Featured Research

from universities, journals, and other organizations

Pregnant Mothers' Diet Linked To Baby's Obesity, Study Suggests

Date:
April 7, 2008
Source:
BioMed Central/Lipids in Health and Disease
Summary:
Rats eating trans-fatty acid while pregnant or breastfeeding have fatter babies. The unhealthy diet has deleterious consequences even after the fats were removed from the diet and has links to insulin production.

Pregnant and lactating rats fed on a diet of hydrogenated fat during pregnancy and lactation had babies who were fatter than rats fed a normal diet, according to new research. The unhealthy diet has deleterious consequences even after the fats were removed from the diet and has links to insulin production.

"We know that foetal growth is influenced by the mother's nutritional status," explained Brazilian nutritionist Luciana Pisani. "The nutritional conditions during pregnancy has a major role in the metabolic and hormonal interactions between the mother's body, placenta and foetus. To date only a few studies have looked at the effects on trans fatty acids during pregnancy and lactation on the metabolism of offspring in adulthood. We found that the fatty content of the babies' bodies increased when the mothers were fed the hydrogenated fat rich diet and this could be traced to the gene expression of adipokines."

In an investigation to examine whether feeding pregnant and lactating rats hydrogenised fats rich in trans fatty acids, increased the fat content in carcass, the researchers found that their metabolic rate dropped dramatically. Interestingly young rats that were fed a normal diet after they were born ate less and weighed less even though their mothers had been eating the trans fatty acids while pregnant. The gene expression of adipokines was also examined in relation to insulin production.

The offspring were weighed weekly and exposure to the trans-fatty acid enriched diet after weaning led to a 40% increase in body fat content for the young rats. Rats whose mothers were fed the trans fatty acids and continued to eat the fats into adulthood had the highest metabolic efficiency. The same rats increased their insulin production.

Pisani continued, "Fats play a fundamental role in foetal development and changes in dietary fatty acids has important implications for foetal and postnatal development. Heavy ingestion of very hydrogenated fats rich in trans fatty acids increases risk of cardiovascular diseases and reduces insulin sensitivity and so leads to type 2 diabetes. We need to investigate this further as this has important implications for people's own diets, especially pregnant women."

Journal reference: Hydrogenated fat diet intake during pregnancy and lactation modifies the PAI-1 gene expression in white adipose tissue of offspring in adult. Lipids in Health and Disease (in press).


Story Source:

The above story is based on materials provided by BioMed Central/Lipids in Health and Disease. Note: Materials may be edited for content and length.


Cite This Page:

BioMed Central/Lipids in Health and Disease. "Pregnant Mothers' Diet Linked To Baby's Obesity, Study Suggests." ScienceDaily. ScienceDaily, 7 April 2008. <www.sciencedaily.com/releases/2008/04/080403202751.htm>.
BioMed Central/Lipids in Health and Disease. (2008, April 7). Pregnant Mothers' Diet Linked To Baby's Obesity, Study Suggests. ScienceDaily. Retrieved September 21, 2014 from www.sciencedaily.com/releases/2008/04/080403202751.htm
BioMed Central/Lipids in Health and Disease. "Pregnant Mothers' Diet Linked To Baby's Obesity, Study Suggests." ScienceDaily. www.sciencedaily.com/releases/2008/04/080403202751.htm (accessed September 21, 2014).

Share This



More Health & Medicine News

Sunday, September 21, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Sierra Leone's Nationwide Ebola Curfew Underway

Sierra Leone's Nationwide Ebola Curfew Underway

Newsy (Sep. 20, 2014) Sierra Leone is locked down as aid workers and volunteers look for new cases of Ebola. Video provided by Newsy
Powered by NewsLook.com
Changes Found In Brain After One Dose Of Antidepressants

Changes Found In Brain After One Dose Of Antidepressants

Newsy (Sep. 19, 2014) A study suggest antidepressants can kick in much sooner than previously thought. Video provided by Newsy
Powered by NewsLook.com
Could Grief Affect The Immune Systems Of Senior Citizens?

Could Grief Affect The Immune Systems Of Senior Citizens?

Newsy (Sep. 19, 2014) The study found elderly people are much more likely to become susceptible to infection than younger adults going though a similar situation. Video provided by Newsy
Powered by NewsLook.com
Jury Delivers Verdict in Salmonella Trial

Jury Delivers Verdict in Salmonella Trial

AP (Sep. 19, 2014) A federal jury has convicted three people in connection with an outbreak of salmonella poisoning five years ago that sickened hundreds of people and was linked to a number of deaths. (Sept. 19) Video provided by AP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins