Featured Research

from universities, journals, and other organizations

Predicting Cardiovascular Disease Risk For Rheumatoid Arthritis Patients

Date:
November 11, 2007
Source:
Mayo Clinic
Summary:
People with rheumatoid arthritis have a higher risk for developing heart disease than the general population; however, it is difficult to identify which patients are at increased risk. Researchers have developed a simple approach to predict heart disease in these patients within 10 years of their initial diagnosis of rheumatoid arthritis.

People with rheumatoid arthritis have a higher risk for developing heart disease than the general population; however, it is difficult to identify which patients are at increased risk. Researchers at Mayo Clinic have developed a simple approach to predict heart disease in these patients within ten years of their initial diagnosis of rheumatoid arthritis.

Previous research by the Mayo Clinic team identified a link between rheumatoid arthritis patients and increased risk for heart disease. A major challenge for physicians is detection and prevention of heart disease in rheumatoid arthritis patients who show no symptoms of heart disease. The goal of this latest study is to find a way to detect the risk of heart disease earlier in patients with rheumatoid arthritis.

"Rheumatoid arthritis sufferers are dealing with significant pain and stress, therefore cardiovascular disease prevention may be delayed," says Hilal Maradit Kremers, M.D., lead study investigator and research associate in the Mayo Clinic Department of Health Sciences Research, "Our findings indicate that evaluation of cardiovascular risk based on risk factor profiles of individual patients can help physicians identify high risk rheumatoid arthritis patients and assist with decisions concerning cardiovascular disease prevention."

Mayo Clinic researchers estimated the 10-year absolute risk of cardiovascular disease in a group of 553 patients diagnosed with rheumatoid arthritis and compared them with 574 patients of the same age and gender who did not have rheumatoid arthritis. The researchers collected detailed information about all study subjects' cardiac events and their traditional cardiovascular risk factors: diabetes, blood pressure, cholesterol, body mass index and smoking.

Using absolute risk analysis methods, researchers discovered that 85 percent of those 60 to 69 year olds who were newly diagnosed with rheumatoid arthritis patients had a 1 in 5 chance of developing a serious cardiovascular event, compared to only 40 percent of patients who did not have rheumatoid arthritis. In each age group, cardiovascular risk in rheumatoid arthritis patients was similar to that of nonrheumatoid arthritis subjects who were 5-10 years older.

"These results emphasize the importance of performing a comprehensive cardiovascular risk assessment for all newly diagnosed rheumatoid arthritis patients," says Sherine Gabriel, M.D., the study's senior author and Mayo Clinic rheumatologist and epidemiologist.

Rheumatoid arthritis is a chronic, autoimmune disease that causes pain, swelling, stiffness and loss of function in multiple joints. Rheumatoid arthritis is a systemic disease and also may affect other organs of the body including the lungs, heart and kidneys. Rheumatoid arthritis affects about 2.1 million Americans, mostly women and generally striking between the ages of 20 and 50.

The findings of this Mayo Clinic research study are being presented at the American College of Rheumatology Annual Scientific Meeting in Boston, Nov. 6-11, 2007.

Members of the Mayo Clinic study team include: Hilal Maradit-Kremers, M.D., Cynthia Crowson, Terry Therneau, Ph.D; Veronique Roger, M.D., and Sherine Gabriel, M.D. Their work was supported by grants from the National Institutes of Health; in particular, the National Institute of Arthritis and Musculoskeletal and Skin Diseases.


Story Source:

The above story is based on materials provided by Mayo Clinic. Note: Materials may be edited for content and length.


Cite This Page:

Mayo Clinic. "Predicting Cardiovascular Disease Risk For Rheumatoid Arthritis Patients." ScienceDaily. ScienceDaily, 11 November 2007. <www.sciencedaily.com/releases/2007/11/071107181025.htm>.
Mayo Clinic. (2007, November 11). Predicting Cardiovascular Disease Risk For Rheumatoid Arthritis Patients. ScienceDaily. Retrieved July 22, 2014 from www.sciencedaily.com/releases/2007/11/071107181025.htm
Mayo Clinic. "Predicting Cardiovascular Disease Risk For Rheumatoid Arthritis Patients." ScienceDaily. www.sciencedaily.com/releases/2007/11/071107181025.htm (accessed July 22, 2014).

Share This




More Health & Medicine News

Tuesday, July 22, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Gilead's $1000-a-Pill Drug Could Cure Hep C in HIV-Positive People

Gilead's $1000-a-Pill Drug Could Cure Hep C in HIV-Positive People

TheStreet (July 21, 2014) New research shows Gilead Science's drug Sovaldi helps in curing hepatitis C in those who suffer from HIV. In a medical study, the combination of Gilead's Hep C drug with anti-viral drug Ribavirin cured 76% of HIV-positive patients suffering from the most common hepatitis C strain. Hepatitis C and related complications have been a top cause of death in HIV-positive patients. Typical medication used to treat the disease, including interferon proteins, tended to react badly with HIV drugs. However, Sovaldi's %1,000-a-pill price tag could limit the number of patients able to access the treatment. TheStreet's Keris Lahiff reports from New York. Video provided by TheStreet
Powered by NewsLook.com
$23.6 Billion Awarded To Widow In Smoking Lawsuit

$23.6 Billion Awarded To Widow In Smoking Lawsuit

Newsy (July 20, 2014) Cynthia Robinson claims R.J. Reynolds Tobacco Company hid the health and addiction risks of its products, leading to the death of her husband in 1996. Video provided by Newsy
Powered by NewsLook.com
Tooth Plaque Provides Insight Into Diets Of Ancient People

Tooth Plaque Provides Insight Into Diets Of Ancient People

Newsy (July 19, 2014) Research on plaque from ancient teeth shows that our prehistoric ancestor's had a detailed understanding of plants long before developing agriculture. Video provided by Newsy
Powered by NewsLook.com
Contaminated Water Kills 3 Babies in South African Town

Contaminated Water Kills 3 Babies in South African Town

AFP (July 18, 2014) Contaminated water in South Africa's northwestern town of Bloemhof kills three babies and hospitalises over 500 people. The incident highlights growing fears over water safety in South Africa. Duration: 02:22 Video provided by AFP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins