Featured Research

from universities, journals, and other organizations

Children With Epilepsy Seizures May Benefit From New Animal Model Of Disease

Date:
April 26, 2007
Source:
American Academy of Neurology
Summary:
Researchers have developed an animal model of infantile spasms, improving the likelihood of finding new treatments for the thousands of young children who suffer from these catastrophic epilepsy seizures, according to new research.

Researchers have developed an animal model of infantile spasms, improving the likelihood of finding new treatments for the thousands of young children who suffer from these catastrophic epilepsy seizures, according to recent research.

Infantile spasms are a specific type of epilepsy seizure seen in infancy and early childhood. The disorder involves a sudden bending forward and stiffening of the body, arms, and legs. The seizures typically last one to five seconds and occur in clusters, ranging from two to 100 spasms at a time. There are few available treatments.

In two studies, the authors report developing a mouse model of infantile spasms that produces effects closely resembling human infantile spasms. The mouse model also responded to current treatments, including adrenocorticotrophic hormone (ACTH), in a similar manner.

"Infantile spasms can last for months to years in children. Having an animal model that resembles this long duration is likely to be useful for analyzing the evolution of this disease, and how it is best treated in different stages," said study author O. Carter Snead, III, MD, with the University of Toronto's Hospital for Sick Children in Toronto, Ontario, Canada, and Fellow of the American Academy of Neurology.

"Since children with this disorder often develop it without any apparent cause, such a mouse model will also improve the likelihood of finding new treatments," said study author Miguel Cortez, MD, with the University of Toronto's Hospital for Sick Children.

Both studies were supported by Bloorview Children's Hospital Foundation, the Canadian Institutes of Health Research, and the Hospital for Sick Children Foundation.


Story Source:

The above story is based on materials provided by American Academy of Neurology. Note: Materials may be edited for content and length.


Cite This Page:

American Academy of Neurology. "Children With Epilepsy Seizures May Benefit From New Animal Model Of Disease." ScienceDaily. ScienceDaily, 26 April 2007. <www.sciencedaily.com/releases/2007/04/070425164947.htm>.
American Academy of Neurology. (2007, April 26). Children With Epilepsy Seizures May Benefit From New Animal Model Of Disease. ScienceDaily. Retrieved October 1, 2014 from www.sciencedaily.com/releases/2007/04/070425164947.htm
American Academy of Neurology. "Children With Epilepsy Seizures May Benefit From New Animal Model Of Disease." ScienceDaily. www.sciencedaily.com/releases/2007/04/070425164947.htm (accessed October 1, 2014).

Share This



More Health & Medicine News

Wednesday, October 1, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Some Positive Ebola News: Outbreak 'Contained' In Nigeria

Some Positive Ebola News: Outbreak 'Contained' In Nigeria

Newsy (Sep. 30, 2014) The CDC says a new case of Ebola has not been reported in Nigeria for more than 21 days, leading to hopes the outbreak might be nearing its end. Video provided by Newsy
Powered by NewsLook.com
UN Ebola Mission Head: Immediate Action Is Crucial

UN Ebola Mission Head: Immediate Action Is Crucial

AFP (Sep. 30, 2014) The newly appointed head of the United Nations Mission for Ebola Emergency Response (UNMEER), Anthony Banbury, outlines operations to tackle the virus. Duration: 00:39 Video provided by AFP
Powered by NewsLook.com
CDC Confirms First Case of Ebola in US

CDC Confirms First Case of Ebola in US

AP (Sep. 30, 2014) The CDC has confirmed the first diagnosed case of Ebola in the United States. The patient is being treated at a Dallas hospital after traveling earlier this month from Liberia. (Sept. 30) Video provided by AP
Powered by NewsLook.com
New Breast Cancer Drug Extends Lives In Clinical Trial

New Breast Cancer Drug Extends Lives In Clinical Trial

Newsy (Sep. 30, 2014) In a clinical trial, breast cancer patients lived an average of 15 months longer when they received new drug Perjeta along with Herceptin. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins