Featured Research

from universities, journals, and other organizations

Infection Contributes To The High Rates Of Oropharyngeal Cancers

Date:
August 28, 2007
Source:
John Wiley & Sons, Inc.
Summary:
A review finds an increasing trend in the incidence of oropharyngeal cancers, particularly among men under 45 years old, for which HPV infection is the likely cause. Cancers of the head and neck, which include cancers of the larynx, nasal passages/nose, oral cavity, pharynx, and salivary glands, account for three percent of all newly diagnosed cancers in the U.S. Men are three times more likely to be diagnosed with these cancers than women.

Though the overall incidence of head and neck cancers has fallen in the United States, the rate of oropharyngeal (chiefly, tonsil and base of tongue) cancers is stagnant and appears to be rising is certain populations and these trends are likely due to oncogenic human papillomavirus (HPV) infection.

Related Articles


A review published in the journal Cancer, finds an increasing trend in the incidence of oropharyngeal cancers, particularly among men under 45 years old, for which HPV infection is the likely cause.

Cancers of the head and neck, which include cancers of the larynx, nasal passages/nose, oral cavity, pharynx, and salivary glands, account for three percent of all newly diagnosed cancers in the U.S. Men are three times more likely to be diagnosed with these cancers than women.

Of the estimated 45,000 new cases of head and neck cancers expected this year, approximately 10,000 are cancers of the pharynx (chiefly the oropharynx). Though the prognosis for these cancers is excellent when caught early, more than half of them are identified in advanced stages, when the prognosis is far worse, making prevention critical to saving lives.

In their review, Erich M. Sturgis, M.D., M.P.H. and Paul Cinciripini, Ph.D. of The University of Texas M. D. Anderson Cancer Center in Houston, conclude that the stagnate incidence rates of oropharyngeal cancers, particularly cancers of the tonsil and base of tongue, in the face of declines in tobacco use, the principal cause of head and neck cancers, are likely explained by rising prevalence of oropharyngeal exposure to an oncogenic virus.

They say the literature points to exposure to HPV -- especially strain 16 -- as having the strongest association to oropharyngeal cancers. However, the authors suggest that a recently approved HPV vaccine may ultimately have a significant impact on the incidence of oropharyngeal tumors.

"While the cervical cancer and dysplasia prevention policy of HPV16/18 vaccination of young women and adolescent females are commended, we fear that vaccination programs limited to females will only delay the potential benefit in prevention of HPV16/18 associated oropharyngeal cancers, which typically occur in men," conclude the authors.

The authors "encourage the rapid study of the efficacy and safety of these vaccines in males and, if successful, the recommendation of vaccination of young adult and adolescent males."

Article: "Trends in Head and Neck Cancer Incidence in Relation to Smoking Prevalence: An Emerging Epidemic of Human Papillomavirus-Associated Cancers"," Erich M. Sturgis, M.D., M.P.H., and Paul M. Cinciripini, Cancer; Published Online: August 27, 2007 (DOI: 10.1002/cncr. 22963); Print Issue Date: October 1, 2007.


Story Source:

The above story is based on materials provided by John Wiley & Sons, Inc.. Note: Materials may be edited for content and length.


Cite This Page:

John Wiley & Sons, Inc.. "Infection Contributes To The High Rates Of Oropharyngeal Cancers." ScienceDaily. ScienceDaily, 28 August 2007. <www.sciencedaily.com/releases/2007/08/070827095218.htm>.
John Wiley & Sons, Inc.. (2007, August 28). Infection Contributes To The High Rates Of Oropharyngeal Cancers. ScienceDaily. Retrieved November 25, 2014 from www.sciencedaily.com/releases/2007/08/070827095218.htm
John Wiley & Sons, Inc.. "Infection Contributes To The High Rates Of Oropharyngeal Cancers." ScienceDaily. www.sciencedaily.com/releases/2007/08/070827095218.htm (accessed November 25, 2014).

Share This


More From ScienceDaily



More Health & Medicine News

Tuesday, November 25, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

From Popcorn To Vending Snacks: FDA Ups Calorie Count Rules

From Popcorn To Vending Snacks: FDA Ups Calorie Count Rules

Newsy (Nov. 25, 2014) The US FDA is announcing new calorie rules on Tuesday that will require everywhere from theaters to vending machines to include calorie counts. Video provided by Newsy
Powered by NewsLook.com
Madagascar Working to Contain Plague Outbreak

Madagascar Working to Contain Plague Outbreak

AFP (Nov. 24, 2014) Madagascar said Monday it is trying to contain an outbreak of plague -- similar to the Black Death that swept Medieval Europe -- that has killed 40 people and is spreading to the capital Antananarivo. Duration: 00:42 Video provided by AFP
Powered by NewsLook.com
Are Female Bosses More Likely To Be Depressed?

Are Female Bosses More Likely To Be Depressed?

Newsy (Nov. 24, 2014) A new study links greater authority with increased depressive symptoms among women in the workplace. Video provided by Newsy
Powered by NewsLook.com
Winter Can Cause Depression — Here's How To Combat It

Winter Can Cause Depression — Here's How To Combat It

Newsy (Nov. 23, 2014) Millions of American suffer from seasonal depression every year. It can lead to adverse health effects, but there are ways to ease symptoms. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins