Featured Research

from universities, journals, and other organizations

New Treatment For Fungi Which Cause Thrush And Sepsis

Date:
April 29, 2007
Source:
The Lancet
Summary:
A new treatment for Candida species of fungi which can cause thrush and sepsis (a life-threatening infection leading to fever, hypotension, and shock) has proven equally effective as the existing treatment in a drug trial. But the new drug has fewer side effects, claims an article published in The Lancet.

A new treatment for Candida species of fungi which can cause thrush and sepsis (a life-threatening infection leading to fever, hypotension, and shock) has proven equally effective as the existing treatment in a drug trial. But the new drug has fewer side effects, claims an article published in The Lancet.

Related Articles


Infections caused by Candida fungi have become increasingly prevalent in recent years, and problems associated with long established treatments are well known. Researchers led by Oliver Cornely, of The University Hospital of Cologne, Germany, tested the effectiveness of two well known treatments, liposomal amphotericin B and micafungin, against the common infections candidaemia and invasive candidosis.

A total of 531 patients with these infections were split into two groups and given either micafungin 100mg per day or liposomal amphotericin B 3mg per kg body weight daily. The success rate of both drugs was almost exactly the same – 89.6% for micofungin versus 89.6% for liposomal amphotericin B.

The effectiveness of either treatment was independent of primary site of infection and the patient’s immune status, and whether or not a catheter had been fitted during treatment.

But micafungin produced fewer treatment related side effects than liposomal amphotericin B. Increased problems with kidney function, as well as higher occurrence of problems during drug administration, were observed in the patients receiving liposomal amphotericin B.

The authors conclude: “Our results establish micafungin as a treatment option for first-line therapy of candidaemia and invasive candidosis.” They add: “Micafungin also has broad-spectrum activity against Aspergillosis spp, thus to assess its efficacy in the treatment of invasive aspergillosis will be an important future goal.”


Story Source:

The above story is based on materials provided by The Lancet. Note: Materials may be edited for content and length.


Cite This Page:

The Lancet. "New Treatment For Fungi Which Cause Thrush And Sepsis." ScienceDaily. ScienceDaily, 29 April 2007. <www.sciencedaily.com/releases/2007/04/070427111530.htm>.
The Lancet. (2007, April 29). New Treatment For Fungi Which Cause Thrush And Sepsis. ScienceDaily. Retrieved October 31, 2014 from www.sciencedaily.com/releases/2007/04/070427111530.htm
The Lancet. "New Treatment For Fungi Which Cause Thrush And Sepsis." ScienceDaily. www.sciencedaily.com/releases/2007/04/070427111530.htm (accessed October 31, 2014).

Share This



More Health & Medicine News

Friday, October 31, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

U.S. Ebola Response Measures Demonstrated

U.S. Ebola Response Measures Demonstrated

AP (Oct. 31, 2014) Officials in the Washington area showed off Ebola response measures being taken at Dulles International Airport and the National Institutes of Health. (Oct. 31) Video provided by AP
Powered by NewsLook.com
Fauci Says Ebola Risk in US "essentially Zero"

Fauci Says Ebola Risk in US "essentially Zero"

AP (Oct. 30, 2014) NIAID Director Anthony Fauci said the risk of Ebola becoming an epidemic in the U.S. is essentially zero Thursday at the Washington Ideas Forum. He also said an Ebola vaccine will be tested in West Africa in the next few months. (Oct. 30) Video provided by AP
Powered by NewsLook.com
Nurse Defies Ebola Quarantine With Bike Ride

Nurse Defies Ebola Quarantine With Bike Ride

AP (Oct. 30, 2014) A nurse who vowed to defy Maine's voluntary quarantine for health care workers who treated Ebola patients followed through on her promise Thursday, leaving her home for an hour-long bike ride. (Oct. 30) Video provided by AP
Powered by NewsLook.com
Pot-Infused Edibles Raise Concerns in Colorado

Pot-Infused Edibles Raise Concerns in Colorado

AFP (Oct. 30, 2014) Colorado may have legalized marijuana for recreational use, but the debate around the decision still continues, with a recent - failed - attempt to ban cannabis-infused edibles. Duration: 01:53 Video provided by AFP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins