Featured Research

from universities, journals, and other organizations

Adding Taxotere To Chemotherapy Regimen Improves Survival In Early Breast Cancer, Study Suggests

Date:
September 16, 2008
Source:
European Society for Medical Oncology (ESMO)
Summary:
For patients with early stage breast cancer that has spread to the lymph nodes, adding four cycles of docetaxel (Taxotere) into a sequential regimen of epirubicin followed by cyclophosphamide, methotrexate and fluorouracil (CMF) reduces the risk of recurrence and death, updated long-term results show.

For patients with early stage breast cancer that has spread to the lymph nodes, adding four cycles of docetaxel (Taxotere) into a sequential regimen of epirubicin followed by cyclophosphamide, methotrexate and fluorouracil (CMF) reduces the risk of recurrence and death, updated long-term results show.

Related Articles


This advantage comes at the cost of an increased, but manageable, toxicity, Italian researchers report at the 33rd Congress of the European Society for Medical Oncology (ESMO) in Stockholm.

Dr. Francesco Cognetti from Istituto Oncologico Regina Elena and colleagues treated 998 patients with node-positive early stage breast cancer with one of two regimens: 486 received four months of treatment with epirubicin, followed by four cycles of treatment with CMF. The remainder received an additional docetaxel treatment between the two chemotherapy stages.

At the congress, Dr. Cognetti reports results from a median follow-up of 62 months, showing a disease-free survival rate of 74% in the docetaxel arm, compared to 68% among women treated with the other regimen.

“At a median follow-up of five years, the overall survival of patients receiving the addition of docetaxel to the standard regimen of epirubicin followed by CMF significantly improved compared to patients randomized in the control arm,” he said. “Moreover, the time of disease recurrence results significantly longer in patients enrolled in the experimental arm.”

“The trial demonstrates that the introduction of four cycles of docetaxel into a sequential epirubicin-CMF regimen reduces the risk of recurrence and death in node-positive breast cancer patients.”


Story Source:

The above story is based on materials provided by European Society for Medical Oncology (ESMO). Note: Materials may be edited for content and length.


Cite This Page:

European Society for Medical Oncology (ESMO). "Adding Taxotere To Chemotherapy Regimen Improves Survival In Early Breast Cancer, Study Suggests." ScienceDaily. ScienceDaily, 16 September 2008. <www.sciencedaily.com/releases/2008/09/080915083801.htm>.
European Society for Medical Oncology (ESMO). (2008, September 16). Adding Taxotere To Chemotherapy Regimen Improves Survival In Early Breast Cancer, Study Suggests. ScienceDaily. Retrieved December 20, 2014 from www.sciencedaily.com/releases/2008/09/080915083801.htm
European Society for Medical Oncology (ESMO). "Adding Taxotere To Chemotherapy Regimen Improves Survival In Early Breast Cancer, Study Suggests." ScienceDaily. www.sciencedaily.com/releases/2008/09/080915083801.htm (accessed December 20, 2014).

Share This


More From ScienceDaily



More Health & Medicine News

Saturday, December 20, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

The Best Tips to Curb Holiday Carbs

The Best Tips to Curb Holiday Carbs

Buzz60 (Dec. 19, 2014) It's hard to resist those delicious but fattening carbs we all crave during the winter months, but there are some ways to stay satisfied without consuming the extra calories. Vanessa Freeman (@VanessaFreeTV) has the details. Video provided by Buzz60
Powered by NewsLook.com
Sierra Leone Bikers Spread the Message to Fight Ebola

Sierra Leone Bikers Spread the Message to Fight Ebola

AFP (Dec. 19, 2014) More than 100 motorcyclists hit the road to spread awareness messages about Ebola. Nearly 7,000 people have now died from the virus, almost all of them in west Africa, according to the World Health Organization. Video provided by AFP
Powered by NewsLook.com
Researchers Test Colombian Village With High Alzheimer's Rates

Researchers Test Colombian Village With High Alzheimer's Rates

AFP (Dec. 19, 2014) In Yarumal, a village in N. Colombia, Alzheimer's has ravaged a disproportionately large number of families. A genetic "curse" that may pave the way for research on how to treat the disease that claims a new victim every four seconds. Duration: 02:42 Video provided by AFP
Powered by NewsLook.com
The Best Protein-Filled Foods to Energize You for the New Year

The Best Protein-Filled Foods to Energize You for the New Year

Buzz60 (Dec. 19, 2014) The new year is coming and nothing will energize you more for 2015 than protein-filled foods. Fitness and nutrition expert John Basedow (@JohnBasedow) gives his favorite high protein foods that will help you build muscle, lose fat and have endless energy. Video provided by Buzz60
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins