Featured Research

from universities, journals, and other organizations

Breast Cancer Tumors Grow Faster In Younger Women

Date:
May 8, 2008
Source:
BioMed Central/Breast Cancer Research
Summary:
A new approach to estimating tumor growth has been developed based on breast screening results from almost 400,000 women. This new model can also estimate the proportion of breast cancers which are detected at screening (screen test sensitivity). It provides a new approach to simultaneously estimating the growth rate of breast cancer and the ability of mammography screening to detect tumors.

A new approach to estimating tumour growth based on breast screening results from almost 400,000 women is published in Breast Cancer Research. This new model can also estimate the proportion of breast cancers which are detected at screening (screen test sensitivity). It provides a new approach to simultaneously estimating the growth rate of breast cancer and the ability of mammography screening to detect tumours.

Related Articles


The results of the study show that tumour growth rates vary considerably among patients, with generally slower growth rates with increasing age at diagnosis. Understanding how tumours grow is important in the planning and evaluation of screening programs, clinical trials, and epidemiological studies. However, studies of tumour growth rates in people have so far been based mainly on small and selected samples.

Now, Harald Weedon-Fekjær of the Department of Etiological Research, Cancer Registry of Norway and colleagues have developed a new estimating procedure to follow tumour growth in a very large population of breast cancer patients included in the Norwegian Breast Cancer Screening Program.

The researchers applied their model to cancer incidence and tumour measurement data from 395,188 women aged between 50 and 69 years old. They found that tumour growth varies considerably between subjects. About one in twenty tumours double in size in just over a month from 10 to 20mm, while similar numbers took more than six years to grow to this size. They estimated the mean time for a tumour to double in size from 10 to 20 mm in diameter is 1.7 years.

"There are enormous implications for the sensitivity of breast cancer screening programs" Weedon-Fekjær explains. "We found that mammography screen test sensitivity (STS) increases sharply with increased tumour size, as one might expect. Detection rates are just 26% for a 5 mm tumour but increase to 91% once a tumour is 10 mm in size." The team compared their model with the previously used Markov model for tumour progression, and found its predictive power to be almost twice as accurate as the Markov model, in addition to providing new estimates directly linked to tumour size.


Story Source:

The above story is based on materials provided by BioMed Central/Breast Cancer Research. Note: Materials may be edited for content and length.


Journal Reference:

  1. Breast cancer tumor growth estimated through mammography screening data. Harald HWF Weedon-Fekjaer, Bo Henry BHL Lindqvist, Odd Olai OOA Aalen, Lars Johan LJV Vatten and Steinar ST Tretli. Breast Cancer Research.

Cite This Page:

BioMed Central/Breast Cancer Research. "Breast Cancer Tumors Grow Faster In Younger Women." ScienceDaily. ScienceDaily, 8 May 2008. <www.sciencedaily.com/releases/2008/05/080508075221.htm>.
BioMed Central/Breast Cancer Research. (2008, May 8). Breast Cancer Tumors Grow Faster In Younger Women. ScienceDaily. Retrieved March 4, 2015 from www.sciencedaily.com/releases/2008/05/080508075221.htm
BioMed Central/Breast Cancer Research. "Breast Cancer Tumors Grow Faster In Younger Women." ScienceDaily. www.sciencedaily.com/releases/2008/05/080508075221.htm (accessed March 4, 2015).

Share This


More From ScienceDaily



More Health & Medicine News

Wednesday, March 4, 2015

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Adults Only Get The Flu Twice A Decade, Researchers Say

Adults Only Get The Flu Twice A Decade, Researchers Say

Newsy (Mar. 4, 2015) — Researchers found adults only get the flu about once every five years. Scientists analyzed how a person&apos;s immunity builds up over time as well. Video provided by Newsy
Powered by NewsLook.com
Mount Everest Has a Poop Problem

Mount Everest Has a Poop Problem

Buzz60 (Mar. 4, 2015) — With no bathrooms to use, climbers of Mount Everest have been leaving human waste on the mountain for years, and it&apos;s becoming a health issue. Mike Janela (@mikejanela) has more. Video provided by Buzz60
Powered by NewsLook.com
Obamacare's New Supreme Court Battle

Obamacare's New Supreme Court Battle

Washington Post (Mar. 4, 2015) — The Affordable Care Act is facing another challenge at the Supreme Court in King v. Burwell, which deals with subsidies for health insurance. The case could cut out a major provision of Obamacare, causing the law to unravel. Here’s what you need to know about the case. Video provided by Washington Post
Powered by NewsLook.com
Investigation Finds Hurt Workers Suffer More In Some States

Investigation Finds Hurt Workers Suffer More In Some States

Newsy (Mar. 4, 2015) — ProPublica and NPR&apos;s joint investigation found drastic cuts to workers compensation benefits and employees&apos; access to those benefits. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:

Strange & Offbeat Stories

 

Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins