharmaceutical companies develop drugs to inhibit it when things go wrong."

Professor Graham Collingridge and his team, with colleagues from the University of British Columbia, revealed that the activity of GSK3 facilitates a form of 'cross-talk' between the two major forms of synaptic plasticity in the brain.

Synaptic plasticity is the strength of a connection between neurons and forms the basis of learning and memory.


Story Source:

The above story is based on materials provided by University of Bristol. Note: Materials may be edited for content and length.


Cite This Page:

University of Bristol. "Enzyme Finding Sheds Light On How Memories Are Made And What Goes Wrong In Brain Disorders." ScienceDaily. ScienceDaily, 2 March 2007. <www.sciencedaily.com/releases/2007/02/070228123316.htm>.
University of Bristol. (2007, March 2). Enzyme Finding Sheds Light On How Memories Are Made And What Goes Wrong In Brain Disorders. ScienceDaily. Retrieved April 21, 2015 from www.sciencedaily.com/releases/2007/02/070228123316.htm
University of Bristol. "Enzyme Finding Sheds Light On How Memories Are Made And What Goes Wrong In Brain Disorders." ScienceDaily. www.sciencedaily.com/releases/2007/02/070228123316.htm (accessed April 21, 2015).

Share This


More From ScienceDaily



More Mind & Brain News

Tuesday, April 21, 2015

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Research Says Complex Tools Might Not Be 'Our Thing' Anymore

Research Says Complex Tools Might Not Be 'Our Thing' Anymore

Newsy (Apr. 21, 2015) The use of complex tools has often been seen as a defining characteristic of humanity, but that notion is now in question. Video provided by Newsy
Powered by NewsLook.com
Our Love Of Puppy Dog Eyes Explained By Science

Our Love Of Puppy Dog Eyes Explained By Science

Newsy (Apr. 17, 2015) Researchers found a spike in oxytocin occurs in both humans and dogs when they gaze into each other&apos;s eyes. Video provided by Newsy
Powered by NewsLook.com
Scientists Find Link Between Gestational Diabetes And Autism

Scientists Find Link Between Gestational Diabetes And Autism

Newsy (Apr. 17, 2015) Researchers who analyzed data from over 300,000 kids and their mothers say they&apos;ve found a link between gestational diabetes and autism. Video provided by Newsy
Powered by NewsLook.com
Video Messages Help Reassure Dementia Patients

Video Messages Help Reassure Dementia Patients

AP (Apr. 17, 2015) Family members are prerecording messages as part of a unique pilot program at the Hebrew Home in New York. The videos are trying to help victims of Alzheimer&apos;s disease and other forms of dementia break through the morning fog of forgetfulness. (April 17) Video provided by AP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins