Featured Research

from universities, journals, and other organizations

Measles-mumps-rubella, Chicken Pox Vaccines Work For Preemies

Date:
March 7, 2007
Source:
University of Rochester Medical Center
Summary:
Vaccines for measles-mumps-rubella and varicella, or chicken pox, are effective in extremely preterm infants, even though preemies' immune systems are not as developed as full-term babies. This confirms a long-held assumption by pediatricians and neonatologists across the country.

Vaccines for measles-mumps-rubella and varicella, or chicken pox, are effective in extremely preterm infants, even though preemies' immune systems are not as developed as full-term babies. This confirms a long-held assumption by pediatricians and neonatologists across the country.

Related Articles


"The assumption has always been that it would be OK, that very early babies would have enough immunity, but no one had formally researched the subject," said Carl D'Angio, M.D., associate professor of Pediatrics at the University of Rochester Medical Center, and author of a paper on the subject in Pediatrics this month. "I'm happy be able to reassure my colleagues and parents that it is OK."

The study, which included 16 term and 16 extremely preterm (born before about 6 months of pregnancy) infants born between May 2002 and May 2005, is the first of its kind to examine the antibody levels of measles, mumps, rubella and varicella in this population before and after vaccination. It was published in this month's Pediatrics.

The same number of preterm infants and full-term infants in the study reached a level of immunity considered protective against the diseases. This positive outcome, however, was not guaranteed because preemies' immune systems do not always react the same way as full-term infants. For instance, a change in the types of vaccine used in the UK apparently resulted in an increase in Haemophilus influenzae type b infections, like bloodstream infection or meningitis, in children. Children born prematurely appeared to be particularly at risk for this, alluding to potential problems this population may have with responding to vaccines.

That isn't the case for the MMR and chicken pox vaccines. "Now we can all breathe a sigh of relief. We were right," D'Angio said.

Although not generally life-threatening, measles, mumps, rubella and chicken pox can all have serious complications. While many adults contracted chicken pox as a childhood rite of passage, the varicella virus killed 100 and hospitalized 11,000 people every year before the vaccine became available. Generally, the virus causes a rash, itching, fever and fatigue, but it can also cause severe skin infections, scars, pneumonia and brain damage. And a person who has had chicken pox can get a painful rash called shingles years later, according to the Centers for Disease Control and Prevention.

The measles virus causes a rash, cough, runny nose, eye irritation and fever, but it can also lead to ear infections, pneumonia, seizures, brain damage, and rarely, death. The mumps virus causes fever, headache and swollen glands, but it may also cause deafness, meningitis, painful swelling of the testicles or ovaries, and rarely, death. The rubella virus causes a rash, mild fever and arthritis, but in pregnant women, it can lead to a miscarriage or birth defects, according to the CDC.

D'Angio's study was funded by the National Institute of Allergy and Infectious Diseases and the National Center for Research Resources, both part of the National Institutes of Health. D'Angio is finishing a similar study on the pneumococcal conjugate vaccine, which helps prevent meningitis and blood and ear infections, and is in the process of studying the influenza vaccine.


Story Source:

The above story is based on materials provided by University of Rochester Medical Center. Note: Materials may be edited for content and length.


Cite This Page:

University of Rochester Medical Center. "Measles-mumps-rubella, Chicken Pox Vaccines Work For Preemies." ScienceDaily. ScienceDaily, 7 March 2007. <www.sciencedaily.com/releases/2007/03/070305092008.htm>.
University of Rochester Medical Center. (2007, March 7). Measles-mumps-rubella, Chicken Pox Vaccines Work For Preemies. ScienceDaily. Retrieved December 18, 2014 from www.sciencedaily.com/releases/2007/03/070305092008.htm
University of Rochester Medical Center. "Measles-mumps-rubella, Chicken Pox Vaccines Work For Preemies." ScienceDaily. www.sciencedaily.com/releases/2007/03/070305092008.htm (accessed December 18, 2014).

Share This


More From ScienceDaily



More Health & Medicine News

Thursday, December 18, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Kids Die While Under Protective Services

Kids Die While Under Protective Services

AP (Dec. 18, 2014) As part of a six-month investigation of child maltreatment deaths, the AP found that hundreds of deaths from horrific abuse and neglect could have been prevented. AP's Haven Daley reports. (Dec. 18) Video provided by AP
Powered by NewsLook.com
Dads-To-Be Also Experience Hormone Changes During Pregnancy

Dads-To-Be Also Experience Hormone Changes During Pregnancy

Newsy (Dec. 18, 2014) A study from University of Michigan researchers found that expectant fathers see a decrease in testosterone as the baby's birth draws near. Video provided by Newsy
Powered by NewsLook.com
Prenatal Exposure To Pollution Might Increase Autism Risk

Prenatal Exposure To Pollution Might Increase Autism Risk

Newsy (Dec. 18, 2014) Harvard researchers found children whose mothers were exposed to high pollution levels in the third trimester were twice as likely to develop autism. Video provided by Newsy
Powered by NewsLook.com
UN: Up to One Million Facing Hunger in Ebola-Hit Countries

UN: Up to One Million Facing Hunger in Ebola-Hit Countries

AFP (Dec. 17, 2014) Border closures, quarantines and crop losses in West African nations battling the Ebola virus could lead to as many as one million people going hungry, UN food agencies said on Wednesday. Duration: 00:52 Video provided by AFP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins