Featured Research

from universities, journals, and other organizations

Subtle Signs Can Help Predict Huntington's Disease Early

Date:
May 15, 2007
Source:
American Academy of Neurology
Summary:
Subtle signs can help doctors predict that a person will develop Huntington's disease in the next few years, according to a new study. Huntington's disease is a genetic disorder that affects movement, thinking, and some aspects of personality. There is no treatment or cure for the disease.

Subtle signs can help doctors predict that a person will develop Huntington's disease in the next few years, according to a study published in the May 15, 2007, issue of Neurology®, the scientific journal of the American Academy of Neurology. Huntington's disease is a genetic disorder that affects movement, thinking, and some aspects of personality. There is no treatment or cure for the disease.

"These results will help us understand how and who will develop Huntington's, which is important information as potential treatments are developed," said study author Jane S. Paulsen, PhD, of the University of Iowa Roy J. and Lucille A. Carver College of Medicine in Iowa City. "Ideally, treatments will target at-risk people at or before the earliest stages of the disease, before they have any problems with thinking or movement."

The study involved 218 people in North America, Europe and Australia considered at risk for Huntington's disease because they had at least one parent with the disease. If a parent has the disease, there is a 50-percent chance that the child will develop the disease.

The participants were healthy at the beginning of the study, with normal scores on movement tests or minimal signs of movement problems. They were then followed for up to 4.5 years. Those with minimal motor problems at the beginning of the study were nearly five times more likely to be diagnosed with the disease a year and a half later than those who had no movement problems initially. They were 3.5 times more likely to be diagnosed with the disease after three years.

Researchers also tested cognitive abilities. For a verbal fluency test, they were given a letter of the alphabet and 60 seconds to say as many words as they could starting with that letter. They were also tested on how quickly they could combine thinking and movement, or "psychomotor speed," with a memory and writing task. Those who performed worse on the psychomotor test than on the verbal fluency test were twice as likely to be diagnosed with Huntington's disease a year and a half later than those whose tests scores were equivalent.

The study was supported by grants from the National Institute of Neurological Disorders and Stroke, the National Institute of Mental Health, the Roy J. and Lucille Carver Trust, the Howard Hughes Medical Institute, the High Q Foundation, the Huntington's Disease Society of America, the Huntington's Society of Canada, and the Hereditary Disease Foundation.


Story Source:

The above story is based on materials provided by American Academy of Neurology. Note: Materials may be edited for content and length.


Cite This Page:

American Academy of Neurology. "Subtle Signs Can Help Predict Huntington's Disease Early." ScienceDaily. ScienceDaily, 15 May 2007. <www.sciencedaily.com/releases/2007/05/070514174300.htm>.
American Academy of Neurology. (2007, May 15). Subtle Signs Can Help Predict Huntington's Disease Early. ScienceDaily. Retrieved July 26, 2014 from www.sciencedaily.com/releases/2007/05/070514174300.htm
American Academy of Neurology. "Subtle Signs Can Help Predict Huntington's Disease Early." ScienceDaily. www.sciencedaily.com/releases/2007/05/070514174300.htm (accessed July 26, 2014).

Share This




More Mind & Brain News

Saturday, July 26, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

University Quiz Implies Atheists Are Smarter Than Christians

University Quiz Implies Atheists Are Smarter Than Christians

Newsy (July 25, 2014) — An online quiz from a required course at Ohio State is making waves for suggesting atheists are inherently smarter than Christians. Video provided by Newsy
Powered by NewsLook.com
Beatings and Addiction: Pakistan Drug 'clinic' Tortures Patients

Beatings and Addiction: Pakistan Drug 'clinic' Tortures Patients

AFP (July 24, 2014) — A so-called drugs rehab 'clinic' is closed down in Pakistan after police find scores of ‘patients’ chained up alleging serial abuse. Duration 03:05 Video provided by AFP
Powered by NewsLook.com
New Painkiller Designed To Discourage Abuse: Will It Work?

New Painkiller Designed To Discourage Abuse: Will It Work?

Newsy (July 24, 2014) — The FDA approved Targiniq ER on Wednesday, a painkiller designed to keep users from abusing it. Like any new medication, however, it has doubters. Video provided by Newsy
Powered by NewsLook.com
Can Watching TV Make You Feel Like A Failure?

Can Watching TV Make You Feel Like A Failure?

Newsy (July 24, 2014) — A study by German researchers claims watching TV while you're stressed out can make you feel guilty and like a failure. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins