Featured Research

from universities, journals, and other organizations

New Method Simultaneously Tests For Fifteen Respiratory Viruses

Date:
April 27, 2008
Source:
American Society for Microbiology
Summary:
A new test capable of simultaneously detecting 15 respiratory viruses may allow for quicker diagnosis and treatment of potentially deadly respiratory infections in children and adults worldwide.

A new test capable of simultaneously detecting 15 respiratory viruses may allow for quicker diagnosis and treatment of potentially deadly respiratory infections in children and adults worldwide.

Acute respiratory infections (RTIs) are responsible for high rates of morbidity and mortality throughout the world, however the cause remains inconclusive in over half of all reported cases. Respiratory viruses are believed to be among the pathogens contributing to a significant number of undiagnosed infections, but clinical presentation of patients with RTIs are generally not pathogen specific. While cell culture is still considered the "gold standard" for laboratory detection of respiratory viruses, slow response time and low sensitivity are suboptimal for routine detection practices.

In the study a new multiparameter test called RespiFinder was developed to detect 15 respiratory viruses in one reaction. Researchers then used the RespiFinder, as well as the cell culture method and a respiratory syncytial virus (RSV)-specific immunochromatography assay (ICA) to examine 144 clinical samples and compared the results. In most cases the RespiFinder was as effective or nearly as effective (more than 95%) as the cell culture, or "gold standard", in both sensitivity and specificity.

Only test results for rhinovirus and RSV came in under 95%. In addition, compared to the RSV-specific ICA, the RespiFinder showed a specificity and sensitivity of approximately 80%.

"The RespiFinder assay provides a user-friendly and high-throughput tool for the simultaneous detection of 15 respiratory viruses with excellent overall performance statistics," say the researchers.

Journal reference: M. Reijans, G. Dingemans, C.H. Klaassen, J.F. Meis, J. Keijdener, B. Mulders, K. Eadie, W. van Leeuwen, A. van Belkum, A.M. Horrevorts, G. Simons. 2008. RespiFinder: a new multiparameter test to differentially identify fifteen respiratory viruses. Journal of Clinical Microbiology, 46. 4: 1232-1240.


Story Source:

The above story is based on materials provided by American Society for Microbiology. Note: Materials may be edited for content and length.


Cite This Page:

American Society for Microbiology. "New Method Simultaneously Tests For Fifteen Respiratory Viruses." ScienceDaily. ScienceDaily, 27 April 2008. <www.sciencedaily.com/releases/2008/04/080425103124.htm>.
American Society for Microbiology. (2008, April 27). New Method Simultaneously Tests For Fifteen Respiratory Viruses. ScienceDaily. Retrieved April 23, 2014 from www.sciencedaily.com/releases/2008/04/080425103124.htm
American Society for Microbiology. "New Method Simultaneously Tests For Fifteen Respiratory Viruses." ScienceDaily. www.sciencedaily.com/releases/2008/04/080425103124.htm (accessed April 23, 2014).

Share This



More Health & Medicine News

Wednesday, April 23, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Big Pharma Braces for M&A Wave

Big Pharma Braces for M&A Wave

Reuters - Business Video Online (Apr. 22, 2014) Big pharma on the move as Novartis boss, Joe Jimenez, tells Reuters about plans to transform his company via an asset exchange with GSK, and Astra Zeneca shares surge on speculation that Pfizer is looking for a takeover. Joanna Partridge reports. Video provided by Reuters
Powered by NewsLook.com
Study Says Most Crime Not Linked To Mental Illness

Study Says Most Crime Not Linked To Mental Illness

Newsy (Apr. 22, 2014) A new study finds most crimes committed by people with mental illness are not caused by symptoms of their illness or disorder. Video provided by Newsy
Powered by NewsLook.com
Hagel Gets Preview of New High-Tech Projects

Hagel Gets Preview of New High-Tech Projects

AP (Apr. 22, 2014) Defense Secretary Chuck Hagel is given hands-on demonstrations Tuesday of some of the newest research from DARPA _ the military's Defense Advanced Research Projects Agency program. (April 22) Video provided by AP
Powered by NewsLook.com
How Smaller Plates And Cutlery Could Make You Feel Fuller

How Smaller Plates And Cutlery Could Make You Feel Fuller

Newsy (Apr. 22, 2014) NBC's "Today" conducted an experiment to see if changing the size of plates and utensils affects the amount individuals eat. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins