Featured Research

from universities, journals, and other organizations

Weight Gain Within The Normal Range Increases Risk Of Chronic Kidney Disease

Date:
June 24, 2008
Source:
American Society of Nephrology
Summary:
Healthy individuals who gain weight, even to a weight still considered normal, are at risk for developing chronic kidney disease, according to a new study. The study suggests that CKD should be added to the list of conditions that are associated with weight gain, including diabetes and hypertension.

Healthy individuals who gain weight, even to a weight still considered normal, are at risk for developing chronic kidney disease (CKD), according to a study appearing in the Journal of the American Society Nephrology (JASN). The study suggests that CKD should be added to the list of conditions that are associated with weight gain, including diabetes and hypertension.

Related Articles


Research has shown that obesity is linked to an increased risk of CKD, but no studies have looked at the effects of weight gain within the "normal" range of an individual's body mass index. To investigate, Drs. Seungho Ryu and Yoosoo Chang of the Kangbuk Samsung Hospital in Seoul, Korea, and their colleagues conducted a prospective study of individuals who were of a healthy weight and had no known risk factors for chronic kidney disease.

In Korea, all workers participate in either annual or biennial health exams, as required by Korea's Industrial Safety and Health Law. As a result, the investigators had access to clinical data from thousands of individuals. For this study, they included 8,792 healthy men who participated in the health exams in 2002.

The researchers discovered a U-shaped association between weight change and development of CKD. Men who lost or gained a lot of weight (more than 0.75 kg per year) had the highest risk of developing CKD. Those whose weight changed minimally (within a range of -0.25 to <0.25 kg per year) had the lowest risk, even when factors such as body mass index, age, exercise, lipids, and blood glucose levels were taken into account.

The authors note that their finding of an increased risk associated with weight loss should be interpreted with caution. A number of factors may have complicated the results. For example, men with the most weight loss may have been less healthy at the start of the study.

According to Dr. Ryu, because the recommended weight for a person of a given height spans a wide range, individuals are not likely to be observant of weight fluctuations as long as they remain within the healthy range.

But this study shows that weight gain even within the normal range is significantly associated with an increased risk of developing CKD. "Our findings show that weight gain within 'the normal' weight range is clearly one of the risk factors in developing CKD, and initial low body mass index does not counteract the deleterious effect of weight gain. Therefore, avoidance of weight gain, even among lean individuals, is important to reduce the risk for this disease," the authors said.


Story Source:

The above story is based on materials provided by American Society of Nephrology. Note: Materials may be edited for content and length.


Journal Reference:

  1. Ryu et al. Changes in Body Weight Predict CKD in Healthy Men. Journal of the American Society of Nephrology, 2008 DOI: 10.1681/ASN.2007121286

Cite This Page:

American Society of Nephrology. "Weight Gain Within The Normal Range Increases Risk Of Chronic Kidney Disease." ScienceDaily. ScienceDaily, 24 June 2008. <www.sciencedaily.com/releases/2008/06/080619163115.htm>.
American Society of Nephrology. (2008, June 24). Weight Gain Within The Normal Range Increases Risk Of Chronic Kidney Disease. ScienceDaily. Retrieved October 25, 2014 from www.sciencedaily.com/releases/2008/06/080619163115.htm
American Society of Nephrology. "Weight Gain Within The Normal Range Increases Risk Of Chronic Kidney Disease." ScienceDaily. www.sciencedaily.com/releases/2008/06/080619163115.htm (accessed October 25, 2014).

Share This



More Health & Medicine News

Saturday, October 25, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

IKEA Desk Converts From Standing to Sitting With One Button

IKEA Desk Converts From Standing to Sitting With One Button

Buzz60 (Oct. 24, 2014) IKEA is out with a new convertible desk that can convert from a sitting desk to a standing one with just the push of a button. Jen Markham explains. Video provided by Buzz60
Powered by NewsLook.com
Ebola Protective Suits Being Made in China

Ebola Protective Suits Being Made in China

AFP (Oct. 24, 2014) A factory in China is busy making Ebola protective suits for healthcare workers and others fighting the spread of the virus. Duration: 00:38 Video provided by AFP
Powered by NewsLook.com
WHO: Millions of Ebola Vaccine Doses by 2015

WHO: Millions of Ebola Vaccine Doses by 2015

AP (Oct. 24, 2014) The World Health Organization said on Friday that millions of doses of two experimental Ebola vaccines could be ready for use in 2015 and five more experimental vaccines would start being tested in March. (Oct. 24) Video provided by AP
Powered by NewsLook.com
Doctor in NYC Quarantined With Ebola

Doctor in NYC Quarantined With Ebola

AP (Oct. 24, 2014) An emergency room doctor who recently returned to the city after treating Ebola patients in West Africa has tested positive for the virus. He's quarantined in a hospital. (Oct. 24) Video provided by AP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins