Featured Research

from universities, journals, and other organizations

Bosentan Improves Quality Of Life For Patients With Pulmonary Hypertension

Date:
July 24, 2008
Source:
Wiley - Blackwell
Summary:
Recent studies have shown that bosentan therapy greatly improves the quality of life for patients with pulmonary arterial hypertension. According to a new study treatments with oral Bosentan reduces resistance in blood flow -- allowing the heart and lungs to work more efficiently and in turn, enables patients to increase exercise capacity and quality of life.

Recent studies have shown that bosentan therapy greatly improves the quality of life for patients with pulmonary arterial hypertension (PAH). According to a study in Respirology published by Wiley-Blackwell, treatments with oral Bosentan reduces resistance in blood flow – allowing the heart and lungs to work more efficiently and in turn, enables patients to increase exercise capacity and quality of life.

PAH is a syndrome where one experiences continuous high blood pressure in the pulmonary arteries, or the blood vessels supplying blood to the lungs. In PAH, the heart has to work very hard to pump against the high resistance and eventually weakens. When it loses the ability to pump enough blood, heart failure occurs and often death.

Although there is no cure for PAH, there are treatments that are beneficial to the patients. Bosentan is an oral endothelin receptor antagonist that significantly improves functional status, increase blood flow and survival of patients.

Lead author, Mr. Geoff Strange says, “Quality of life is an important consideration in the treatment of diseases such as PAH, in which prognosis is typically poor. In such chronic diseases, patients view improvement in quality of life as an important measure of treatment success.”

After three months of Bosentan treatment, patients showed improvements in their exercise capacity in the six minute walk test (6MWT), as well as domains that measured quality of life. Although the assessment of quality of life and 6MWT provides complementary data at individual time points, they did not correlate over time as a response to therapy.

Professor Eli Gabbay, from the Royal Perth Hospital and The University of Western Australia adds, “While quality of life and 6MWT data were parallel at individual points, quality of life may improve on Bosentan therapy independent of the improvements in 6MWT. The quality of life domains should be specifically assessed to improve the monitoring of patients with PAH as changes in quality of life cannot be extrapolated from routine clinical variables.”


Story Source:

The above story is based on materials provided by Wiley - Blackwell. Note: Materials may be edited for content and length.


Cite This Page:

Wiley - Blackwell. "Bosentan Improves Quality Of Life For Patients With Pulmonary Hypertension." ScienceDaily. ScienceDaily, 24 July 2008. <www.sciencedaily.com/releases/2008/07/080723170836.htm>.
Wiley - Blackwell. (2008, July 24). Bosentan Improves Quality Of Life For Patients With Pulmonary Hypertension. ScienceDaily. Retrieved July 31, 2014 from www.sciencedaily.com/releases/2008/07/080723170836.htm
Wiley - Blackwell. "Bosentan Improves Quality Of Life For Patients With Pulmonary Hypertension." ScienceDaily. www.sciencedaily.com/releases/2008/07/080723170836.htm (accessed July 31, 2014).

Share This




More Health & Medicine News

Thursday, July 31, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

House Republicans Vote to Sue Obama Over Healthcare Law

House Republicans Vote to Sue Obama Over Healthcare Law

Reuters - US Online Video (July 31, 2014) The Republican-led House of Representatives votes to sue President Obama, accusing him of overstepping his executive authority in making changes to the Affordable Care Act. Mana Rabiee reports. Video provided by Reuters
Powered by NewsLook.com
Despite Health Questions, E-Cigs Are Beneficial: Study

Despite Health Questions, E-Cigs Are Beneficial: Study

Newsy (July 31, 2014) Citing 81 previous studies, new research out of London suggests the benefits of smoking e-cigarettes instead of regular ones outweighs the risks. Video provided by Newsy
Powered by NewsLook.com
Dangerous Bacteria Kills One in Florida

Dangerous Bacteria Kills One in Florida

AP (July 31, 2014) Sarasota County, Florida health officials have issued a warning against eating raw oysters and exposing open wounds to coastal and inland waters after a dangerous bacteria killed one person and made another sick. (July 31) Video provided by AP
Powered by NewsLook.com
Health Insurers' Profits Slide

Health Insurers' Profits Slide

Reuters - Business Video Online (July 30, 2014) Obamacare-related costs were said to be behind the profit plunge at Wellpoint and Humana, but Wellpoint sees the new exchanges boosting its earnings for the full year. Fred Katayama reports. Video provided by Reuters
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



    Save/Print:
    Share:

    Free Subscriptions


    Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

    Get Social & Mobile


    Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

    Have Feedback?


    Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
    Mobile: iPhone Android Web
    Follow: Facebook Twitter Google+
    Subscribe: RSS Feeds Email Newsletters
    Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins