Featured Research

from universities, journals, and other organizations

Drug Can Reduce Leg Pain Caused By Narrowed Arteries

Date:
April 18, 2008
Source:
Wiley-Blackwell
Summary:
Patients with pain caused by narrowed arteries in their legs have 37 percent more pain-free walking if they take naftidrofuryl (200 mg three times a day) than those taking placebos, a Cochrane Review has found. In addition, 55 percent of patients taking naftidrofuryl improved, while only 30 percent of people on placebo treatments improved. Naftidrofuryl is used to treat circulatory problems.

Patients with pain caused by narrowed arteries in their legs have 37% more pain-free walking if they take naftidrofuryl (200mg three times a day) than those taking placebos, a Cochrane Review has found. In addition, 55% of patients taking naftidrofuryl improved, while only 30% of people on placebo treatments improved. Naftidrofuryl is used to treat circulatory problems.

Cochrane Researchers came to this conclusion after identifying seven studies in which a total of 1266 patient had been treated for at least three months. They analysed the data by retrieving and pooling the original patient data.

The symptoms of intermittent claudication are pain, cramp or a sense of fatigue in leg muscles that increases on exercise such as walking, but goes away when the person rests. The condition affects less than 1% of people below the age of 49, but increases to over 5% of those aged 70 and older. The problem is that the arteries supplying the legs have hardened and narrowed due to fatty deposits. This makes it less easy for blood to carry oxygen and nutrients to the muscles or clear waste products away.

While stopping smoking and gently increasing exercise can reduce symptoms, interest has also been focused on some pharmaceutical products. Naftidrofuryl has been on the market since 1968 and has a good safety record. Its patent has expired, so there are many generic options in most countries.

"It would make sense to give naftidrofuryl alongside recommending lifestyle changes such as stopping smoking, physical exercise and also prescribing anti-platelet drugs and statins" says lead researcher Dr Tine de Backer who works at the Heymans Institute of Pharmacology in Gent, Belgium.

 


Story Source:

The above story is based on materials provided by Wiley-Blackwell. Note: Materials may be edited for content and length.


Cite This Page:

Wiley-Blackwell. "Drug Can Reduce Leg Pain Caused By Narrowed Arteries." ScienceDaily. ScienceDaily, 18 April 2008. <www.sciencedaily.com/releases/2008/04/080415194401.htm>.
Wiley-Blackwell. (2008, April 18). Drug Can Reduce Leg Pain Caused By Narrowed Arteries. ScienceDaily. Retrieved April 25, 2014 from www.sciencedaily.com/releases/2008/04/080415194401.htm
Wiley-Blackwell. "Drug Can Reduce Leg Pain Caused By Narrowed Arteries." ScienceDaily. www.sciencedaily.com/releases/2008/04/080415194401.htm (accessed April 25, 2014).

Share This



More Health & Medicine News

Friday, April 25, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Deadly Fungus Killing Bats, Spreading in US

Deadly Fungus Killing Bats, Spreading in US

AP (Apr. 24, 2014) — A disease that has killed more than six million cave-dwelling bats in the United States is on the move and wildlife biologists are worried. White Nose Syndrome, discovered in New York in 2006, has now spread to 25 states. (April 24) Video provided by AP
Powered by NewsLook.com
Companies Ramp Up Wellness to Lower Health Costs

Companies Ramp Up Wellness to Lower Health Costs

AP (Apr. 24, 2014) — That little voice telling you to exercise, get in shape and get healthy is probably coming from your boss. More companies are beefing up wellness programs to try and cut down their health care costs. (April 24) Video provided by AP
Powered by NewsLook.com
Blood From World's Oldest Woman Suggests Life Limit

Blood From World's Oldest Woman Suggests Life Limit

Newsy (Apr. 24, 2014) — Scientists say for the extremely elderly, their stem cells might reach a state of exhaustion. This could limit one's life span. Video provided by Newsy
Powered by NewsLook.com
FDA Wants To Ban Sales Of E-Cigarettes To Minors

FDA Wants To Ban Sales Of E-Cigarettes To Minors

Newsy (Apr. 24, 2014) — The Food and Drug Administration wants to crack down on the use of e-cigarettes, banning the sale of the product to minors. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins