Featured Research

from universities, journals, and other organizations

Brain Compensatory Mechanisms Enhance The Recovery From Spinal Cord Injury

Date:
November 17, 2007
Source:
National Institute for Physiological Sciences
Summary:
Brain compensatory mechanisms contribute to recovery from spinal cord injury. The basis of neurorehabilitation relies on the concept that training recruits remaining intact neuronal systems to compensate for partial injury to the spinal cord or brain.

A research team led by Tadashi Isa, a professor at the Japanese National Institute for Physiological Sciences, NIPS (SEIRIKEN), and Dr. Yukio Nishimura (University of Washington, Seattle), have found that brain compensatory mechanisms contribute to recovery from spinal cord injury.

The basis of neurorehabilitation relies on the concept that training recruits remaining intact neuronal systems to compensate for partial injury to the spinal cord or brain. Until recently, the neuronal basis of these compensatory mechanisms has been poorly understood. In previous work, the research team showed that finger dexterity could recover with rehabilitation following transection of the direct cortico-motoneuronal pathway in the Japanese macaque monkey.

In the current study, brain imaging (PET scan) indicated that bilateral primary motor cortex contributes to early-stage recovery of finger movement. During late-stage recovery, more extensive regions of the contralesional primary motor cortex and bilateral premotor cortex were activated to compensate for impaired finger movements.

Pharmacological inactivation of these regions during rehabilitation slowed recovery. These results suggest that brain compensatory mechanisms actively enhance recovery from spinal cord injury.

Professor Isa explains that this study is the first to show that brain compensatory mechanisms contribute to recovery following injury to the central nervous system. The functional plasticity of the brain compensates for lost function and enhances recovery from injury. "This study reinforces our current understanding of neurorehabilitation and may lead to new rehabilitation strategies for patients with spinal cord injuries or any kind of brain damage", said Professor Isa.

This study was conducted in collaboration with Hamamatsu Photonics (Dr. Hideo Tsukada) and RIKEN (Dr. Hirotaka Onoe). It was supported by the Japan Science and Technology Agency (JST). The team reports their findings on November 16, 2007 in the journal Science.


Story Source:

The above story is based on materials provided by National Institute for Physiological Sciences. Note: Materials may be edited for content and length.


Cite This Page:

National Institute for Physiological Sciences. "Brain Compensatory Mechanisms Enhance The Recovery From Spinal Cord Injury." ScienceDaily. ScienceDaily, 17 November 2007. <www.sciencedaily.com/releases/2007/11/071115164503.htm>.
National Institute for Physiological Sciences. (2007, November 17). Brain Compensatory Mechanisms Enhance The Recovery From Spinal Cord Injury. ScienceDaily. Retrieved September 18, 2014 from www.sciencedaily.com/releases/2007/11/071115164503.htm
National Institute for Physiological Sciences. "Brain Compensatory Mechanisms Enhance The Recovery From Spinal Cord Injury." ScienceDaily. www.sciencedaily.com/releases/2007/11/071115164503.htm (accessed September 18, 2014).

Share This



More Health & Medicine News

Thursday, September 18, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Artificial Sweetener Could Promote Diabetes

Artificial Sweetener Could Promote Diabetes

Newsy (Sep. 17, 2014) Doctors once thought artificial sweeteners lacked the health risks of sugar, but a new study says they can impact blood sugar levels the same way. Video provided by Newsy
Powered by NewsLook.com
Ebola Vaccine Trial Gets Underway at Oxford University

Ebola Vaccine Trial Gets Underway at Oxford University

AFP (Sep. 17, 2014) A healthy British volunteer is to become the first person to receive a new vaccine for the Ebola virus after US President Barack Obama called for action against the epidemic and warned it was "spiralling out of control." Duration: 01:02 Video provided by AFP
Powered by NewsLook.com
Obesity Rates Steady Even As Americans' Waistlines Expand

Obesity Rates Steady Even As Americans' Waistlines Expand

Newsy (Sep. 17, 2014) Researchers are puzzled as to why obesity rates remain relatively stable as average waistlines continue to expand. Video provided by Newsy
Powered by NewsLook.com
President To Send 3,000 Military Personnel To Fight Ebola

President To Send 3,000 Military Personnel To Fight Ebola

Newsy (Sep. 16, 2014) President Obama is expected to send 3,000 troops to West Africa as part of the effort to contain Ebola's spread. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins