Featured Research

from universities, journals, and other organizations

Antioxidants Do Not Help Children With Down's Syndrome Develop, Study Shows

Date:
February 25, 2008
Source:
British Medical Journal
Summary:
Giving children with Down's syndrome antioxidants and nutrients does not help their condition improve at all, according to a new study. UK researchers studied the effect of giving such supplements to 156 babies under 7 months old with Down's syndrome over an 18-month period. Down's syndrome is the most common genetic cause of learning disability in the UK affecting around 1 in 1,000 new born babies. Previous studies have investigated the possibility that giving folate, antioxidants, or both might improve the effects of Down's syndrome, particularly language and psychomotor development. Although none have reported any significant effect, use of vitamin and mineral supplements is widespread in children with Down's syndrome in Europe and the USA due to marketing of commercial preparations claiming substantial benefits.

Giving children with Down’s syndrome antioxidants and nutrients does not help their condition improve at all, according to a study published today on bmj.com.

Related Articles


UK researchers studied the effect of giving such supplements to 156 babies under 7 months old with Down’s syndrome over an 18-month period.

Down’s syndrome is the most common genetic cause of learning disability in the UK affecting around 1 in 1,000 new born babies.

Previous studies have investigated the possibility that giving folate, antioxidants, or both might improve the effects of Down’s syndrome, particularly language and psychomotor development.

Although none have reported any significant effect, use of vitamin and mineral supplements is widespread in children with Down’s syndrome in Europe and the USA due to marketing of commercial preparations claiming substantial benefits.

In this study, the babies, from several sites in England, were split into four groups. One group was given a daily dose of antioxidants, one folinic acid, one a combination of antioxidants and folinic acid, and one a placebo. All the supplements were given in a powder that could be mixed with food or drink.

After 18 months, the children remaining in the study were assessed for their mental and cognitive development.

The researchers found that giving the supplements made no difference to the biochemical outcomes in the children and did not improve their language or psychomotor development.

This study provides no evidence to support the use of antioxidant or folinic acid supplements in children with Down’s syndrome, conclude the authors. Parents who choose to give supplements to their children need to weigh their hope of unproved benefits against potential adverse effects from high dose, prolonged supplementation.

These findings are supported in an accompanying editorial, which states that until evidence of any benefit of expensive vitamin supplements is available, they cannot be recommended.

Journal article:http://press.psprings.co.uk/bmj/february/Downs.pdf


Story Source:

The above story is based on materials provided by British Medical Journal. Note: Materials may be edited for content and length.


Cite This Page:

British Medical Journal. "Antioxidants Do Not Help Children With Down's Syndrome Develop, Study Shows." ScienceDaily. ScienceDaily, 25 February 2008. <www.sciencedaily.com/releases/2008/02/080223123616.htm>.
British Medical Journal. (2008, February 25). Antioxidants Do Not Help Children With Down's Syndrome Develop, Study Shows. ScienceDaily. Retrieved March 27, 2015 from www.sciencedaily.com/releases/2008/02/080223123616.htm
British Medical Journal. "Antioxidants Do Not Help Children With Down's Syndrome Develop, Study Shows." ScienceDaily. www.sciencedaily.com/releases/2008/02/080223123616.htm (accessed March 27, 2015).

Share This


More From ScienceDaily



More Health & Medicine News

Friday, March 27, 2015

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

House Ready to Pass Medicare Doc Bill

House Ready to Pass Medicare Doc Bill

AP (Mar. 26, 2015) In rare bipartisan harmony, congressional leaders pushed a $214 billion bill permanently blocking physician Medicare cuts toward House passage Thursday, moving lawmakers closer to resolving a problem that has plagued them for years. (March 26) Video provided by AP
Powered by NewsLook.com
HIV Outbreak Prompts Public Health Emergency In Indiana

HIV Outbreak Prompts Public Health Emergency In Indiana

Newsy (Mar. 26, 2015) Indiana Gov. Mike Pence says he will bring additional state resources to help stop the epidemic. Video provided by Newsy
Powered by NewsLook.com
Indiana Permits Needle Exchange as HIV Cases Skyrocket

Indiana Permits Needle Exchange as HIV Cases Skyrocket

Reuters - US Online Video (Mar. 26, 2015) Governor Mike Pence declares the recent HIV outbreak in rural Indiana a "public health emergency" and authorizes a short-term needle-exchange program. Rough Cut (no reporter narration) Video provided by Reuters
Powered by NewsLook.com
AAA: Distracted Driving a Serious Teen Problem

AAA: Distracted Driving a Serious Teen Problem

AP (Mar. 25, 2015) While distracted driving is not a new problem for teens, new research from the AAA Foundation for Traffic Safety says it&apos;s much more serious than previously thought. (March 25) Video provided by AP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins