Featured Research

from universities, journals, and other organizations

Social Factors Not Genetics Drive Racial Disparities In Colorectal Cancer Survival, Study Says

Date:
April 23, 2007
Source:
John Wiley & Sons, Inc.
Summary:
Correcting social, economic and health-care inequalities may have the most significant impact in reducing survival differences in colorectal cancer between African-Americans and Caucasians, according to a new study.

Correcting social, economic and healthcare inequalities may have the most significant impact in reducing survival differences in colorectal cancer (CRC) between African Americans and Caucasians, according to a new study. Published in the June 1, 2007 issue of CANCER, a peer-reviewed journal of the American Cancer Society, a meta-analysis of data from published studies demonstrated that when socioeconomic factors and treatment utilization were controlled for or equalized, racial disparities were reduced substantially.

Lower socioeconomic status (SES) is well known to be associated with poorer health outcomes, including higher death rates. It is linked to impediments to healthcare access and receiving suboptimal care; higher risk of exposure to occupational and environmental hazards; and riskier behavior and less healthy lifestyles.

Survival differences in CRC between African Americans and whites have been well documented in the epidemiology literature. At the beginning of the 21st century, African Americans were dying from CRC at significant higher rates than white Americans. At five years after diagnosis, almost half of African Americans would be dead from CRC compared to just one third (35 percent) of white Americans. Research indicates that factors such as lower utilization of screening tests, lower rates of surgery and adjuvant chemotherapy, more aggressive tumors, and poor post-treatment surveillance contribute to lower survival rates. However, the fundamental causes of these associations, including the importance of biologic versus socioeconomic factors, remain poorly characterized.

For their new study, Dr. Xianglin Du, Tamra Meyer, and Dr. Luisa Franzini of the University Of Texas School Of Public Health at Houston reviewed the literature and aggregated the data from ten studies that investigated the association between CRC survival and race/ethnicity after controlling for SES and treatment. The meta-analysis approach aims to systematically review the existing literature, to allow a more objective appraisal of the evidence, to examine the heterogeneity between the studies, and if appropriate, to enhance the precision of the effect estimates.

The authors found that the overall risk of CRC-related death was only slightly elevated after adjusting for SES and treatment. African Americans had only marginally higher CRC mortality (hazard ratio: 1.13, 95 percent confidence interval: 1.01-1.28) and all-cause mortality (hazard ratio: 1.14, 95 percent confidence interval: 1.00-1.29).

"These findings," conclude the authors, "demonstrated that there is no strong evidence of racial disparities in survival between African-Americans and Caucasians with colon cancer after accounting for racial differences in socioeconomic status." Therefore, conclude the authors, "efforts to eliminate racial disparities in health care and to minimize disparities in socioeconomic status have the potential to reduce racial inequalities in colon cancer survival."

Article: "Meta-analysis of Racial Disparities in Survival in Association With Socioeconomic Status Among Men and Women with Colon Cancer," Xianglin L. Du, Tamra E. Meyer, Luisa Franzini, CANCER: Published Online: April 23, 2007

(DOI: 10.1002/cncr.22664); Print Issue Date: June 1, 2007.


Story Source:

The above story is based on materials provided by John Wiley & Sons, Inc.. Note: Materials may be edited for content and length.


Cite This Page:

John Wiley & Sons, Inc.. "Social Factors Not Genetics Drive Racial Disparities In Colorectal Cancer Survival, Study Says." ScienceDaily. ScienceDaily, 23 April 2007. <www.sciencedaily.com/releases/2007/04/070423080526.htm>.
John Wiley & Sons, Inc.. (2007, April 23). Social Factors Not Genetics Drive Racial Disparities In Colorectal Cancer Survival, Study Says. ScienceDaily. Retrieved October 21, 2014 from www.sciencedaily.com/releases/2007/04/070423080526.htm
John Wiley & Sons, Inc.. "Social Factors Not Genetics Drive Racial Disparities In Colorectal Cancer Survival, Study Says." ScienceDaily. www.sciencedaily.com/releases/2007/04/070423080526.htm (accessed October 21, 2014).

Share This



More Health & Medicine News

Tuesday, October 21, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

CDC Revamps Ebola Guidelines After Criticism

CDC Revamps Ebola Guidelines After Criticism

Newsy (Oct. 21, 2014) The Centers for Disease Control and Prevention have issued new protocols for healthcare workers interacting with Ebola patients. Video provided by Newsy
Powered by NewsLook.com
WHO: Ebola Vaccine Trials to Start a in January

WHO: Ebola Vaccine Trials to Start a in January

AP (Oct. 21, 2014) Tens of thousands of doses of experimental Ebola vaccines could be available for "real-world" testing in West Africa as soon as January as long as they are deemed safe in soon to start trials, the World Health Organization said Tuesday. (Oct. 21) Video provided by AP
Powered by NewsLook.com
First-Of-Its-Kind Treatment Gives Man Ability To Walk Again

First-Of-Its-Kind Treatment Gives Man Ability To Walk Again

Newsy (Oct. 21, 2014) A medical team has for the first time given a man the ability to walk again after transplanting cells from his brain onto his severed spinal cord. Video provided by Newsy
Powered by NewsLook.com
CDC Issues New Ebola Guidelines for Health Workers

CDC Issues New Ebola Guidelines for Health Workers

Reuters - US Online Video (Oct. 21, 2014) The U.S. Centers for Disease Control and Prevention has set up new guidelines for health workers taking care of patients infected with Ebola. Linda So reports. Video provided by Reuters
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins