Featured Research

from universities, journals, and other organizations

Men And Women Equally Transmit Genetic Risk Of Multiple Sclerosis To Their Children

Date:
June 29, 2007
Source:
American Academy of Neurology
Summary:
Men and women with multiple sclerosis (MS) equally transmit the genetic risk of the disease to their children, according to a new study. The research contradicts the results of another recent study, which found affected fathers were more likely than affected mothers to transmit the risk of developing MS to their children.

Men and women with multiple sclerosis (MS) equally transmit the genetic risk of the disease to their children, according to a study published June 27, 2007, in the online edition of Neurology®, the medical journal of the American Academy of Neurology. The research contradicts the results of a recent study, which found affected fathers were more likely than affected mothers to transmit the risk of developing MS to their children.

Related Articles


Researchers studied 3,088 Canadian families with one parent affected with MS. Of the 8,401 children in those families, 798 had MS.

The study found equal transmission of the genetic risk of MS to children with 9.41 percent of fathers transmitting MS to their children compared to 9.76 percent of mothers.

"We also found there were equal numbers of daughters and sons receiving the genetic risk of the disease from their parents," said study author George Ebers, MD, FMedSci, Action Research Professor of Clinical Neurology at the University of Oxford. "Intriguingly, we also found when half siblings both have MS, there is a clear maternal effect with mothers much more likely to be the common parent."

Ebers says the findings show no evidence of the Carter effect, which was recently cited in a study that found men with MS were twice as likely to pass the risk of disease on to their children. According to the Carter effect, men are more resistant to MS because they carry a higher genetic load and thus are more likely to transmit the genetic risk of the disease to their children.

"Our study involved 16 times as many people as the previous published study. It casts further doubt on the widely believed multiple gene mode of inheritance of susceptibility to MS," said Ebers.

The study was supported by the Multiple Sclerosis Society of Canada Scientific Research Foundation.


Story Source:

The above story is based on materials provided by American Academy of Neurology. Note: Materials may be edited for content and length.


Cite This Page:

American Academy of Neurology. "Men And Women Equally Transmit Genetic Risk Of Multiple Sclerosis To Their Children." ScienceDaily. ScienceDaily, 29 June 2007. <www.sciencedaily.com/releases/2007/06/070627161805.htm>.
American Academy of Neurology. (2007, June 29). Men And Women Equally Transmit Genetic Risk Of Multiple Sclerosis To Their Children. ScienceDaily. Retrieved January 31, 2015 from www.sciencedaily.com/releases/2007/06/070627161805.htm
American Academy of Neurology. "Men And Women Equally Transmit Genetic Risk Of Multiple Sclerosis To Their Children." ScienceDaily. www.sciencedaily.com/releases/2007/06/070627161805.htm (accessed January 31, 2015).

Share This


More From ScienceDaily



More Mind & Brain News

Saturday, January 31, 2015

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

NFL Concussions Down; Still on Parents' Minds

NFL Concussions Down; Still on Parents' Minds

AP (Jan. 30, 2015) — The NFL announced this week that the number of game concussions dropped by a quarter over last season. Still, the dangers of the sport still weigh on players, and parents&apos; minds. (Jan. 30) Video provided by AP
Powered by NewsLook.com
Study Shows Newborn Chicks Count From Left to Right Just Like Humans

Study Shows Newborn Chicks Count From Left to Right Just Like Humans

Buzz60 (Jan. 30, 2015) — Researchers for the first time identified human&apos;s innate preference for associating low and high numbers with the left and right respectively in another species. Jen Markham (@jenmarkham) explains. Video provided by Buzz60
Powered by NewsLook.com
Best Mood Elevating, Feel Good Shakes & Smoothies

Best Mood Elevating, Feel Good Shakes & Smoothies

Buzz60 (Jan. 30, 2015) — You can elevate your mood by having a meal in a glass. Fitness and nutrition expert John Basedow (@JohnBasedow) offers the best &apos;feel good&apos; smoothies and shakes chock full of depression-relieving ingredients...including apples, berries, lemons, cucumbers, papaya, kiwi, spinach, kale, whey protein, matcha, ginger, turmeric and cinnamon. Video provided by Buzz60
Powered by NewsLook.com
Poll Says Firstborn Is Responsible, Youngest Is Funnier

Poll Says Firstborn Is Responsible, Youngest Is Funnier

Newsy (Jan. 30, 2015) — According to a poll out of the U.K., eldest siblings feel more responsible and successful than their younger siblings. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:

Strange & Offbeat Stories

 

Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins